on April 22, 2002
Circulation. 2002
Published online before print April 22, 2002, doi: 10.1161/01.CIR.0000016043.87291.33
Published online before print April 22, 2002, doi: 10.1161/01.CIR.0000016043.87291.33
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Submitted on August 14, 2001
From the Division of Cardiovascular Diseases and Internal Medicine (C.S.R., P.B.B., H.H.T., P.J.B., M.S., M.R.B., G.W.B., V.M., K.N.G., D.R.H.), Division of Hypertension and Internal Medicine (S.C.T.), and the Section of Biostatistics (D.E.G.), Mayo Clinic, Rochester, Minn.
Background—In patients undergoing percutaneous coronary intervention (PCI) in the modern era, the incidence and prognostic implications of acute renal failure (ARF) are unknown. Methods and Results—With a retrospective analysis of the Mayo Clinic PCI registry, we determined the incidence of, risk factors for, and prognostic implications of ARF (defined as an increase in serum creatinine [Cr] >0.5 mg/dL from baseline) after PCI. Of 7586 patients, 254 (3.3%) experienced ARF. Among patients with baseline Cr <2.0, the risk of ARF was higher among diabetic than nondiabetic patients, whereas among those with a baseline Cr >2.0, all had a significant risk of ARF. In multivariate analysis, ARF was associated with baseline serum Cr, acute myocardial infarction, shock, and volume of contrast medium administered. Twenty-two percent of patients with ARF died during the index hospitalization compared with only 1.4% of patients without ARF (P<0.0001). After adjustment, ARF remained strongly associated with death. Among hospital survivors with ARF, 1- and 5-year estimated mortality rates were 12.1% and 44.6%, respectively, much greater than the 3.7% and 14.5% mortality rates in patients without ARF (P<0.0001). Conclusions—The overall incidence of ARF after PCI is low. Diabetic patients with baseline Cr values <2.0 mg/dL are at higher risk than nondiabetic patients, whereas all patients with a serum Cr >2.0 are at high risk for ARF. ARF was highly correlated with death during the index hospitalization and after dismissal.
Revised on March 6, 2002
Accepted on March 6, 2002
Incidence and Prognostic Importance of Acute Renal
Failure After Percutaneous Coronary
Intervention
Charanjit S. Rihal MD*,
Key words: coronary disease • kidney • acute renal failure • angioplasty • stents
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|
|
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|
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|
|
|
|
|
|
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|
|
|
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|
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|
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|
|
|
|
 |
|
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|
|
|
|
|
|
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|
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|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
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|
|
|
|
 |
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
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|
|
|
|
|
|
M. Moscucci, E. K. Rogers, C. Montoye, D. E. Smith, D. Share, M. O'Donnell, A. Maxwell-Eward, W. L. Meengs, A. C. De Franco, K. Patel, et al. Association of a Continuous Quality Improvement Initiative With Practice and Outcome Variations of Contemporary Percutaneous Coronary Interventions Circulation, February 14, 2006; 113(6): 814 - 822. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. J. Barrett and P. S. Parfrey Preventing Nephropathy Induced by Contrast Medium N. Engl. J. Med., January 26, 2006; 354(4): 379 - 386. [Full Text] [PDF]
|
|
|
|
|
|
M.-R. Movahed, J. Wong, and S. Molloi Removal of Iodine Contrast From Coronary Sinus in Swine During Coronary Angiography J. Am. Coll. Cardiol., January 17, 2006; 47(2): 465 - 467. [Full Text] [PDF]
|
|
|
|
|
|
S. Detrenis, M. Meschi, S. Musini, and G. Savazzi Lights and shadows on the pathogenesis of contrast-induced nephropathy: state of the art Nephrol. Dial. Transplant., August 1, 2005; 20(8): 1542 - 1550. [Full Text] [PDF]
|
|
|
|
 |
|
 J. A. Brinker, C. J. Davidson, and W. Laskey Preventing in-hospital cardiac and renal complications in high-risk PCI patients Eur. Heart J. Suppl., August 1, 2005; 7(suppl_G): G13 - G24. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V O Gomes, C E Poli de Figueredo, P Caramori, R Lasevitch, L C Bodanese, A Araujo, A P Roedel, A P Caramori, F S Brito Jr, H G Bezerra, et al. N-acetylcysteine does not prevent contrast induced nephropathy after cardiac catheterisation with an ionic low osmolality contrast medium: a multicentre clinical trial Heart, June 1, 2005; 91(6): 774 - 778. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. C. Heinrich, M. K. Kuhlmann, A. Grgic, M. Heckmann, B. Kramann, and M. Uder Cytotoxic Effects of Ionic High-osmolar, Nonionic Monomeric, and Nonionic Iso-osmolar Dimeric Iodinated Contrast Media on Renal Tubular Cells in Vitro Radiology, June 1, 2005; 235(3): 843 - 849. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 I. Goldenberg and S. Matetzky Nephropathy induced by contrast media: pathogenesis, risk factors and preventive strategies Can. Med. Assoc. J., May 24, 2005; 172(11): 1461 - 1471. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. D. Weisbord and P. M. Palevsky Radiocontrast-Induced Acute Renal Failure J Intensive Care Med, March 1, 2005; 20(2): 63 - 75. [Abstract] [PDF]
|
|
|
|
 |
|
 J. L. Gross, M. J. de Azevedo, S. P. Silveiro, L. H. Canani, M. L. Caramori, and T. Zelmanovitz Diabetic Nephropathy: Diagnosis, Prevention, and Treatment Diabetes Care, January 1, 2005; 28(1): 164 - 176. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. G. Gleeson and S. Bulugahapitiya Contrast-Induced Nephropathy Am. J. Roentgenol., December 1, 2004; 183(6): 1673 - 1689. [Full Text] [PDF]
|
|
|
|
|
|
M. Maeder, M. Klein, T. Fehr, and H. Rickli Contrast nephropathy: Review focusing on prevention J. Am. Coll. Cardiol., November 2, 2004; 44(9): 1763 - 1771. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Marenzi, G. Lauri, E. Assanelli, J. Campodonico, M. De Metrio, I. Marana, M. Grazi, F. Veglia, and A. L. Bartorelli Contrast-induced nephropathy in patients undergoing primary angioplasty for acute myocardial infarction J. Am. Coll. Cardiol., November 2, 2004; 44(9): 1780 - 1785. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Spargias, E. Alexopoulos, S. Kyrzopoulos, P. Iacovis, D. C. Greenwood, A. Manginas, V. Voudris, G. Pavlides, C. E. Buller, D. Kremastinos, et al. Ascorbic Acid Prevents Contrast-Mediated Nephropathy in Patients With Renal Dysfunction Undergoing Coronary Angiography or Intervention Circulation, November 2, 2004; 110(18): 2837 - 2842. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. H. Ix, C. E. McCulloch, and G. M. Chertow Theophylline for the prevention of radiocontrast nephropathy: a meta-analysis Nephrol. Dial. Transplant., November 1, 2004; 19(11): 2747 - 2753. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Mehran, E. D. Aymong, E. Nikolsky, Z. Lasic, I. Iakovou, M. Fahy, G. S. Mintz, A. J. Lansky, J. W. Moses, G. W. Stone, et al. A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: Development and initial validation J. Am. Coll. Cardiol., October 6, 2004; 44(7): 1393 - 1399. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. D. Trachiotis, D. Hanumara, L. McKenna, P. Corso, and A. Pfister Surgical revascularization after acute myocardial infarction in patients with end-stage renal disease Eur. J. Cardiothorac. Surg., October 1, 2004; 26(4): 671 - 675. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. Goldenberg, M. Shechter, S. Matetzky, M. Jonas, M. Adam, H. Pres, D. Elian, O. Agranat, E. Schwammenthal, and V. Guetta Oral acetylcysteine as an adjunct to saline hydration for the prevention of contrast-induced nephropathy following coronary angiography: A randomized controlled trial and review of the current literature Eur. Heart J., February 1, 2004; 25(3): 212 - 218. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. W. Stone, P. A. McCullough, J. A. Tumlin, N. E. Lepor, H. Madyoon, P. Murray, A. Wang, A. A. Chu, G. L. Schaer, M. Stevens, et al. Fenoldopam Mesylate for the Prevention of Contrast-Induced Nephropathy: A Randomized Controlled Trial JAMA, November 5, 2003; 290(17): 2284 - 2291. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Marenzi, I. Marana, G. Lauri, E. Assanelli, M. Grazi, J. Campodonico, D. Trabattoni, F. Fabbiocchi, P. Montorsi, and A. L. Bartorelli The Prevention of Radiocontrast-Agent-Induced Nephropathy by Hemofiltration N. Engl. J. Med., October 2, 2003; 349(14): 1333 - 1340. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. J. Gruber, C. J. Shapiro, C. Braun, R. Birck, C. M. Bridges, V. S. Swaroop, M.-T. Cuddihy, P. Aspelin, and K. J. Berg Nephropathy Induced by Contrast Medium N. Engl. J. Med., May 29, 2003; 348(22): 2257 - 2259. [Full Text] [PDF]
|
|
|
|
|
|