Circulation. 1995;92:152-153
(Circulation. 1995;92:152-153.)
© 1995 American Heart Association, Inc.
American Heart Association National Research Awards
New Programs for 1996
R. Sanders Williams, MD
From the University of Texas Southwestern Medical Center,
Dallas.
Correspondence to R. Sanders Williams, MD, University of Texas
Southwestern Medical Center, 5323 Harry Hines Blvd, NB11.200, Dallas, TX
75235-8573.
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Introduction
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The National Research Committee of the
American Heart Association
(AHA) is responsible for determining the
characteristics of
research awards offered by the AHA National Center,
which recently
have totaled approximately $50 million annually,
and for the
peer review process that selects awardees. This committee
is
composed of representatives from each of the 14 Scientific Councils
and
6 at-large members, each of whom serves a 5-year nonrecurring
term.
Members of the Research Committee usually have been recipients
of AHA
research awards and almost always have served previously
in peer review
capacities for AHA affiliates, the National Center,
and the NIH. Most
Research Committee members are current department
or division directors
within their respective institutions.
For more than a year, as a component of an initiative called
"Preparing for the 21st Century" that touches on all aspects of
AHA activities, the National Research Committee has been reviewing its
current portfolio of research awards and considering alternatives for
the future. In this endeavor, we have sought and received input from
many AHA volunteers and staff working in both national and affiliate
programs.
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New Programs for 1996
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This process culminated in March 1995 with Research Committee
approval
of a complete revision of the research programs offered by the
AHA
National Center. These changes will not affect applications
received
in 1995 but will become effective for applications received
in
1996 and awards beginning in 1997. At that time, all of the
current
programsEstablished Investigator Award, Clinician-Scientist
Award,
Minority Scientist Development Award, Grant-in-Aid, and
Medical Student
Research Fellowshipwill be replaced by
three new types of grants, as
follows.
1. The Scientist Development Grant is a completely new
program, targeted at beginning investigators. This 4-year grant will
provide $65 000 annually, including up to $30 000 for salary and
fringe benefits, with the remainder devoted to project support.
Applications may be submitted in the final year of a postdoctoral
fellowship or within the first 4 years of a faculty appointment. Peer
review criteria will include originality and scientific merit of the
proposed project (which cannot overlap with other funded work), prior
productivity of the applicant, and evidence that the award will promote
independent status for the applicant. This grant program will supplant
the existing Clinician-Scientist and Minority Scientist Development
Awards. We anticipate awarding approximately 70 of these grants in
1997.
2. The Established Investigator Grant, a 4-year award, will
provide $75 000 annually, including up to $35 000 for salary and
fringe benefits, with the remainder devoted to project support. The
applicant pool will be similar to the existing Established Investigator
program, targeting investigators between 4 and 9 years beyond their
first faculty appointment. Peer review criteria will require that
successful applicants have demonstrated outstanding progress in leading
an independent research program, and they must propose an original
project of high scientific merit. Unlike the existing Established
Investigator Award, the proposed project can have no scientific overlap
with other projects funded by NIH or other sources. We anticipate
awarding approximately 50 of these grants in 1997.
3. The new Grant-in-Aid program will be similar to the
existing Grant-in-Aid but with several important differences. First,
more substantial projects can be proposed, with up to $55 000 in
annual support for up to 3 years, including 10% institutional overhead
costs. No salary support for the investigator is provided. Second,
unlike our current policy, there will be no restrictions on eligibility
based on seniority or academic rank. The emphasis in peer review will
be on innovation, originality, and potential impact of new research
directions. We anticipate awarding approximately 100 of these grants in
1997.
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Rationale for Changes in the National Center Research Portfolio
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This revised set of research programs was developed to utilize
the
limited pool of available funds most effectively in support
of the
mission of the AHA. The Research Committee has been concerned
for
several years that beginning investigators are particularly
vulnerable
to the currently restricted availability of research
support from the
NIH. Traditionally, the AHA has maintained
a special interest in
supporting young scientists who might
otherwise be unable to continue
in research careers. For the
past 2 years, we restricted the
Grant-in-Aid program to junior
investigators as a stopgap measure to
meet this need, but the
new AHA Scientist Development Award provides a
more satisfying
and definitive approach.
With the needs of beginning investigators covered by the AHA Scientist
Development Grant, we were then free to open up the Grant-in-Aid
program without restriction so as to solicit the best possible projects
from the entire research community. The revised Established
Investigator Grant should free institutions and investigators from the
frequently awkward situation encountered when the proposed project for
an Established Investigator award overlaps with NIH support. In all
three programs, larger awards focus resources on a somewhat smaller
number of awardees but provide more substantial support. This proposed
approach appears sound in the face of current realities with respect to
federal support for biomedical research.
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Support for Physician-Scientists and Underrepresented Minorities
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The termination of the Clinician-Scientist and Minority Scientist
Development
Awards should not be interpreted as a retreat from the
long-standing
goals of the AHA in supporting physician-scientists and
in promoting
inclusiveness in our research programs. We believe that
both
of these goals can be met more effectively through the new
portfolio.
With respect to physician-scientists who previously would
have
been eligible for the Clinician-Scientist Award, we expect the
number
of AHA Scientist Development Awards to be sufficient to support
an
equal or greater number of such individuals. We will monitor
the
reality of this prediction over time, and the special perspectives
provided
by physician-scientists will continue to be considered in the
composition
of peer review committees.
We expect these new programs to provide greater opportunities for
underrepresented minorities to receive research support from the AHA,
despite the discontinuation of the Minority Scientist Development Award
program. As a tangible step toward increasing the involvement of
minority investigators, the National Research Committee voted to set a
floor of 6% of all funds invested through these three new programs for
funding applications from underrepresented minority scientists.
Applications from minority investigators will be evaluated and scored
in the common pool, but funding decisions will include this criterion.
The AHA Scientist Development Grant should prove particularly helpful
to female and minority investigators, since we expect such individuals
to be more highly represented among younger as opposed to older
applicants.
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Relations Between National Center and AHA Affiliate Research
Programs
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These decisions on the part of the National Research Committee
concern
only that portion of AHA research dollars (currently about
50%)
that are administered through the National Center. An additional
$50
million in annual research support is currently provided from
the
55 AHA affiliate organizations around the country, each
of which
determines the manner in which their affiliate research
funds are used.
In principle, the overall mission of the AHAthe
reduction of
disability and death from cardiovascular diseases
and strokeis best
served when National Center and affiliate
research programs serve
complementary needs and work together
to support those projects and
individuals most likely to serve
that mission.
The structure of these new national research programs has been strongly
influenced by comments received from AHA affiliate volunteers and
staff, and we continue to welcome such input. We also hope that
decisions made by the National Research Committee will influence
actions taken by affiliates with respect to their own research
programs. For example, the trend toward more substantial awards and a
tighter focus on projects of the highest merit seems appropriate and
necessary in these leaner times, and these principles have been
strongly supported by the Research Program and Evaluation Committee,
the volunteer committee within the AHA charged with oversight of the
entire research enterprise, including both the National Center and AHA
affiliates. Several affiliates already have endorsed the new set of
programs from the National Center and are seeking to structure their
local research portfolios in a complementary manner.
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Other Changes and Future Plans
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Beginning with applications received in 1995, national AHA
peer
review committees no longer will provide written critiques to
unsuccessful
applicants. This decision was based primarily on the need
to
keep costs of peer review at a minimum while maintaining the
highest
standards of quality in evaluating increasingly large
numbers of
applications. The Research Committee also is conducting
trials of
several methods for identifying less meritorious applications
through
some form of preliminary review (triage). In addition,
other changes in
the peer review system that would reduce the
time elapsed between
submission of the proposal and notification
of awards to successful
applicants are under consideration.
These policy changes and the new research programs to be launched
in 1996 will be subjected to the same ongoing scrutiny with which the
Research Committee has monitored past and current national AHA research
programs. Comments and suggestions from the cardiovascular research
community are welcomed and are most appropriately channeled through
your Council representatives.
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Footnotes
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Dr Williams is immediate past chairman of the AHA National Research
Committee.