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(Circulation. 2005;111:127-135.)
© 2005 American Heart Association, Inc.
Arrhythmia/Electrophysiology |
From the II. Medizinische Abteilung, Allgemeines Krankenhaus St Georg, Hamburg, Germany.
Correspondence to Dr Feifan Ouyang, II. Medizinische Abteilung, Allgemeines Krankenhaus St Georg, Lohmühlenstraße 5, 20099 Hamburg, Germany. E-mail ouyangfeifan{at}aol.com
Received June 8, 2004; revision received October 10, 2004; accepted October 13, 2004.
Background Atrial tachyarrhythmias (ATa) can recur after continuous circular lesions (CCLs) around the ipsilateral pulmonary veins (PVs) in patients with atrial fibrillation (AF). This study characterizes the electrophysiological findings in patients with and without ATa after complete PV isolation.
Methods and Results Twenty-nine of 100 patients had recurrent ATa after complete PV isolation by use of CCLs during a mean follow-up of
8 months. A repeat procedure was performed in 26 patients with ATa and in 7 volunteers without ATa at 3 to 4 months after CCLs. No recovered PV conduction was demonstrated in the 7 volunteers, whereas recovered PV conduction was found in 21 patients with recurrent ATa (right-sided PVs in 9 patients and left-sided PVs in 16 patients). The interval from the onset of the P wave to the earliest PV spike was 157±66 ms in the right-sided PVs and 149±45 ms in the left-sided PVs. During the procedure, PV tachycardia activated the atrium and resulted in atrial tachycardia (AT) in 10 patients. All conduction gaps were successfully closed with segmental RF ablation. After PV isolation, macroreentrant AT was induced and ablated in 3 patients. In the 5 patients without PV conduction, focal AT in the left atrial roof in 2 patients and non-PV foci in the left atrium in 1 patient were successfully abolished; in the remaining 2 patients, no ablation was performed because of noninducible arrhythmias. During a mean follow-up of
6 months, 24 patients were free of ATa without antiarrhythmic drugs.
Conclusions In patients with recurrent ATa after CCLs, recovered PV conduction is a dominant finding in
80% of patients and can be successfully eliminated by segmental RF ablation. Also, mapping and ablation of non-PV arrhythmias can improve clinical success.
Key Words: atrium arrhythmia ablation mapping tachyarrhythmias
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