Expanding Spectrum of Human RYR2-Related Disease: New Electrocardiographic, Structural, and Genetic Features
Circulation Bhuiyan et al.
116: 1569
Data Supplement
Files in this Data Supplement:
- Figure
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(TIF File) (12 MB). MLPA based deletion/duplication analysis of the RYR2. The column heights represent the dosage of the respective segments in the genomic DNA with two alleles (value of approx. 1 corresponds to two alleles). The two-allele dosage for RYR2 exon 3 (marked by arrow) was found in the range of 0.5. The control fragments and rest of the fragments from Desmoplakin, Plakophilin-2, RYR2, TGFâ3 and Plakoglobin are near the value of approx. 1, which corresponds to two alleles.
- Table
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(TIF file) (13 MB). List of the MLPA probes used to delineate the deletion.