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• Figure I - (Adobe Acrobat) (213 KB). COX-1 protein content in myocardium after iNOS gene transfer. Both nontransgenic (NTg) and IκBα^S32A,S36A transgenic (IκBα^S32A,S36A Tg) mice received Av3/LacZ or Av3/iNOS gene transfer 3 days prior to immunoblotting analyses. The kidney served as a positive control for COX-1 protein expression. There was no change in COX-1 protein levels in the transduced myocardium after iNOS gene transfer either in NTg or IκBα^S32A,S36A Tg mice (n=4/group). Assays were performed in triplicate.
• Figure II - (Adobe Acrobat) (386 KB). COX-2 protein content in lung, liver, spleen, and kidney after intramyocardial iNOS gene transfer. NTg, nontransgenic mice; IκBα^S32A,S36ATg, IκBα^S32A,S36A transgenic mice (n=6/group). Assays were performed in duplicate.