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(Circulation. 2008;118:e689.)
© 2008 American Heart Association, Inc.

Correspondence

Response to Letter Regarding Article, "Association of Leukocyte Telomere Length With Circulating Biomarkers of the Renin-Angiotensin-Aldosterone System: The Framingham Heart Study"

Ramachandran S. Vasan, MD; Serkalem Demissie, PhD; L. Adrienne Cupples, PhD; Emelia J. Benjamin, MD, ScM

National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Mass

Charles White, MPH

Department of Biostatistics, Boston University School of Public Health, Boston, Mass

Masayuki Kimura; Jeffrey P. Gardner; Xiaogian Cao; Abraham Aviv, MD

Center of Human Development and Aging, University of Medicine and Dentistry of New Jersey, Newark, NJ

Nader Rifai, PhD

Center for Cardiovascular Disease Prevention, Brigham and Women’s Hospital, Harvard Medical School, Boston, Mass

Thomas J. Wang, MD

Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Mass

Daniel Levy, MD

National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md

We would like to thank Dr Huzen and colleagues for their suggestion. Indeed, we are conducting several additional analyses relating telomere length to other markers of the renin-angiotensin-aldosterone system and related pathways, including relating telomere length to measures of left ventricular hypertrophy. We deemed it beyond the scope of the original article¹ to present a comprehensive analysis of multiple phenotypes and chose to focus on direct markers of the renin-angiotensin-aldosterone system as reflected by circulating biomarkers.

	Acknowledgments

 
Disclosures

None.

	Reference

Top Reference

 
1. Vasan RS, Demissie S, Kimura M, Cupples LA, Rifai N, White C, Wang TJ, Gardner JP, Cao X, Benjamin EJ, Levy D, Aviv A. Association of leukocyte telomere length with circulating biomarkers of the renin-angiotensin-aldosterone system: the Framingham Heart Study. Circulation. 2008; 117: 1138–1144.[Abstract/Free Full Text]

This Article Extract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Vasan, R. S. Articles by Levy, D. Search for Related Content PubMed Articles by Vasan, R. S. Articles by Levy, D. Related Collections Epidemiology