Circulation. 2006;113:2031
(Circulation. 2006;113:2031.)
© 2006 American Heart Association, Inc.
Issue Highlights
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PHYSIOLOGICAL AND CLINICAL CONSEQUENCES OF RELIEF OF RIGHT VENTRICULAR OUTFLOW TRACT OBSTRUCTION LATE AFTER REPAIR OF CONGENITAL HEART DEFECTS, by Coats et al.
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Right ventricular outflow tract obstruction is a common problem
in patients with repaired congenital heart disease. Percutaneous
pulmonary valve implantation (PPVI) can treat this condition
without consequent pulmonary regurgitation or cardiopulmonary
bypass. Coats and colleagues studied the clinical and physiological
response to relieving right ventricular outflow tract obstruction,
without pulmonary regurgitation, with use of PPVI in 18 patients
with complex congenital heart defects. They found improvement
in symptoms, exercise tolerance, and ventricular function. The
use of PPVI permits, for the first time, investigation of the
early direct effects of relief of chronic right ventricular
pressure overload on cardiac function. Longer-term follow-up
is needed before PPVI can be recommended as a treatment for
right ventricular outflow tract obstruction. See p
2037.
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COFFEE CONSUMPTION AND CORONARY HEART DISEASE IN MEN AND WOMEN: A PROSPECTIVE COHORT STUDY, by Lopez-Garcia et al.
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The relation of coffee consumption to cardiovascular disease
has been the focus of intensive study, due in part to the ubiquitous
nature of coffee consumption and shops in Europe and North America.
In the present issue of
Circulation, Lopez-Garcia and colleagues
provide analyses of 2 large epidemiological data sets, the Health
Professionals Follow-up Study of 44 005 men and the Nurse’s
Health Study of 84 488 women, to shed further light on the topic.
With caffeine consumption habits updated periodically, the ability
to account for important confounders such as smoking, 1 to 2
decades of follow-up, and over 4000 cases of incident coronary
heart disease, the investigators found that caffeine was not
associated with increased risk of coronary heart disease. Similarly,
they found no association between decaffeinated coffee or tea
consumption and coronary heart disease events, and no association
between caffeine consumption and blood lipid levels. The study
provides convincing evidence against the hypothesis that caffeine
consumption predisposes to coronary heart disease. See p
2045.
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FEATURES OF THE METABOLIC SYNDROME AND DIABETES MELLITUS AS PREDICTORS OF AORTIC VALVE CALCIFICATION IN THE MULTI-ETHNIC STUDY OF ATHEROSCLEROSIS, by Katz et al.
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Aortic valve calcification is highly prevalent among persons
over 65 years of age. It is associated with a greater likelihood
of progression to aortic stenosis and 50% increased risk for
cardiovascular mortality. Accordingly, identification of factors
that promote aortic valve calcification may eventually lead
to the development of interventions that may prevent or retard
this process. Aortic valve calcification shares many histopathological
properties with those of atherosclerotic lesions. In this issue
of
Circulation, Katz and colleagues evaluate 6780 persons in
the Multi-Ethnic Study of Atherosclerosis (MESA) to determine
whether components of the metabolic syndrome that are known
to be associated with atherosclerosis are also associated with
increased aortic valve calcification. Their important findings
should serve as a strong foundation to stimulate future research
on the prevention of calcific aortic valve disease. See p
2113.
Visit http://circ.ahajournals.org:
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Clinician Update
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Inflammation in Atherosclerosis: Some Thoughts About Acute Coronary
Syndromes. See p
e728.
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Images in Cardiovascular Medicine
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Stereolithographic Biomodeling of Congenital Heart Disease by
Multislice Computed Tomography Imaging. See p
e733.
Implantation of Drug-Eluting Stent for the Coronary Artery Stenosis of Takayasu’s Arteritis: De Novo and In-Stent Restenosis. See p e735.
Pheochromocytoma-Related Cardiomyopathy: Inverted Takotsubo Contractile Pattern. See p e738.
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Book Review
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Carotid Artery Stenosis. See p
e740.
Related Articles:
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Inflammation in Atherosclerosis: Some Thoughts About Acute Coronary Syndromes
- Alexandra R. Lucas, Renee Korol, and Carl J. Pepine
Circulation 2006 113: e728-e732.
[Extract]
[Full Text]
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Stereolithographic Biomodeling of Congenital Heart Disease by Multislice Computed Tomography Imaging
- Isao Shiraishi, Yo Kajiyama, Masaaki Yamagishi, and Kenji Hamaoka
Circulation 2006 113: e733-e734.
[Extract]
[Full Text]
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Implantation of a Drug-Eluting Stent for the Coronary Artery Stenosis of Takayasu Arteritis: De Novo and In-Stent Restenosis
- Woong Chol Kang, Seung Hwan Han, Kyu Jin Oh, Tae Hoon Ahn, and Eak Kyun Shin
Circulation 2006 113: e735-e737.
[Extract]
[Full Text]
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Pheochromocytoma-Related Cardiomyopathy: Inverted Takotsubo Contractile Pattern
- Angel Sanchez-Recalde, Olga Costero, José M. Oliver, Cristian Iborra, Elena Ruiz, and José A. Sobrino
Circulation 2006 113: e738-e739.
[Extract]
[Full Text]
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Carotid Artery Stenosis
- J. Philip Kistler
Circulation 2006 113: e740-e741.
[Extract]
[Full Text]
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Physiological and Clinical Consequences of Relief of Right Ventricular Outflow Tract Obstruction Late After Repair of Congenital Heart Defects
- Louise Coats, Sachin Khambadkone, Graham Derrick, Shankar Sridharan, Silvia Schievano, Bryan Mist, Rod Jones, John E. Deanfield, Denis Pellerin, Philipp Bonhoeffer, and Andrew M. Taylor
Circulation 2006 113: 2037-2044.
[Abstract]
[Full Text]
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Features of the Metabolic Syndrome and Diabetes Mellitus as Predictors of Aortic Valve Calcification in the Multi-Ethnic Study of Atherosclerosis
- Ronit Katz, Nathan D. Wong, Richard Kronmal, Junichiro Takasu, David M. Shavelle, Jeffrey L. Probstfield, Alain G. Bertoni, Matthew J. Budoff, and Kevin D. O’Brien
Circulation 2006 113: 2113-2119.
[Abstract]
[Full Text]
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Coffee Consumption and Coronary Heart Disease in Men and Women: A Prospective Cohort Study
- Esther Lopez-Garcia, Rob M. van Dam, Walter C. Willett, Eric B. Rimm, JoAnn E. Manson, Meir J. Stampfer, Kathryn M. Rexrode, and Frank B. Hu
Circulation 2006 113: 2045-2053.
[Abstract]
[Full Text]
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