Files in this Data Supplement:

• Supplemental Methods - (Adobe PDF) (151 kb)
• Figure I - (TIFF) (3.23 MB) Role of Id2 heterozygousity in Ang II-induced target organ damage. (A) Telemetric mean arterial blood pressure (MAP) recording during week 12 of age. (B) Cardiac hypertrophy index (week 12). No difference in 24-hour albuminuria (C) and renal fibronectin expression (D) at the age of 12 weeks in Id2^+/- and Id2^-/- mice.
• Figure II - (TIFF) (3.59 MB) Renal expression of RAS components. Untreated and Ang II-infused Id2^+/- and Id2^-/- mice show similar renal AT1_A, AT1_B receptor and ATRAP expression. No differences could be found in AT2 receptor and ACE-2 expression.
• Figure III - (TIFF) (1.06 MB) Renal PPAR-α ƒnexpression. No differences could be detected in the four groups for PPAR-αƒnexpression.