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Circulation. 2006;114:97

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(Circulation. 2006;114:97.)
© 2006 American Heart Association, Inc.

Issue Highlights


*    SECULAR TRENDS IN INCIDENCE OF ATRIAL FIBRILLATION IN OLMSTED COUNTY, MINNESOTA, 1980 TO 2000, AND IMPLICATIONS ON THE PROJECTIONS FOR FUTURE PREVALENCE, by Miyasaka et al.
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Atrial fibrillation (AF) is a growing public health problem that is associated with increased risk of stroke, heart failure, and death. The prevalence of AF in the community in the United States has increased over the last 4 decades, but the contributing reasons remain far from clear. In this issue of Circulation, Miyasaka and colleagues analyze data from the predominantly white population of Olmsted County, Minnesota, to assess secular trends in incidence of AF over a 20-year period (1980–2000). The age- and sex-adjusted incidence of AF increased in both sexes (overall 12.6% increase) over this time period. An increase in burden of obesity during this time period in Olmsted County likely contributed to the increase in AF incidence. Based on these incidence trends, the authors project that the number of individuals with prevalent AF in the United States will increase 3-fold by 2050 (exceeding 10 million), underscoring the importance of preventing AF by controlling risk factors for the condition. See p 119.


*    GEOMETRIC DETERMINANTS OF FUNCTIONAL TRICUSPID REGURGITATION: INSIGHTS FROM 3-DIMENSIONAL ECHOCARDIOGRAPHY, by Ton-Nu et al.
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Contemporary noninvasive imaging modalities are enabling the in vivo study and quantitative evaluation of complex cardiovascular anatomy and physiology. A novel example of this approach is examined in this issue of Circulation by Ton-Nu and colleagues. Using real-time 3-dimensional echocardiography, the authors examined tricuspid valve morphology in patients with functional tricuspid regurgitation, compared with a reference group with normal tricuspid valve function. They quantitate the complex shape of the normal annulus and the saddle-shaped tricuspid valve and describe the changes in the annular size and shape as well as flattening of the valve in those with regurgitation and the relation to the degree of regurgitation. These data will inform future efforts to optimize tricuspid valve and annular repair. See p 143.


*    HEALTHY LIFESTYLE FACTORS IN THE PRIMARY PREVENTION OF CORONARY HEART DISEASE AMONG MEN: BENEFITS AMONG USERS AND NONUSERS OF LIPID-LOWERING AND ANTIHYPERTENSIVE MEDICATIONS, by Chiuve et al.
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Although healthy lifestyle behaviors are recommended to improve individual coronary heart disease (CHD) risk factors and reduce CHD events, the impact of adherence to a healthy lifestyle on the overall burden of CHD is not known. In this issue of Circulation, Chiuve et al present compelling, prospective, observational data on 42 847 middle-aged men in the Health Professionals Follow-up Study relative to their smoking, diet and alcohol intake, weight, and participation in regular exercise. Data on men who are taking medications to control hypertension and lipids are also analyzed. These important findings provide strong evidence to encourage the adoption of a healthy lifestyle as the foundation for CHD prevention and should influence medical practice as well as healthcare policy. See p 160.

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*    Clinician Update
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Acute Pulmonary Embolism: Part I: Epidemiology and Diagnosis. See p e28.


*    Images in Cardiovascular Medicine
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Contrast Echocardiography in Apical Hypertrophic Cardiomyopathy. See p e33.

In Vivo Imaging of the Adult Drosophila melanogaster Heart With Real-Time Optical Coherence Tomography. See p e35.

Large Cardiac Varix Associated With Stroke. See p e37.


Figure 13916
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*    Book Review
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Cardiac CT, PET and MR. See p e39.


*    Correspondence
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See p e40.





This Article
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