Circulation. 2000;101:e221-e222
(Circulation. 2000;101:e221.)
© 2000 American Heart Association, Inc.
Circulation Electronic Pages |
Noninvasive Detection of Coronary Artery Stenosis by Multislice Helical Computed Tomography
Andreas Knez, MD;
Christoph Becker, MD;
Bernd Ohnesorge, PhD;
Ralph Haberl, MD;
Maximilian Reiser, MD;
Gerhard Steinbeck, MD
From Medical Hospital I (A.K., R.H., G.S.) and Institute for Diagnostic
Radiology (C.B., M.R.), University of Munich, and Siemens Medical Engineering,
Forchheim (B.O.), Germany.
Correspondence to Andreas Knez, MD, Medical Hospital I, Ludwig-Maximilians-University München, Klinikum Grosshadern, Marchioninistraße 15, München, D-81377 Germany. E-mail knez{at}med1.med.uni-muenchen.de
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Introduction
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Top
Introduction
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Noninvasive
detection of coronary artery stenosis with noninvasive
imaging
modalities (electron beam CT, MR angiography) has recently
emerged.
The use of helical CT in the visualization of epicardial
coronary
arteries is limited by cardiac motion artifacts due to
long
acquisition times and lack of an ECG trigger and is therefore
reliable
only in the determination of coronary graft patency.
With the
introduction of a novel CT technology using a 4-slice CT
system
with shorter acquisition times and retrospectively ECG-gated
helical
scanning (Somatom Plus4VZ, Siemens), these limitations have
been
overcome. The helical CT system uses a multislice technique
(simultaneous
acquisition of 4 axial slices) with 250-ms
temporal resolution
and retrospective ECG gating. The scan starts 25
seconds after
the injection of 140 mL of nonionic contrast medium
(Ultravist
300, Schering) via a peripheral vein during 1
breathhold (acquisition
time, 28±4 seconds) with
simultaneous registration of
the ECG signal. Images of the
entire heart and the coronary
vessels are nearly motion-free.
After the acquisition, all images
are transferred to an external
workstation, and the ECG signal
is used to reconstruct the images at
identical time points,
500 ms before the next R wave (retrospective ECG
gating). For
3D reconstruction and visualization of the
coronary arteries,
volume rendering techniques are applied
(Insight; NeoImagery).
Figure 1
represents the results
of multislice CT angiography of a 77-year-old woman referred to our
hospital for evaluation of atypical chest pain. Exercise testing could
not be performed because of peripheral artery disease. In
addition to some calcified plaque, a high-grade stenosis of the
proximal part of the left anterior descending coronary artery
(LAD) was detected. In Figure 2
, an occlusion of the middle part of the right coronary artery
(RCA) is evident. The results of noninvasive coronary
angiography were confirmed by conventional
angiography.

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Figure 1. 3D rendering of left coronary artery
shows, in addition to some calcified plaques (arrowheads), high-grade
stenosis (arrow) in proximal part of LAD that could be
confirmed with conventional angiography. Ao. indicates ascending aorta;
T.p., pulmonary trunk.
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Figure 2. 3D rendering of occlusion (arrow) within
middle segment of RCA and extensive calcification (arrowheads).
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Footnotes
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The editor of Images in Cardiovascular Medicine is Hugh A. McAllister,
Jr, MD, Chief, Department of Pathology, St Lukes Episcopal
Hospital and Texas Heart Institute, and Clinical Professor of
Pathology, University of Texas Medical School and Baylor College
of Medicine.
Circulation encourages readers to submit cardiovascular images to the Circulation Editorial Office, St Lukes Episcopal Hospital/Texas Heart Institute, 6720 Bertner Ave, MC1-267, Houston, TX 77030.
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