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(Circulation. 2006;114:e485-e486.)
© 2006 American Heart Association, Inc.

Images in Cardiovascular Medicine

An Unusual Explanation for Episodic Dyspnea

Gregory Piazza, MD; Joseph P. Carrozza, Jr, MD; Peter J. Zimetbaum, MD

From the Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass.

Correspondence to Gregory Piazza, MD, Cardiovascular Division, Beth Israel Deaconess Medical Center, One Deaconess Rd, Baker 4, Boston, MA 02215. E-mail gpiazza@bidmc.harvard.edu

An extract of the first 250 words of the full text is provided, because this article has no abstract.

An 88-year-old woman with a nonischemic cardiomyopathy, severe kyphoscoliosis, and an implantable cardiac defibrillator presented from her nursing home with dyspnea and hypoxemia. She had several recent hospitalizations for similar symptoms that were attributed to heart failure and pneumonia. On the day of presentation, she had severe dyspnea while eating breakfast. In the emergency department, her physical examination was remarkable for an oxygen saturation of 94% on 100% nonrebreather mask, which was minimally changed from baseline pulse oximetry on room air. Laboratory evaluation was notable for hypoxemia, with a pO₂ of 61 mm Hg. ECG and chest radiography were unremarkable. Chest computed tomography with contrast revealed a dilated thoracic aorta without dissection and no evidence of pulmonary embolism. A transthoracic echocardiogram demonstrated moderate global left ventricular hypokinesis, preserved right ventricular systolic function, normal estimated pulmonary artery pressures, mild aortic regurgitation, and an aneurysmal interatrial septum with right-to-left shunt on color Doppler. The patient continued to have episodic dyspnea with desaturation, and a cardiologist was consulted. During the consultation, her oxygen saturation decreased to 67% in the upright position, with or without supplemental oxygen, and increased to 94% in the recumbent position. A bedside transthoracic echocardiogram revealed a resting right-to-left shunt in the recumbent position that increased in the upright position (Figure 1). These findings were consistent with platypnea-orthodeoxia. Transesophageal echocardiography revealed a patent foramen ovale. She subsequently underwent cardiac catheterization with successful transcatheter closure of the patent foramen ovale (Figure 2). After closure, her oxygen . . . [Full Text of this Article]

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Circulation 2006 114: 1133. [Extract] [Full Text]