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on February 21, 2005

Circulation. 2005
Published online before print February 21, 2005, doi: 10.1161/01.CIR.0000156462.97532.8F
A more recent version of this article appeared on March 1, 2005
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Submitted on May 20, 2004
Revised on October 6, 2004
Accepted on November 10, 2004

Artifact-Free Coronary Magnetic Resonance Angiography and Coronary Vessel Wall Imaging in the Presence of a New, Metallic, Coronary Magnetic Resonance Imaging Stent

Elmar Spuentrup MD, Alexander Ruebben MD, Andreas Mahnken MD, Matthias Stuber PhD, Christian Kölker MS, Trung Hieu Nguyen BS, Rolf W. Günther MD, and Arno Buecker MD*

From the Department of Diagnostic Radiology (E.S., A.R., A.M., C.K., T.H.N., R.W.G., A.B.), Technical University of Aachen, Aachen, Germany, and Johns Hopkins University School of Medicine (M.S.), Baltimore, Md.

* To whom correspondence should be addressed. E-mail: buecker{at}rad.rwth-aachen.de.

Background--Coronary in-stent restenosis cannot be directly assessed by magnetic resonance angiography (MRA) because of the local signal void of currently used stainless steel stents. The aim of this study was to investigate the potential of a new, dedicated, coronary MR imaging (MRI) stent for artifact-free, coronary MRA and in-stent lumen and vessel wall visualization.

Methods and Results--Fifteen prototype stents were deployed in coronary arteries of 15 healthy swine and investigated with a double-oblique, navigator-gated, free-breathing, T2-prepared, 3D cartesian gradient-echo sequence; a T2-prepared, 3D spiral gradient-echo sequence; and a T2-prepared, 3D steady-state, free-precession coronary MRA sequence. Furthermore, black-blood vessel wall imaging by a dual-inversion-recovery, turbo spin-echo sequence was performed. Artifacts of the stented vessel segment and signal intensities of the coronary vessel lumen inside and outside the stent were assessed. With all investigated sequences, the vessel lumen and wall could be visualized without artifacts, including the stented vessel segment. No signal intensity alterations inside the stent when compared with the vessel lumen outside the stent were found.

Conclusions--The new, coronary MRI stent allows for completely artifact-free coronary MRA and vessel wall imaging.


Key words: stents • artifacts • restenosis • magnetic resonance imaging • coronary disease




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