(Circulation. 1999;100:465-467.)
© 1999 American Heart Association, Inc.
Brief Rapid Communications |
From the Division of Cardiology, Loyola University Medical Center, Maywood, Ill.
Correspondence to Eric K. Louie, MD, Professor of Medicine, Associate Director, Division of Cardiology, Loyola University Medical Center, Maywood, IL 60153.
BackgroundAnalysis of right ventricular adaptation to tricuspid regurgitation was studied in 10 heart transplant recipients following inadvertent endomyocardial biopsy disruption of the tricuspid apparatus.
Methods and ResultsEchocardiography demonstrated progressive diastolic right ventricular cavity enlargement (19.5±5.0 to 30.3±5.4 cm2, P<0.0002), with disproportionate elongation along the midminor axis (3.5±0.6 to 5.0±0.5 cm, P<0.001). As the right ventricle remodeled to more spherical (and less elliptical) proportions, the end-diastolic right ventricular midminor axis/long axis ratio increased significantly from 0.52±0.10 to 0.68±0.07, P<0.005.
ConclusionsVentricular enlargement due to right ventricular volume overload results in disproportionate dilation along the free wall to septum minor axis.
Key Words: ventricles regurgitation right ventricular volume overload tricuspid regurgitation orthotopic heart transplantation
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