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Figure 2. Effect of Ad-APN treatment on atherosclerotic lesions in apoE-/- mice 5 days after recombinant adenovirus injection. A, Immunohistochemical detection of adiponectin, Mac-1, 
-actin, and Oil Red O staining in atherosclerotic lesions. Serial cross-section (1 0µm each) of the representative lesions in aortic sinus are shown (bar=100 µm). B, The mRNA levels of VCAM-1, SR-A, TNF-, and CD36 in aortic tissue in Ad-ßgal or Ad-APN–treated mice (n=5 each). The values are mean±SEM.
