Circulation. 2006;113:2261
(Circulation. 2006;113:2261.)
© 2006 American Heart Association, Inc.
Issue Highlights
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SECULAR TRENDS IN DEATHS FROM CARDIOVASCULAR DISEASES: A 25-YEAR COMMUNITY STUDY, by Gerber et al.
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Age-adjusted cardiovascular disease mortality has dropped over
the last few decades, but questions remain about whether there
are differences in the rate of decline by the site of death
(in-hospital or out-of-hospital) and by age and sex. The population
of Olmsted County, Minn—the home of the Mayo Clinic—has
provided investigators an opportunity to track these changes
over 25 years, from 1979 through 2003, in a group with a fairly
uniform medical care system. The study provides important public
health information about the progress that is being made in
the prevention of cardiovascular death and highlights where
that progress may be lagging. See p
2285.
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PREDICTIVE FACTORS OF RESTENOSIS AFTER CORONARY IMPLANTATION OF SIROLIMUS- OR PACLITAXEL-ELUTING STENTS, by Kastrati et al.
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Although clinical trials have established that drug-eluting
stents improve clinical outcomes after percutaneous coronary
intervention, it is valuable to examine real-world experience
with new devices after approval, in this case to define the
optimal utility of drug-eluting stents in broader patient and
lesion subsets. In this issue of
Circulation, Kastrati et al
identified predictive factors for angiographic and clinical
restenosis after the implantation of drug-eluting stents in
1845 patients with 2093 lesions. Multivariable analysis showed
that vessel size, final diameter stenosis, and drug-eluting
stent type (lower with Cypher compared to TAXUS) were the strongest
predictors of restenosis. These findings may prove useful in
improving clinical outcomes after implantation of drug-eluting
stents. See p
2293.
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PERCUTANEOUS SEPTAL SINUS SHORTENING: A NOVEL PROCEDURE FOR THE TREATMENT OF FUNCTIONAL MITRAL REGURGITATION, by Rogers et al.
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Left ventricular remodeling in the setting of heart failure
can lead to dilation of the mitral valve annulus and functional
mitral regurgitation. In the current issue of
Circulation, Rogers
and colleagues describe a novel percutaneous technique to treat
this condition in an ovine model of pacing-induced heart failure.
The method involves progressive tensioning of a bridge element
that connects devices placed in the great cardiac vein and on
the right side of the atrial septum, reducing the dimension
of the mitral valve orifice. Short-term and 30-day evaluation
demonstrated the feasibility of percutaneous device implantation,
reduction in the severity of mitral regurgitation, and hemodynamic
improvement. This proof-of-concept study may provide a rationale
for clinical trials using this approach. See p
2329.
Visit http://circ.ahajournals.org:
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Clinician Update
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Electrocardiogram: Still the Cardiologist’s Best Friend.
See p
e753.
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Images in Cardiovascular Medicine
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Complete Ectopia Cordis. See p
e757.
Left Ventricular Hypertrophy and Outflow Tract Obstruction in a Patient With Anorexia Nervosa. See p e759.
Takotsubo Cardiomyopathy. See p e762.
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Book Review
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Microvascular Research: Biology and Pathology. See p
e763.
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Correspondence
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See p
e765.
Related Articles:
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Electrocardiogram: Still the Cardiologist’s Best Friend
- Shlomo Stern
Circulation 2006 113: e753-e756.
[Extract]
[Full Text]
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Complete Ectopia Cordis
- Christian Lilje, Florian Weiss, F. Lacour-Gayet, K. Ntalakoura, Vit Rázek, and J. Weil
Circulation 2006 113: e757-e758.
[Extract]
[Full Text]
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Left Ventricular Hypertrophy and Outflow Tract Obstruction in a Patient With Anorexia Nervosa
- Hideaki Senzaki, Makiko Kurihara, Satoshi Masutani, Nozomu Sasaki, Shunei Kyo, and Yuji Yokote
Circulation 2006 113: e759-e761.
[Extract]
[Full Text]
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Takotsubo Cardiomyopathy
- Dipak P. Shah, Lissa Sugeng, Sascha N. Goonewardena, Patrick Coon, and Roberto M. Lang
Circulation 2006 113: e762.
[Extract]
[Full Text]
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Microvascular Research: Biology and Pathology
- Richard P. Shannon
Circulation 2006 113: e763-e764.
[Extract]
[Full Text]
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Letter Regarding Article by Tomic et al, "Transcriptomic and Proteomic Patterns of Systemic Inflammation in On-Pump and Off-Pump Coronary Artery Bypass Grafting"
- Michael J. O’Dwyer, Edel Duggan, and Thomas Ryan
Circulation 2006 113: e765.
[Extract]
[Full Text]
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Secular Trends in Deaths From Cardiovascular Diseases: A 25-Year Community Study
- Yariv Gerber, Steven J. Jacobsen, Robert L. Frye, Susan A. Weston, Jill M. Killian, and Véronique L. Roger
Circulation 2006 113: 2285-2292.
[Abstract]
[Full Text]
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Percutaneous Septal Sinus Shortening: A Novel Procedure for the Treatment of Functional Mitral Regurgitation
- Jason H. Rogers, John A. Macoviak, David A. Rahdert, Patricia A. Takeda, Igor F. Palacios, and Reginald I. Low
Circulation 2006 113: 2329-2334.
[Abstract]
[Full Text]
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Predictive Factors of Restenosis After Coronary Implantation of Sirolimus- or Paclitaxel-Eluting Stents
- Adnan Kastrati, Alban Dibra, Julinda Mehilli, Sandra Mayer, Susanne Pinieck, Jürgen Pache, Josef Dirschinger, and Albert Schömig
Circulation 2006 113: 2293-2300.
[Abstract]
[Full Text]
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SECULAR TRENDS IN DEATHS...
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