Mutations in the Gene Encoding Filamin A as a Cause for Familial Cardiac Valvular Dystrophy
Circulation Kyndt et al.
115: 40
Data Supplement
Files in this Data Supplement:
- Figure
-
(Power Point) (56.5 KB) Pedigree structure and fine mapping of the centromeric and the telomeric boundaries of the XMVD gene region. Pedigree structure and selected informative members of family 1a and 1b are shown. Females are designated by circles and males are designated by squares. Affected status is indicated by filled symbols, persons with no clinical manifestations of XMVD by unfilled symbols and hatched symbols indicate persons with undetermined status. Obligatory carriers are designated by black dots within female symbols. Slashes denote deceased family members. Boxed genotypes indicate the disease haplotype and arrows indicate recombinations.
- Table
-
(Excel) (24 KB) Two-point LOD scores for family 1a and 1b, obtained at different recombination fractions (Θ = 0, 0.05, 0.1, 0.15, 0.2, 0.25, 0.3, 0.35, 0.4, 0.45) for 8 markers on Xq28. Zmax represents the maximum lod score.