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Circulation
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Table 3. Cardiac Conditions Associated With the Highest Risk of Adverse Outcome From Endocarditis for Which Prophylaxis With Dental Procedures Is Reasonable
Prosthetic cardiac valve or prosthetic material used for cardiac valve repair
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Congenital heart disease (CHD)*
    Unrepaired cyanotic CHD, including palliative shunts and conduits
    Completely repaired congenital heart defect with prosthetic material or device, whether placed by surgery or by catheter intervention, during the first 6 months after the procedure{dagger}
    Repaired CHD with residual defects at the site or adjacent to the site of a prosthetic patch or prosthetic device (which inhibit endothelialization)
Cardiac transplantation recipients who develop cardiac valvulopathy

*Except for the conditions listed above, antibiotic prophylaxis is no longer recommended for any other form of CHD.
{dagger}Prophylaxis is reasonable because endothelialization of prosthetic material occurs within 6 months after the procedure.





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