on May 5, 2003
Circulation. 2003
Published online before print May 5, 2003, doi: 10.1161/01.CIR.0000070931.62772.4E
Published online before print May 5, 2003, doi: 10.1161/01.CIR.0000070931.62772.4E
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Submitted on January 29, 2003
From Johns Hopkins University, School of Medicine, Departments of Radiology (D.L.K., E.A., J.W.M.B.) and Medicine, Division of Cardiology (A.W.H., L.C.A., J.M.H.), Baltimore, Md; Osiris Therapeutics, Inc (B.J.M., M.F.P.), Baltimore, Md; and Department of Electrical and Electronics Engineering, Bilkent University, Ankara, Turkey (E.A.). * To whom correspondence should be addressed. E-mail: dara{at}mri.jhu.edu.
Background--We investigated the potential of magnetic resonance imaging (MRI) to track magnetically labeled mesenchymal stem cells (MR-MSCs) in a swine myocardial infarction (MI) model. Methods and Results--Adult farm pigs (n=5) were subjected to closed-chest experimental MI. MR-MSCs (2.8 to 16x107 cells) were injected intramyocardially under x-ray fluoroscopy. MRIs were obtained on a 1.5T MR scanner to demonstrate the location of the MR-MSCs and were correlated with histology. Contrast-enhanced MRI demonstrated successful injection in the infarct and serial MSC tracking was demonstrated in two animals. Conclusion--MRI tracking of MSCs is feasible and represents a preferred method for studying the engraftment of MSCs in MI.
Revised on March 25, 2003
Accepted on March 26, 2003
In Vivo Magnetic Resonance Imaging of Mesenchymal Stem Cells in Myocardial Infarction
Dara L. Kraitchman VMD, PhD*,
Key words: magnetic resonance imaging • myocardial infarction • cells • contrast media
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|
|
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|
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|
|
|
 |
|
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|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
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|
|
|
|
 |
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
 I. Dimarakis, N. A. Habib, and M. Y.A. Gordon Adult bone marrow-derived stem cells and the injured heart: just the beginning? Eur. J. Cardiothorac. Surg., November 1, 2005; 28(5): 665 - 676. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
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|
|
|
|
|
|
R. R. Edelman Contrast-enhanced MR Imaging of the Heart: Overview of the Literature Radiology, September 1, 2004; 232(3): 653 - 668. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
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|
|
|
|
 |
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
 M. S. Lee and R. R. Makkar Stem-Cell Transplantation in Myocardial Infarction: A Status Report Ann Intern Med, May 4, 2004; 140(9): 729 - 737. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
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|
|
|
|
 |
|
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|
|
|
|
|
|
P D Lambiase and M S Marber Myocardial gene and cell delivery Heart, January 1, 2004; 90(1): 1 - 2. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
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|
|