| Prosthetic cardiac valve or prosthetic material used for cardiac valve repair |
| Previous IE |
| Congenital heart disease (CHD)* |
| Unrepaired cyanotic CHD, including palliative shunts and conduits |
Completely repaired congenital heart defect with prosthetic material or device, whether placed by surgery or by catheter intervention, during the first 6 months after the procedure |
| Repaired CHD with residual defects at the site or adjacent to the site of a prosthetic patch or prosthetic device (which inhibit endothelialization) |
| Cardiac transplantation recipients who develop cardiac valvulopathy |
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| *Except for the conditions listed above, antibiotic prophylaxis is no longer recommended for any other form of CHD. |
Prophylaxis is reasonable because endothelialization of prosthetic material occurs within 6 months after the procedure. |