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(Circulation. 2000;102:2204.)
© 2000 American Heart Association, Inc.

Clinical Investigation and Reports

Change in Level of Physical Activity and Risk of All-Cause Mortality or Reinfarction

The Corpus Christi Heart Project

Lyn Steffen-Batey, PhD, MPH; Milton Z. Nichaman, MD, ScD; David C. Goff, Jr, MD, PhD; Ralph F. Frankowski, PhD; Craig L. Hanis, PhD; David J. Ramsey, PhD; Darwin R. Labarthe, MD, PhD

From the University of Texas-Houston Health Science Center, School of Public Health.

Correspondence to Lyn Steffen-Batey, PhD, MPH, University of Minnesota School of Public Health, Division of Epidemiology, 1300 South Second Street, Suite 300, Minneapolis, MN 55454. E-mail steffen{at}epi.umn.edu

Background—The role of physical activity (PA) in reducing the risk of all-cause mortality or reinfarction after a first myocardial infarction (MI) remains unresolved, particularly for minority populations. The association between change in level of PA and risk of death or reinfarction was studied in 406 Mexican American and non-Hispanic white women and men who survived a first MI.

Methods and Results—MI patients were interviewed at baseline and annually thereafter about PA, medical history, and risk factors of coronary heart disease. Change in level of PA after the index MI was categorized as (1) sedentary, no change (referent group), (2) decreased activity, (3) increased activity, and (4) active, no change. Over a 7-year period, the relative risk (95% CI) of death was as follows: 0.21 (0.10 to 0.44) for the active, no change group; 0.11 (0.03 to 0.46) for the increased activity group; and 0.49 (0.26 to 0.90) for the decreased activity group. The relative risk of reinfarction was as follows: 0.40 (0.24 to 0.66) for the active, no change group; 0.22 (0.09 to 0.50) for the increased activity group; and 0.93 (0.59 to 1.42) for the decreased activity group.

Conclusions—These findings are consistent with a beneficial role of PA for Mexican American and non-Hispanic white women and men who survive a first MI and have practical implications for the management of MI survivors.

Key Words: myocardial infarction • epidemiology • prevention

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