Reversal of Global Apoptosis and Regional Stress Kinase Activation by Cardiac Resynchronization
Circulation Chakir et al.
117: 1369
Data Supplement
Files in this Data Supplement:
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(Microsoft PowerPoint Doc) (923 KB). Supplemental Figure I. A: Regional differences in JNK and ERK1/2 MAPK expression in DHF versus CRT ventricles. JNK was more expressed in the lateral wall, and ERK1/2 in the septum in DHF ventricles. Both were rendered more homogeneous by CRT. Summary densitometry results are shown below.
Supplemental Figure II. Comparison of protein expression in septal and lateral myocardium ((ep – epicardium; en-endocardium) for CamKII (GAPDH control), and phospho-MAK kinases (Calsequestran control) from example normal hearts. There were no differences between regions. Summary results below are from 6-8 different hearts.