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(Circulation. 2006;113:2943-2946.)
© 2006 American Heart Association, Inc.

ADA/AHA Scientific Statement

Preventing Cardiovascular Disease and Diabetes

A Call to Action From the American Diabetes Association and the American Heart Association

Robert H. Eckel, MD; Richard Kahn, PhD; Rose Marie Robertson, MD; Robert A. Rizza, MD

An extract of the first 250 words of the full text is provided, because this article has no abstract.

	Introduction

 
Excess body weight has become a major public health problem in the U.S., with nearly two-thirds of adults either overweight or obese.¹ The steady gain in the prevalence of obesity over the last 25 years has affected our entire population—no racial or ethnic group, no region of the country, and no socioeconomic group has been spared.² Perhaps most worrisome is the observation that the rise in the rate of obesity has been greatest in children and minorities, which suggests that future generations of Americans, and our fastest growing populations, may bear the ultimate burden of this condition.³

Overweight or obesity results in a wide range of elevated risk factors and many fatal and nonfatal conditions.⁴ Paradoxically, although we have witnessed decades in which heart disease and stroke have steadily declined and cancer mortality has at worse remained stable,⁵ the prevalence of diabetes has soared.⁶ The increase in diabetes can largely be attributed to weight gain,^7,8 and it threatens the enormous advances in disease prevention we have seen.^3,9,10

Among individuals with diabetes, cardiovascular disease (CVD) is the leading cause of morbidity and mortality^9,11; adults with diabetes have a two- to fourfold higher risk of CVD compared with those without diabetes.^12,13 Diabetes is also accompanied by a significantly increased prevalence of hypertension and dyslipidemia.¹⁴

It is reasonable to postulate that in many individuals, excess weight gives rise to diabetes, hypertension, and dyslipidemia, thereby leading to frank CVD.^15–17 This seemingly simple algorithm is undoubtedly more complex because (1) many studies show that . . . [Full Text of this Article]

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