Files in this Data Supplement:

• Movie I - (MPEG) (2.12 MB) Initiation sequence resulting in spiral wave with drift. The figure below shows the location of the stimulus electrodes (in yellow). The color bar on the left indicates the color coding of the optical signal (blue is polarized at rest, red is depolarized). The trace on the bottom is the signal from the recording site indicated by the white square. The vertical white line in the trace indicates the time corresponding to the movie frame being displayed, and the time index (in seconds) of the movie frame is shown in the upper left. This movie was provided courtesy of Josh Cysyk.
• Movie II - (MPEG) (2.21 MB) Initiation sequence near a 1.90mm hole. The figure below shows the location of the hole (in white) and stimulus electrodes (in yellow).
• Movie III - (MPEG) (3.68 MB) Initiation sequence near a 1.90mm hole. The figure below shows the location of the hole (in white) and stimulus electrodes (in yellow). In this example, the spiral wave is attached to the hole.
• Movie IV - (MPEG) (5.85 MB) Ongoing spiral wave, before addition of lidocaine. Hole size is 1.13mm. Playback speed is 2 1/2 times slower than for Movies I--III.
• Movie V - (MPEG) (4.73 MB) Same spiral wave as in movie4, after addition of 90 ìM lidocaine. Playback speed same as in Movie IV.
• Movie VI - (MPEG) (6.05 MB) Same spiral wave as in movie5, after lidocaine washout. Playback speed same as in Movie IV.