Published online before print July 1, 2002, doi: 10.1161/01.CIR.0000023621.88708.62
| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
(Circulation. 2002;106:511.)
© 2002 American Heart Association, Inc.
Basic Science Reports |
Magnetic Resonance–Guided Placement of Atrial Septal Closure Device in Animal Model of Patent Foramen Ovale
From the Clinic of Diagnostic Radiology (A.B., E.S., F.F., R.W.G.) and the Clinic of Pediatric Cardiology (E.G.M.), University of Technology Aachen, Aachen, Germany; the Department of Pediatric Cardiology (R.G.), Kiel University, Kiel, Germany; Philips Research Laboratories (T.S.), Hamburg, Germany; and Philips Medical Systems (J.J.v.V.), Best, the Netherlands.
Correspondence to Arno Buecker, MD, Clinic of Diagnostic Radiology, Pauwelsstr. 30, D-52057 Aachen, Germany. E-mail buecker{at}rad.rwth-aachen.de
Background— Percutaneous closure of the patent foramen ovale (PFO) is usually performed under x-ray in combination with ultrasound guidance. We tested the feasibility of applying magnetic resonance (MR) guidance for percutaneous closure of PFO in an animal model, thus avoiding the disadvantage of ionizing radiation.
Methods and Results— Real-time MRI with radial or spiral k-space filling (15 frames per second) on an interventional 1.5-T high-field whole-body system was exploited to examine the feasibility of MR-guided closure of the PFO in 7 piglets weighing 
14 kg. A specially designed prototype nonmagnetic closure device was introduced via the femoral vein. The short bore of the magnet and in-room monitors allowed for visualization and steering of the catheter with the loaded occluder. Catheterization of the left atrium and, finally, correct placement of the device was possible in all animals. Deployment of the device was depicted by real-time MR, and initial misplacement, which occurred in 2 animals, was easily detected and corrected.
Conclusions— Real-time MR guidance of PFO closure, without the use of ionizing radiation, is feasible in an animal model.
Key Words: magnetic resonance imaging • catheterization • defects
This article has been cited by other articles:
 |
|
 |
|
  S. Nazarian, A. Kolandaivelu, M. M. Zviman, G. R. Meininger, R. Kato, R. C. Susil, A. Roguin, T. L. Dickfeld, H. Ashikaga, H. Calkins, et al. Feasibility of Real-Time Magnetic Resonance Imaging for Catheter Guidance in Electrophysiology Studies Circulation, July 15, 2008; 118(3): 223 - 229. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. S. Baim and R. Y. Kwong Is Magnetic Resonance Image Guidance the Key to Opening Chronic Total Occlusions? Circulation, February 28, 2006; 113(8): 1053 - 1055. [Full Text] [PDF]
|
|
|
|
|
|
A. N. Raval, P. V. Karmarkar, M. A. Guttman, C. Ozturk, S. Sampath, R. DeSilva, R. J. Aviles, M. Xu, V. J. Wright, W. H. Schenke, et al. Real-Time Magnetic Resonance Imaging-Guided Endovascular Recanalization of Chronic Total Arterial Occlusion in a Swine Model Circulation, February 28, 2006; 113(8): 1101 - 1107. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. J. Lederman Cardiovascular Interventional Magnetic Resonance Imaging Circulation, November 8, 2005; 112(19): 3009 - 3017. [Full Text] [PDF]
|
|
|
|
|
|
A. N. Raval, J. D. Telep, M. A. Guttman, C. Ozturk, M. Jones, R. B. Thompson, V. J. Wright, W. H. Schenke, R. DeSilva, R. J. Aviles, et al. Real-Time Magnetic Resonance Imaging-Guided Stenting of Aortic Coarctation With Commercially Available Catheter Devices in Swine Circulation, August 2, 2005; 112(5): 699 - 706. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 V. K. Raman, P. V. Karmarkar, M. A. Guttman, A. J. Dick, D. C. Peters, C. Ozturk, B. S.S. Pessanha, R. B. Thompson, A. N. Raval, R. DeSilva, et al. Real-Time Magnetic Resonance-Guided Endovascular Repair of Experimental Abdominal Aortic Aneurysm in Swine J. Am. Coll. Cardiol., June 21, 2005; 45(12): 2069 - 2077. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. A. Krombach, J. G. Pfeffer, S. Kinzel, M. Katoh, R. W. Gunther, and A. Buecker MR-guided Percutaneous Intramyocardial Injection with an MR-compatible Catheter: Feasibility and Changes in T1 Values after Injection of Extracellular Contrast Medium in Pigs Radiology, May 1, 2005; 235(2): 487 - 494. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R Corti, J Badimon, G Mizsei, F Macaluso, M Lee, P Licato, J F Viles-Gonzalez, V Fuster, and W Sherman Real time magnetic resonance guided endomyocardial local delivery Heart, March 1, 2005; 91(3): 348 - 353. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I M Barbash, J Leor, M S Feinberg, A Tessone, S Aboulafia-Etzion, A Orenstein, J Ruiz-Cabello, J S Cohen, and Y Mardor Interventional magnetic resonance imaging for guiding gene and cell transfer in the heart Heart, January 1, 2004; 90(1): 87 - 91. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. J. Dick, M. A. Guttman, V. K. Raman, D. C. Peters, B. S.S. Pessanha, J. M. Hill, S. Smith, G. Scott, E. R. McVeigh, and R. J. Lederman Magnetic Resonance Fluoroscopy Allows Targeted Delivery of Mesenchymal Stem Cells to Infarct Borders in Swine Circulation, December 9, 2003; 108(23): 2899 - 2904. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Schalla, M. Saeed, C. B. Higgins, A. Martin, O. Weber, and P. Moore Magnetic Resonance-Guided Cardiac Catheterization in a Swine Model of Atrial Septal Defect Circulation, October 14, 2003; 108(15): 1865 - 1870. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Haage, W. Piroth, G. Krombach, S. Karaagac, T. Schaffter, R. W. Gunther, and A. Bucker Pulmonary Embolism: Comparison of Angiography with Spiral Computed Tomography, Magnetic Resonance Angiography, and Real-Time Magnetic Resonance Imaging Am. J. Respir. Crit. Care Med., March 1, 2003; 167(5): 729 - 734. [Abstract] [Full Text] [PDF]
|
|