Donate Help Contact The AHA Sign In Home
American Heart Association
Circulation
Search: search_blue_button Advanced Search
Circulation. 2001;104:2158-2163
doi: 10.1161/hc4301.098254
This Article
Right arrow Abstract Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Zheng, Z.-J.
Right arrow Articles by Mensah, G. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Zheng, Z.-J.
Right arrow Articles by Mensah, G. A.
Right arrowPubmed/NCBI databases
Medline Plus Health Information
*Cardiac Arrest
Related Collections
Right arrow Restenosis
Right arrow Catheter-based coronary interventions: stents

(Circulation. 2001;104:2158.)
© 2001 American Heart Association, Inc.


Clinical Investigation and Reports

Sudden Cardiac Death in the United States, 1989 to 1998

Zhi-Jie Zheng, MD, PhD; Janet B. Croft, PhD; Wayne H. Giles, MD, MS; George A. Mensah, MD, FESC

From the Cardiovascular Health Branch, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Ga.

Correspondence to Dr Zhi-Jie Zheng, Cardiovascular Health Branch, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Hwy NE, Mailstop K-47, Atlanta, GA 30341-3717. E-mail zzheng{at}cdc.gov


*    Abstract
up arrowTop
*Abstract
down arrowIntroduction
down arrowMethods
down arrowResults
down arrowDiscussion
down arrowReferences
 
Background— Sudden cardiac death (SCD) is a major clinical and public health problem.

Methods and Results— United States (US) vital statistics mortality data from 1989 to 1998 were analyzed. SCD is defined as deaths occurring out of the hospital or in the emergency room or as "dead on arrival" with an underlying cause of death reported as a cardiac disease (ICD-9 code 390 to 398, 402, or 404 to 429). Death rates were calculated for residents of the US aged >=35 years and standardized to the 2000 US population. Of 719 456 cardiac deaths among adults aged >=35 years in 1998, 456 076 (63%) were defined as SCD. Among decedents aged 35 to 44 years, 74% of cardiac deaths were SCD. Of all SCDs in 1998, coronary heart disease (ICD-9 codes 410 to 414) was the underlying cause on 62% of death certificates. Death rates for SCD increased with age and were higher in men than women, although there was no difference at age >=85 years. The black population had higher death rates for SCD than white, American Indian/Alaska Native, or Asian/Pacific Islander populations. The Hispanic population had lower death rates for SCD than the non-Hispanic population. From 1989 to 1998, SCD, as the proportion of all cardiac deaths, increased 12.4% (56.3% to 63.9%), and age-adjusted SCD rates declined 11.7% in men and 5.8% in women. During the same time, age-specific death rates for SCD increased 21% among women aged 35 to 44 years.

Conclusions— SCD remains an important public health problem in the US. The increase in death rates for SCD among younger women warrants additional investigation.


Key Words: death, sudden • heart diseases • mortality • epidemiology


*    Introduction
up arrowTop
up arrowAbstract
*Introduction
down arrowMethods
down arrowResults
down arrowDiscussion
down arrowReferences
 
Sudden cardiac death (SCD) is the most common lethal manifestation of heart disease, and in many cases it is the descent‘ first and only symptom.13 The high incidence and sudden, unexpected nature, combining with the low successful rate of resuscitation, make SCD a major unsolved problem in clinical cardiology, emergency medicine, and public health.47 Clinical and pathologic findings suggest that patients with conditions such as coronary artery disease, cardiomyopathy, cardiac rhythm disturbances, or hypertensive heart disease are at high risk of SCD.8 In most cases, the mechanism of onset is a ventricular tachycardia that rapidly progresses to ventricular fibrillation and circulatory collapse.57,9

Clinically, SCD is the sudden, unexpected natural death from a cardiac cause a short time (generally <=1 hour) after the onset of symptoms in a person without any previous condition that would seem fatal.5,6 Unfortunately, such a definition is difficult to apply in the public health surveillance, because the death certificate often does not include the time of onset. As an alternative, Gillum and colleagues1012 have defined SCD as any cardiac death occurring out of the hospital or taking place in the emergency room or dead on arrival in the emergency room. This approach has reasonable validity13,14 and is useful for assessing population trends in SCD. The present study uses a similar approach with some modifications to characterize the epidemiologic features of SCD in residents of the United States (US) aged >=35 years and to describe the secular trend of SCD from 1989 to 1998.


*    Methods
up arrowTop
up arrowAbstract
up arrowIntroduction
*Methods
down arrowResults
down arrowDiscussion
down arrowReferences
 
US vital statistics mortality data compiled by the National Center for Health Statistics at the Centers for Disease Control and Prevention were used for analyses. Death certificates are processed in state vital statistics offices and then sent to the National Center for Health for entry into a detailed national mortality database file.15 Causes of death on the death certificate are reported by a physician, medical examiner, or coroner. Demographic information such as sex, age, and race is reported by funeral directors, usually from observation or information provided by family members. We defined a cardiac disease death as one for which the underlying cause of death was classified to ICD-9 code 390 to 398, 402, or 404 to 429. SCD was defined as a death that was reported as occurring out of hospital or in the emergency room or as "dead on arrival" with an underlying cause of death reported as cardiac disease.

All analyses were performed using SAS and were limited to US residents aged >=35 years because of the small number of younger cases (<1%). We also limited our analyses for 1989 and later because of the major change in the coding of place of death in death certificates in 1989. We assessed characteristics and trends in the proportions of cardiac deaths that were SCD, characteristics of persons suffering SCD in 1998, and trends in death rates for SCD from 1989 to 1998. Death rates for SCD were calculated for groups defined by calendar year, age (35 to 44, 45 to 54, 55 to 64, 65 to 74, 75 to 84, and >=85 years), sex, and race (white, black, American Indian/Alaska Native, and Asian/Pacific Islander). Hispanic origin has been reported on death certificates since 1978; since then, an increasing number of states have added this item. Because of large missing data in earlier years, the variable was used in 1998 analyses only. Denominators were the US Bureau of the Census mid-year estimates of the resident population for each group.16 Age-adjusted death rates were standardized by the direct method to the 2000 projected US population.17 Relative change in death rates for SCD from 1989 to 1998 was calculated as the 1998 rate minus the 1989 rate, divided by the 1989 rate, and multiplied by 100.


*    Results
up arrowTop
up arrowAbstract
up arrowIntroduction
up arrowMethods
*Results
down arrowDiscussion
down arrowReferences
 
In 1998, there were 719 456 cardiac disease deaths among US residents aged >=35 years, of which 456 076 (63.3%) were defined as SCD. The proportion of SCD among all cardiac deaths in 1998 did not differ substantially between men (62.9%) and women (63.8%). However, women had higher proportion of out-of-hospital cardiac deaths than men, whereas men had higher proportion of death occurring in the emergency room or as "dead on arrival" (Table 1). For younger ages (35 to 74 years), SCD as the proportion of all cardiac death was higher in men (66.6%) than women (57.2%). Overall, SCDs accounted for 74.4% of all cardiac disease deaths for ages 35 to 44 years; 72.7% for 45 to 54 years; 65.6% for 55 to 64 years; 58.0% for 65 to 74 years; 58% for 75 to 84 years; and 68.8% for >=85 years. In 1998, the proportions of cardiac deaths that occurred in hospital or out of hospital were generally higher for successive age groups; conversely, the proportion that occurred in the emergency room or were dead on arrival generally declined with age (Table 1).


View this table:
[in this window]
[in a new window]
 
Table 1. Distribution of Place of Death Among All Cardiac Disease Decedents Aged >=35 Years by Selected Characteristics in 1998 and Trend for 1989 to 1998: United States

SCD accounted for 63.7% of all cardiac deaths among whites; 62.0% among blacks; 60.5% among American Indians/Alaska Natives; and 55.2% among Asian/Pacific Islanders. The proportion of cardiac deaths that were SCD was higher among non-Hispanics than Hispanics (63.7% versus 54.5%). Whites had a greater proportion of cardiac deaths out of hospital than other groups, whereas blacks had the highest proportion of cardiac deaths occurring in the emergency room or as "dead on arrival" (Table 1).

SCD as the proportion of all cardiac deaths increased 12.4% from 1989 to 1998 (56.3% to 63.9%). The proportion of cardiac deaths that occurred in the emergency room or as "dead on arrival" decreased 9.7%, and the proportion of out-of-hospital SCD increased 23.5% (Table 1).

Of the 456 076 persons suffering SCD in 1998, 51.6% were women and 82.8% were aged >=65 years. The mean age of SCD victims was 70 years in men and 82.4 years in women. In 1998, coronary heart disease (ICD-9 410 to 414) was listed as the underlying cause on 62.2% of the death certificates. The distribution of underlying causes of death for SCD decedents varied between those aged 35 to 64 years and those aged >=65 years (Table 2). Acute ischemic heart disease (ICD-9 410 to 411), unspecified cardiovascular disease (ICD-9 429.2), and cardiomyopathy and dysrhythmias (ICD-9 425 to 427) were more common in the younger group. Chronic ischemic heart disease (ICD-9 412 to 414) and heart failure (ICD-9 428) were more frequent in the older group.


View this table:
[in this window]
[in a new window]
 
Table 2. Distribution of Underlying Cause of Death Among SCD Decedents Aged >=35 Years by Age Group: United States, 1998

As expected, age-specific death rates for SCD in 1998 increased with successive age groups and were higher in men (Table 3), although the gender difference narrowed in older groups and disappeared for ages >=85 years. The male to female ratio was 2.9 at 35 to 44 years; 3.4 at 45 to 54 years; 2.8 at 55 to 64 years; 2.1 at 65 to 74 years; 1.5 at 75 to 84 years; and 1 at >=85 years. The overall age-adjusted death rate for SCD was 50% higher in men than women (410.6 versus 274.6 per 100 000) in 1998. The black population had the highest age-adjusted rates, followed by white, American Indians/Alaska Native, and Asian/Pacific Islander populations (Table 3). Non-Hispanic adults had higher age-adjusted rates for SCD than did Hispanic adults.


View this table:
[in this window]
[in a new window]
 
Table 3. Number and Death Rates for SCD and Relative Change Since 1989 Among Adults Aged >=35 Years by Selected Characteristics: United States, 1998

Although SCD rates declined between 1989 and 1998 among men in all age groups, they increased 21.1% among women aged 35 to 44 years (Table 3). Overall, age-adjusted SCD rates declined 8.3% (11.7% in men and 5.8% in women) during this 10-year period. This decline was observed in all race groups among men (Figure 1) and in all but American Indian/Alaska Native women, who experienced declining SCD rates until 1996, with an increase in SCD rate in 1997 and 1998 (Figure 2).



View larger version (16K):
[in this window]
[in a new window]
 
Figure 1. Age-adjusted death rates (per 100 000 US population) for sudden cardiac death among men aged 35 years and older by race in the US from 1989 to 1990.



View larger version (16K):
[in this window]
[in a new window]
 
Figure 2. Age-adjusted death rates (per 100 000 US population) for sudden cardiac death among women aged 35 years and older by race in the US from 1989 to 1990.


*    Discussion
up arrowTop
up arrowAbstract
up arrowIntroduction
up arrowMethods
up arrowResults
*Discussion
down arrowReferences
 
Despite major advances in the prevention and medical treatment of cardiac diseases and improvements in emergency transport systems, we found that >60% of cardiac disease deaths continue to remain sudden. These 400 000 to 450 000 sudden cardiac deaths per year from 1989 to 1998 represent cardiac disease deaths that occur out of hospital, in the emergency room, or as "dead on arrival." The present surveillance data demonstrate a 10-year decline in the proportion of cardiac deaths that occurred in the hospital or in the emergency room or were dead on arrival at the emergency room but an alarming increase in the proportion that never made it to the hospital. This trend probably reflects aging of the US population and the later onset of sudden, fatal cardiac events in the elderly, who experience 83% of SCDs. Still, we found an increasing trend in the proportion of out-of-hospital cardiac death in all age groups. Thus, future efforts to reduce the burden of mortality from heart disease must address out-of-hospital deaths, which means better primary prevention, continued improvements in secondary prevention strategies, early recognition of symptoms and signs of heart disease, and more timely access to emergency cardiac care.

We found disturbing trends for women in this report: >50% of their cardiac deaths were out of hospital; their decline in SCD rates was much less than it was for men, and the rate for SCD increased 21% among women aged 35 to 44 years. The reasons for such disturbing trends are not known, and, thus, additional investigation is warranted. A variety of differences in awareness, risk factors, underlying etiology, symptoms and signs, and outcomes of cardiovascular disease may have played some roles. For example, in a recent study, >70% of women reported that they did not talk to their doctors about heart disease, and <10% considered it to be their greatest health concern.18 Women may receive less aggressive and more delayed treatment for heart disease than men,19,20 and they usually have a higher risk of death after heart attack, particularly young women.20,21 Furthermore, because the symptoms of heart disease in women are often atypical (eg, neck pain, back pain, jaw pain, or nausea) of chest pain, they may go unrecognized.22 In addition, reports have indicated that the risk factors for and pathophysiology of SCD may differ in younger versus older women. For example, younger women with SCD were more likely to be smokers, whereas older women had higher prevalence of hypercholesterolemia, hypertension, and diabetes2326; plaque erosion leading to acute coronary thrombosis is more common in younger women with SCD, whereas plaque rupture or healed myocardial infarction without acute coronary thrombosis was the dominant lesion among older women.23

Surveillance reports using death certificate data have several limitations. First, the cause of death is not validated by a medical record or autopsy verification. The reliability and accuracy of cause of death depends on the correctness of the diagnosis and accuracy with which the death certificate is completed by the physician, medical examiner, or coroner. A previous study indicated that coronary heart disease may be substantially over-represented as a cause of death on death certificates, with the consequence that national mortality statistics may have overestimated the frequency of coronary heart disease by up to 24%.27 Second, the consensus clinical definition of SCD in the US includes death within 1 hour of onset of symptoms as a major criterion,2,3,57,2426 although other criteria, such as death within 6 hours and 24 hours, were also used in other studies.28 Unfortunately, time of onset of disease symptoms and time of death are often not recorded on death certificates. However, studies involving retrospective physician review have reported that the validity of the underlying cause of death on the death certificate for out-of-hospital coronary heart disease deaths and SCD is high.13,14,29 Despite the potential of either misdiagnosis or misreporting of diagnosis, death certificate data remain useful and the only data source presently available to assess population and national trends in SCD, provided that the false-positive rate remains relatively constant over time. Ultimately, an improved national surveillance system or a national registry on SCD will be essential in providing better information on incidence, management, and outcomes and will help determine the success of clinical and public health interventions against cardiovascular disease in the population.

The validity of the reporting of race and Hispanic ethnicity on death certificates is another concern. To our knowledge, few studies have examined SCD in American Indian/Alaskan Native, Asian/Pacific Islander, or Hispanic populations in the US. In this report, we found that adults in these racial and ethnic groups had lower SCD death rates than white or black adults. Underreporting of American Indian/Alaska Native or Asian/Pacific Islander race or of Hispanic ethnicity on death certificates and census population counts may lead to underestimates of SCD in these groups and overestimates among white and black populations.3032 In addition, another limitation of surveillance report based on death certificate data is that we are unable to ascertain predisposing risk factors for SCDs other than age, race, ethnicity, and sex.

These limitations notwithstanding, this surveillance report is valuable for its provision of the most recently available statistics for SCD for the entire US adult population. Unlike case-control studies and hospital registries, the US death certificate data has sufficient numbers to allow comparisons of secular trends, sex, age, and race or ethnicity. In addition, this study differs from the previous reports that focused on sudden death attributable to coronary heart disease only2,3,1012,26 by including all cardiac disease, which may yield a more in-depth understanding of the etiology of sudden cardiac death in the US population.

The encouraging declines in the proportion of cardiac deaths occurring in the hospital or the emergency room or as "dead on arrival" may reflect the improvements in emergency services and more timely and appropriate treatment. However, the increased trend in SCD outside of the hospital indicates a need for public health initiatives to improve the early recognition of heart attack symptoms and signs. Educational and media efforts should specifically target women and younger adults, who may dismiss cardiac arrest as a problem of men and the elderly. According to the Rapid Early Action for Coronary Treatment Trial, although knowledge of chest pain as an important heart attack symptom is relatively high in the US, there are racial and gender variations in identifying correct symptoms and signs of heart disease.33 National efforts are needed to increase the proportion of the general public who recognize signs and symptoms of a heart attack and who are willing to participate in the "chain of survival," which includes dialing 911, attempting cardiac resuscitation, and using automated external defibrillators until emergency personnel arrive.34 Finally, the primary prevention of coronary heart disease should remain a major focus of public health. Physicians and other health care providers should never miss the opportunity during routine physical examinations to counsel patients, including apparently healthy young adults and women of all ages, about the importance of controlling high blood pressure and high cholesterol levels, smoking avoidance or cessation, weight management, regular physical activity, and a diet low in saturated fats and cholesterol and rich in fruits and vegetables.

In conclusion, SCD remains an important clinical and public health problem in the US. Increased death rates for SCD among younger women warrant additional investigation of their potential risk factors. Public health education and media efforts should target increased awareness of the symptoms and signs of cardiac arrest and should attempt to increase the numbers of bystanders trained and willing to initiate the "chain of survival."

Received June 25, 2001; accepted August 20, 2001.


*    References
up arrowTop
up arrowAbstract
up arrowIntroduction
up arrowMethods
up arrowResults
up arrowDiscussion
*References
 
1. Kuller L, Lilienfeld A, Fisher R. Epidemiological study of sudden and unexpected deaths due to arteriosclerotic heart disease. Circulation. 1966; 34: 1056–1068.[Abstract/Free Full Text]

2. Doyle JT, Kannel WB, McNamara PM, et al. Factors related to suddenness of death from coronary disease: combined Albany-Framingham studies. Am J Cardiol. 1976; 37: 1073–1078.[Medline] [Order article via Infotrieve]

3. Kannel WB, Schatzkin A. Sudden death: lessons from subsets in population studies. J Am Coll Cardiol. 1985; 5 (6 suppl): 141B–149B.

4. Lown B. Sudden cardiac death: the major challenge confronting contemporary cardiology. Am J Cardiol. 1979; 43: 313–328.[Medline] [Order article via Infotrieve]

5. Myerburg RJ, Castellanos A. Cardiac arrest and sudden cardiac death.In: Braunwald E, ed. Heart Disease: A Textbook of Cardiovascular Medicine. Philadelphia, Pa: WB Saunders; 1992: 756–789.

6. Zipes DP, Wellens HJ. Sudden cardiac death. Circulation. 1998; 98: 2334–2351.[Free Full Text]

7. Moss AJ. Prediction and prevention of sudden cardiac death. Ann Rev Med. 1980; 31: 1–14.[Medline] [Order article via Infotrieve]

8. Roberts WC. Sudden cardiac death: a diversity of causes with focus on atherosclerotic coronary artery disease. Am J Cardiol. 1990; 65: 13B–19B.[Medline] [Order article via Infotrieve]

9. Bayes de Luna A, Coumel P, Leclercq JF. Ambulatory sudden cardiac death: mechanisms of production of fatal arrhythmia on the basis of data from 157 cases. Am Heart J. 1989; 117: 151–159.[Medline] [Order article via Infotrieve]

10. Gillum RF, Folsom A, Luepker RV, et al. Sudden death and acute myocardial infarction in a metropolitan area, 1970–1980: the Minnesota Heart Survey. N Engl J Med. 1983; 309: 1353–138.[Abstract]

11. Gillum RF. Sudden coronary death in the United States: 1980–1985. Circulation. 1989; 79: 756–765.[Abstract/Free Full Text]

12. Gillum RF. Sudden cardiac death in Hispanic Americans and African Americans. Am J Public Health. 1997; 87: 1461–1466.[Abstract/Free Full Text]

13. Every NR, Parsons L, Hlatky MA, et al. Use and accuracy of state death certificates for classification of sudden cardiac deaths in high-risk populations. Am Heart J. 1997; 134: 1129–1132.[Medline] [Order article via Infotrieve]

14. Iribarren C, Crow RS, Hannan PJ, et al. Validation of death certificate diagnosis of out-of-hospital sudden cardiac death. Am J Cardiol. 1998; 82: 50–53.[Medline] [Order article via Infotrieve]

15. Murphy SL. Deaths: final data for 1998. Natl Vital Stat Rep. 2000; 48: 1–105.[Medline] [Order article via Infotrieve]

16. Deardorff K. US population estimates by age, sex, race and Hispanic origin: 1990 to 1997. United States Bureau of the Census, Current Population Report Series PPL-910. Washington, DC: US Government Printing Office; 1998.

17. Klein RJ, Schoenborn CA. Age adjustment using the 2000 projected US population: Healthy people 2010 statistical notes, No. 20. Hyattsville, Md: National Center for Health Statistics; 2001. DHHS Publication No. 2001-1237.

18. Mosca L, Jones WK, King KB, et al. Awareness, perception, and knowledge of heart disease risk and prevention among women in the United States: American Heart Association Women‘ Heart Disease and Stroke Campaign Task Force. Arch Fam Med. 2000; 9: 506–515.[Abstract/Free Full Text]

19. Schulman KA, Berlin JA, Harless W, et al. The effect of race and sex on physicians‘ recommendations for cardiac catheterization. N Engl J Med. 1999; 340: 618–626.[Abstract/Free Full Text]

20. Roger VL, Farkouh ME, Weston SA, et al. Sex differences in evaluation and outcome of unstable angina. JAMA. 2000; 283: 646–652.[Abstract/Free Full Text]

21. Vaccarino V, Parsons L, Every NR, et al. Sex-based differences in early mortality after myocardial infarction: National Registry of Myocardial Infarction 2 participants. N Engl J Med. 1999; 341: 217–225.[Abstract/Free Full Text]

22. Goldberg RJ, O‘Donnell C, Yarzebski J, et al. Sex differences in symptom presentation associated with acute myocardial infarction: a population-based perspective. Am Heart J. 1998; 136: 189–195.[Medline] [Order article via Infotrieve]

23. Burke AP, Farb A, Malcom GT, et al. Effect of risk factors on the mechanism of acute thrombosis and sudden coronary death in women. Circulation. 1998; 97: 2110–2116.[Abstract/Free Full Text]

24. Talbott E, Kuller LH, Perper J, et al. Sudden unexpected death in women: biologic and psychosocial origins. Am J Epidemiol. 1981; 114: 671–682.[Abstract/Free Full Text]

25. Beard CM, Griffin MR, Offord KP, et al. Risk factors for sudden unexpected cardiac death in young women in Rochester, Minnesota, 1960 through 1974. Mayo Clin Proc. 1986; 61: 186–191.[Medline] [Order article via Infotrieve]

26. Kannel WB, Wilson PW, D‘Agostino RB, et al. Sudden coronary death in women. Am Heart J. 1998; 136: 205–212.[Medline] [Order article via Infotrieve]

27. Lloyd-Jones DM, Martin DO, Larson MG, et al. Accuracy of death certificates for coding coronary heart disease as the cause of death. Ann Intern Med. 1998; 129: 1020–1026.[Abstract/Free Full Text]

28. Manolio TA, Furberg CD. Epidemiology of sudden cardiac death.In: Akhtar M, Myerburg RJ, Ruskin JN, eds. Sudden Cardiac Death: Prevalence, Mechanisms, and Approaches to Diagnosis and Management. Philadelphia, Pa: Williams and Wilkins; 1996: 3–20.

29. Folsom AR, Gomez-Marin O, Gillum RF, et al. Out-of-hospital coronary death in an urban population: validation of death certificate diagnosis. The Minnesota Heart Survey. Am J Epidemiol. 1987; 125: 1012–1018.[Abstract/Free Full Text]

30. Day JC. Population projections of the United States by age, sex, race, and Hispanic origin: 1995 to 2050. United States Bureau of the Census, Current Population Report Series P25-1130. Washington, DC: US Government Printing Office; 1996.

31. Rosenberg HM, Maurer JD, Sorlie PD, et al. Quality of death rates by race and Hispanic origin: a summary of current research, 1999. Vital Health Stat. 1999; 2: 1–13.

32. United States Department of Health and Human Services. Final report: methodology for adjusting IHS mortality data for inconsistent classification of race-ethnicity of American Indians and Alaska Natives between state death certificates and IHS patient registrations records. Washington, DC: United States Department of Health and Human Services; 1996.

33. Goff DC Jr, Sellers DE, McGovern PG, et al. Knowledge of heart attack symptoms in a population survey in the United States: the REACT Trial. Rapid Early Action for Coronary Treatment. Arch Intern Med. 1998; 158: 2329–2338.[Abstract/Free Full Text]

34. United States Department of Health and Human Services. Healthy People 2010, 2nd ed: With Understanding and Improving Health and Objectives for Improving Health. Washington, DC: US Government Printing Office; 2000.




This article has been cited by other articles:


Home page
EuropaceHome page
E. Z. Soliman, M. A. Elsalam, and Y. Li
The relationship between high resting heart rate and ventricular arrhythmogenesis in patients referred to ambulatory 24 h electrocardiographic recording
Europace, November 3, 2009; (2009) eup344v1.
[Abstract] [Full Text] [PDF]


Home page
Heart AsiaHome page
R J Sung and N-Y Chan
Practice viewpoints: AICD, who and when?
Heart Asia, October 15, 2009; 2009(10): 7 - 9.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
D. Yannopoulos, M. Zviman, V. Castro, A. Kolandaivelu, R. Ranjan, R. F. Wilson, and H. R. Halperin
Intra-Cardiopulmonary Resuscitation Hypothermia With and Without Volume Loading in an Ischemic Model of Cardiac Arrest
Circulation, October 6, 2009; 120(14): 1426 - 1435.
[Abstract] [Full Text] [PDF]


Home page
Br. J. Radiol.Home page
C R TAPPING and A D CULVERWELL
Are radiologists able to manage serious anaphylactic reactions and cardiopulmonary arrest?
Br. J. Radiol., October 1, 2009; 82(982): 793 - 799.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Heart Circ. Physiol.Home page
G. E. Billman
Cardiac autonomic neural remodeling and susceptibility to sudden cardiac death: effect of endurance exercise training
Am J Physiol Heart Circ Physiol, October 1, 2009; 297(4): H1171 - H1193.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
L. J. Shaw, J. K. Min, M. Budoff, H. Gransar, A. Rozanski, S. W. Hayes, J. D. Friedman, R. Miranda, N. D. Wong, and D. S. Berman
Induced cardiovascular procedural costs and resource consumption patterns after coronary artery calcium screening: results from the EISNER (Early Identification of Subclinical Atherosclerosis by Noninvasive Imaging Research) study.
J. Am. Coll. Cardiol., September 29, 2009; 54(14): 1258 - 1267.
[Abstract] [Full Text] [PDF]


Home page
AMERICAN JOURNAL OF LIFESTYLE MEDICINEHome page
A. S. Leon and U. G. Bronas
Pathophysiology of Coronary Heart Disease and Biological Mechanisms for the Cardioprotective Effects of Regular Aerobic Exercise
American Journal of Lifestyle Medicine, September 1, 2009; 3(5): 379 - 385.
[Abstract] [PDF]


Home page
Circ Cardiovasc Qual OutcomesHome page
R. M. Merchant, L. B. Becker, B. S. Abella, D. A. Asch, and P. W. Groeneveld
Cost-Effectiveness of Therapeutic Hypothermia After Cardiac Arrest
Circ Cardiovasc Qual Outcomes, September 1, 2009; 2(5): 421 - 428.
[Abstract] [Full Text] [PDF]


Home page
Circ Arrhythm ElectrophysiolHome page
E. L. Akylbekova, R. S. Crow, W. D. Johnson, S. G. Buxbaum, S. Njemanze, E. Fox, D. F. Sarpong, H. A. Taylor, and C. Newton-Cheh
Clinical Correlates and Heritability of QT Interval Duration in Blacks: The Jackson Heart Study
Circ Arrhythm Electrophysiol, August 1, 2009; 2(4): 427 - 432.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
S. Zaman, G. Sivagangabalan, A. Narayan, A. Thiagalingam, D. L. Ross, and P. Kovoor
Outcomes of Early Risk Stratification and Targeted Implantable Cardioverter-Defibrillator Implantation After ST-Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention
Circulation, July 21, 2009; 120(3): 194 - 200.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
J. P. Daubert
Why Are (Only) Some Infarcted Hearts Arrhythmogenic?
J. Am. Coll. Cardiol., July 7, 2009; 54(2): 174 - 175.
[Full Text] [PDF]


Home page
Eur Heart JHome page
J. Hollenberg, G. Riva, K. Bohm, P. Nordberg, R. Larsen, J. Herlitz, H. Pettersson, M. Rosenqvist, and L. Svensson
Dual dispatch early defibrillation in out-of-hospital cardiac arrest: the SALSA-pilot
Eur. Heart J., July 2, 2009; 30(14): 1781 - 1789.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
E. C. Korngold, J. L. Januzzi Jr, M. L. Gantzer, M.V. Moorthy, N. R. Cook, and C. M. Albert
Amino-Terminal Pro-B-Type Natriuretic Peptide and High-Sensitivity C-Reactive Protein as Predictors of Sudden Cardiac Death Among Women
Circulation, June 9, 2009; 119(22): 2868 - 2876.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
A. G. Garza, M. C. Gratton, J. A. Salomone, D. Lindholm, J. McElroy, and R. Archer
Improved Patient Survival Using a Modified Resuscitation Protocol for Out-of-Hospital Cardiac Arrest
Circulation, May 19, 2009; 119(19): 2597 - 2605.
[Abstract] [Full Text] [PDF]


Home page
J Intensive Care MedHome page
J. C. Reynolds, C. W. Callaway, S. R. El Khoudary, C. G. Moore, R. J. Alvarez, and J. C. Rittenberger
Review of A Large Clinical Series: Coronary Angiography Predicts Improved Outcome Following Cardiac Arrest: Propensity-adjusted Analysis
J Intensive Care Med, May 1, 2009; 24(3): 179 - 186.
[Abstract] [PDF]


Home page
QJMHome page
G. Boriani, M. Biffi, C. Martignani, I. Diemberger, C. Valzania, M. Bertini, and A. Branzi
Expenditure and value for money: the challenge of implantable cardioverter defibrillators
QJM, May 1, 2009; 102(5): 349 - 356.
[Abstract] [Full Text] [PDF]


Home page
RadioGraphicsHome page
P. J. Sparrow, N. Merchant, Y. L. Provost, D. J. Doyle, E. T. Nguyen, and N. S. Paul
CT and MR Imaging Findings in Patients with Acquired Heart Disease at Risk for Sudden Cardiac Death1
RadioGraphics, May 1, 2009; 29(3): 805 - 823.
[Abstract] [Full Text] [PDF]


Home page
Cardiovasc ResHome page
E. A. Woodcock, P. M. Kistler, and Y.-K. Ju
Phosphoinositide signalling and cardiac arrhythmias
Cardiovasc Res, May 1, 2009; 82(2): 286 - 295.
[Abstract] [Full Text] [PDF]


Home page
Ther Adv Cardiovasc DisHome page
R. Shephard and C. Semsarian
Advances in the prevention of sudden cardiac death in the young
Therapeutic Advances in Cardiovascular Disease, April 1, 2009; 3(2): 145 - 155.
[Abstract] [PDF]


Home page
J. Nutr.Home page
W. S. Harris, D. Mozaffarian, M. Lefevre, C. D. Toner, J. Colombo, S. C. Cunnane, J. M. Holden, D. M. Klurfeld, M. C. Morris, and J. Whelan
Towards Establishing Dietary Reference Intakes for Eicosapentaenoic and Docosahexaenoic Acids
J. Nutr., April 1, 2009; 139(4): 804S - 819S.
[Abstract] [Full Text] [PDF]


Home page
CMAJHome page
S. Setoguchi, A. Nohria, J. A. Rassen, L. W. Stevenson, and S. Schneeweiss
Maximum potential benefit of implantable defibrillators in preventing sudden death after hospital admission because of heart failure
Can. Med. Assoc. J., March 17, 2009; 180(6): 611 - 616.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
S. M. Narayan and M. B. Stein
Do depression or antidepressants increase cardiovascular mortality? The absence of proof might be more important than the proof of absence.
J. Am. Coll. Cardiol., March 17, 2009; 53(11): 959 - 961.
[Full Text] [PDF]


Home page
J Am Coll CardiolHome page
E. J. Rashba
Anger management may save your life new insights into emotional precipitants of ventricular arrhythmias.
J. Am. Coll. Cardiol., March 3, 2009; 53(9): 779 - 781.
[Full Text] [PDF]


Home page
Mayo Clin Proc.Home page
B. A. Koplan and W. G. Stevenson
Ventricular Tachycardia and Sudden Cardiac Death
Mayo Clin. Proc., March 1, 2009; 84(3): 289 - 297.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
W.H. L. Kao, D. E. Arking, W. Post, T. D. Rea, N. Sotoodehnia, R. J. Prineas, B. Bishe, B. Q. Doan, E. Boerwinkle, B. M. Psaty, et al.
Genetic Variations in Nitric Oxide Synthase 1 Adaptor Protein Are Associated With Sudden Cardiac Death in US White Community-Based Populations
Circulation, February 24, 2009; 119(7): 940 - 951.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
T. Iwami, G. Nichol, A. Hiraide, Y. Hayashi, T. Nishiuchi, K. Kajino, H. Morita, H. Yukioka, H. Ikeuchi, H. Sugimoto, et al.
Continuous Improvements in "Chain of Survival" Increased Survival After Out-of-Hospital Cardiac Arrests: A Large-Scale Population-Based Study
Circulation, February 10, 2009; 119(5): 728 - 734.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
G. A. Ewy and K. B. Kern
Recent advances in cardiopulmonary resuscitation: cardiocerebral resuscitation.
J. Am. Coll. Cardiol., January 13, 2009; 53(2): 149 - 157.
[Abstract] [Full Text] [PDF]


Home page
Circ Arrhythm ElectrophysiolHome page
Burst Stimulation Improves Hemodynamics During Resuscitation after Prolonged Ventricular Fibrillation.
Circ Arrhythm Electrophysiol, January 1, 2009; 2: 57 - 62.



Home page
CirculationHome page
B. J. Bobrow, M. Zuercher, G. A. Ewy, L. Clark, V. Chikani, D. Donahue, A. B. Sanders, R. W. Hilwig, R. A. Berg, and K. B. Kern
Gasping During Cardiac Arrest in Humans Is Frequent and Associated With Improved Survival
Circulation, December 9, 2008; 118(24): 2550 - 2554.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
R. W. Neumar, J. P. Nolan, C. Adrie, M. Aibiki, R. A. Berg, B. W. Bottiger, C. Callaway, R. S.B. Clark, R. G. Geocadin, E. C. Jauch, et al.
Post-Cardiac Arrest Syndrome: Epidemiology, Pathophysiology, Treatment, and Prognostication A Consensus Statement From the International Liaison Committee on Resuscitation (American Heart Association, Australian and New Zealand Council on Resuscitation, European Resuscitation Council, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Asia, and the Resuscitation Council of Southern Africa); the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; and the Stroke Council
Circulation, December 2, 2008; 118(23): 2452 - 2483.
[Full Text] [PDF]


Home page
Arterioscler. Thromb. Vasc. Bio.Home page
A. Breitenstein, S.F. Stampfli, G.G. Camici, A. Akhmedov, H.R. Ha, F. Follath, A. Bogdanova, T.F. Luscher, and F.C. Tanner
Amiodarone Inhibits Arterial Thrombus Formation and Tissue Factor Translation
Arterioscler Thromb Vasc Biol, December 1, 2008; 28(12): 2231 - 2238.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
P. A. Noseworthy and C. Newton-Cheh
Genetic Determinants of Sudden Cardiac Death
Circulation, October 28, 2008; 118(18): 1854 - 1863.
[Full Text] [PDF]


Home page
J Am Coll CardiolHome page
R. Rosso, E. Kogan, B. Belhassen, U. Rozovski, M. M. Scheinman, D. Zeltser, A. Halkin, A. Steinvil, K. Heller, M. Glikson, et al.
J-Point Elevation in Survivors of Primary Ventricular Fibrillation and Matched Control Subjects: Incidence and Clinical Significance
J. Am. Coll. Cardiol., October 7, 2008; 52(15): 1231 - 1238.
[Abstract] [Full Text] [PDF]


Home page
Circ Arrhythm ElectrophysiolHome page
J. K. Triedman
Should patients with congenital heart disease and a systemic ventricular ejection fraction less than 30% undergo prophylactic implantation of an ICD?: Implantable Cardioverter Defibrillator Implantation Guidelines Based Solely on Left Ventricular Ejection Fraction Do Not Apply to Adults With Congenital Heart Disease
Circ Arrhythm Electrophysiol, October 1, 2008; 1(4): 307 - 316.
[Full Text] [PDF]


Home page
PediatricsHome page
Council on School Health
Medical Emergencies Occurring at School
Pediatrics, October 1, 2008; 122(4): 887 - 894.
[Abstract] [Full Text] [PDF]


Home page
EuropaceHome page
L. Ding, W. Hua, H. Niu, K. Chen, and S. Zhang
Primary prevention of sudden cardiac death using implantable cardioverter defibrillators
Europace, September 1, 2008; 10(9): 1034 - 1041.
[Abstract] [Full Text] [PDF]


Home page
Nephrol Dial TransplantHome page
C. A. Herzog, J. W. Strief, A. J. Collins, and D. T. Gilbertson
Cause-specific mortality of dialysis patients after coronary revascularization: why don't dialysis patients have better survival after coronary intervention?
Nephrol. Dial. Transplant., August 1, 2008; 23(8): 2629 - 2633.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
J. Hollenberg, J. Herlitz, J. Lindqvist, G. Riva, K. Bohm, M. Rosenqvist, and L. Svensson
Improved Survival After Out-of-Hospital Cardiac Arrest Is Associated With an Increase in Proportion of Emergency Crew-Witnessed Cases and Bystander Cardiopulmonary Resuscitation
Circulation, July 22, 2008; 118(4): 389 - 396.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
W. S Harris
The omega-3 index as a risk factor for coronary heart disease
Am. J. Clinical Nutrition, June 1, 2008; 87(6): 1997S - 2002S.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
R. Byrne, O. Constant, Y. Smyth, G. Callagy, P. Nash, K. Daly, and J. Crowley
Multiple source surveillance incidence and aetiology of out-of-hospital sudden cardiac death in a rural population in the West of Ireland
Eur. Heart J., June 1, 2008; 29(11): 1418 - 1423.
[Abstract] [Full Text] [PDF]


Home page
HypertensionHome page
R. Deo, F. Lin, E. Vittinghoff, Z. H. Tseng, S. B. Hulley, and M. G. Shlipak
Kidney Dysfunction and Sudden Cardiac Death Among Women With Coronary Heart Disease
Hypertension, June 1, 2008; 51(6): 1578 - 1582.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
V. L. Vetter, J. Elia, C. Erickson, S. Berger, N. Blum, K. Uzark, and C. L. Webb
Cardiovascular Monitoring of Children and Adolescents With Heart Disease Receiving Medications for Attention Deficit/Hyperactivity Disorder: A Scientific Statement From the American Heart Association Council on Cardiovascular Disease in the Young Congenital Cardiac Defects Committee and the Council on Cardiovascular Nursing
Circulation, May 6, 2008; 117(18): 2407 - 2423.
[Full Text] [PDF]


Home page
Am J Crit CareHome page
D. L. Carroll and G. A. Hamilton
Long-term Effects of Implanted Cardioverter-Defibrillators on Health Status, Quality of Life, and Psychological State
Am. J. Crit. Care., May 1, 2008; 17(3): 222 - 230.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
G. Nichol, J. Rumsfeld, B. Eigel, B. S. Abella, D. Labarthe, Y. Hong, R. E. O'Connor, V. N. Mosesso, R. A. Berg, B. B. Leeper, et al.
Essential Features of Designating Out-of-Hospital Cardiac Arrest as a Reportable Event: A Scientific Statement From the American Heart Association Emergency Cardiovascular Care Committee; Council on Cardiopulmonary, Perioperative, and Critical Care; Council on Cardiovascular Nursing; Council on Clinical Cardiology; and Quality of Care and Outcomes Research Interdisciplinary Working Group
Circulation, April 29, 2008; 117(17): 2299 - 2308.
[Abstract] [Full Text] [PDF]


Home page
JAMAHome page
B. J. Bobrow, L. L. Clark, G. A. Ewy, V. Chikani, A. B. Sanders, R. A. Berg, P. B. Richman, and K. B. Kern
Minimally Interrupted Cardiac Resuscitation by Emergency Medical Services for Out-of-Hospital Cardiac Arrest
JAMA, March 12, 2008; 299(10): 1158 - 1165.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
M. de Lorgeril, P. Salen, T. Corcos, P. Defaye, M. Juneau, B. Pavy, and N. Saoudi
Is moderate drinking as effective as cholesterol lowering in reducing mortality in high-risk coronary patients?
Eur. Heart J., January 1, 2008; 29(1): 4 - 6.
[Full Text] [PDF]


Home page
CirculationHome page
C. M. Albert, E. G. Nam, E. B. Rimm, H. W. Jin, R. J. Hajjar, D. J. Hunter, C. A. MacRae, and P. T. Ellinor
Cardiac Sodium Channel Gene Variants and Sudden Cardiac Death in Women
Circulation, January 1, 2008; 117(1): 16 - 23.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
S. M. Narayan, M. R. Franz, G. Lalani, J. Kim, and A. Sastry
T-Wave Alternans, Restitution of Human Action Potential Duration, and Outcome
J. Am. Coll. Cardiol., December 18, 2007; 50(25): 2385 - 2392.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart J SupplHome page
G. Boriani, R. Ricci, T. Toselli, R. Ferrari, A. Branzi, and M. Santini
Implantable cardioverter defibrillators: from evidence of trials to clinical practice
Eur. Heart J. Suppl., December 1, 2007; 9(suppl_I): I66 - I73.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
H. Halperin, N. Paradis, V. Mosesso Jr, G. Nichol, M. Sayre, J. P. Ornato, M. Gerardi, V. M. Nadkarni, R. Berg, L. Becker, et al.
Recommendations for Implementation of Community Consultation and Public Disclosure Under the Food and Drug Administration's "Exception From Informed Consent Requirements for Emergency Research": A Special Report From the American Heart Association Emergency Cardiovascular Care Committee and Council on Cardiopulmonary, Perioperative and Critical Care: Endorsed by the American College of Emergency Physicians and the Society for Academic Emergency Medicine
Circulation, October 16, 2007; 116(16): 1855 - 1863.
[Full Text] [PDF]


Home page
JAMAHome page
L. H. Curtis, S. M. Al-Khatib, A. M. Shea, B. G. Hammill, A. F. Hernandez, and K. A. Schulman
Sex Differences in the Use of Implantable Cardioverter-Defibrillators for Primary and Secondary Prevention of Sudden Cardiac Death
JAMA, October 3, 2007; 298(13): 1517 - 1524.
[Abstract] [Full Text] [PDF]


Home page
JAMAHome page
A. F. Hernandez, G. C. Fonarow, L. Liang, S. M. Al-Khatib, L. H. Curtis, K. A. LaBresh, C. W. Yancy, N. M. Albert, and E. D. Peterson
Sex and Racial Differences in the Use of Implantable Cardioverter-Defibrillators Among Patients Hospitalized With Heart Failure
JAMA, October 3, 2007; 298(13): 1525 - 1532.
[Abstract] [Full Text] [PDF]


Home page
Postgrad. Med. J.Home page
W. H Ibrahim
Recent advances and controversies in adult cardiopulmonary resuscitation
Postgrad. Med. J., October 1, 2007; 83(984): 649 - 654.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
A. E. Buxton, K. L. Lee, G. E. Hafley, L. A. Pires, J. D. Fisher, M. R. Gold, M. E. Josephson, M. H. Lehmann, E. N. Prystowsky, and for the MUSTT Investigators
Limitations of Ejection Fraction for Prediction of Sudden Death Risk in Patients With Coronary Artery Disease: Lessons From the MUSTT Study
J. Am. Coll. Cardiol., September 18, 2007; 50(12): 1150 - 1157.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
H. K. Grogaard, L. Wik, M. Eriksen, M. Brekke, and K. Sunde
Continuous Mechanical Chest Compressions During Cardiac Arrest to Facilitate Restoration of Coronary Circulation With Percutaneous Coronary Intervention
J. Am. Coll. Cardiol., September 11, 2007; 50(11): 1093 - 1094.
[Full Text] [PDF]


Home page
Am J EpidemiolHome page
S Galea, S Blaney, A Nandi, R Silverman, D Vlahov, G Foltin, M Kusick, M Tunik, and N Richmond
Explaining Racial Disparities in Incidence of and Survival from Out-of-Hospital Cardiac Arrest
Am. J. Epidemiol., September 1, 2007; 166(5): 534 - 543.
[Abstract] [Full Text] [PDF]


Home page
ANN INTERN MEDHome page
B. Ali and A. M. Zafari
Narrative Review: Cardiopulmonary Resuscitation and Emergency Cardiovascular Care: Review of the Current Guidelines
Ann Intern Med, August 7, 2007; 147(3): 171 - 179.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
D. J. Cantillon, K. M. Stein, S. M. Markowitz, S. Mittal, B. K. Shah, D. P. Morin, E. S. Zacks, M. Janik, S. Ageno, A. C. Mauer, et al.
Predictive Value of Microvolt T-Wave Alternans in Patients With Left Ventricular Dysfunction
J. Am. Coll. Cardiol., July 10, 2007; 50(2): 166 - 173.
[Abstract] [Full Text] [PDF]


Home page
CMAJHome page
D. H. Birnie MB ChB MD, C. Sambell BSc, H. Johansen PhD, K. Williams MS, R. Lemery MD, M. S. Green MD, M. H. Gollob MD, D. S. Lee MD PhD, and A. S.L. Tang MD
Use of implantable cardioverter defibrillators in Canadian and US survivors of out-of-hospital cardiac arrest
Can. Med. Assoc. J., July 3, 2007; 177(1): 41 - 46.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Heart Circ. Physiol.Home page
D. L. Jardine, C. J. Charles, C. M. Frampton, and A. M. Richards
Cardiac sympathetic nerve activity and ventricular fibrillation during acute myocardial infarction in a conscious sheep model
Am J Physiol Heart Circ Physiol, July 1, 2007; 293(1): H433 - H439.
[Abstract] [Full Text] [PDF]


Home page
HeartHome page
H. T Carew, W. Zhang, and T. D Rea
Chronic health conditions and survival after out-of-hospital ventricular fibrillation cardiac arrest
Heart, June 1, 2007; 93(6): 728 - 731.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
W. G. Tingley, L. Pawlikowska, J. G. Zaroff, T. Kim, T. Nguyen, S. G. Young, K. Vranizan, P.-Y. Kwok, M. A. Whooley, and B. R. Conklin
Gene-trapped mouse embryonic stem cell-derived cardiac myocytes and human genetics implicate AKAP10 in heart rhythm regulation
PNAS, May 15, 2007; 104(20): 8461 - 8466.
[Abstract] [Full Text] [PDF]


Home page
JAMAHome page
P. J. Zimetbaum
A 59-Year-Old Man Considering Implantation of a Cardiac Defibrillator
JAMA, May 2, 2007; 297(17): 1909 - 1916.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
I. G. Stiell, R. G. Walker, L. P. Nesbitt, F. W. Chapman, D. Cousineau, J. Christenson, P. Bradford, S. Sookram, R. Berringer, P. Lank, et al.
BIPHASIC Trial: A Randomized Comparison of Fixed Lower Versus Escalating Higher Energy Levels for Defibrillation in Out-of-Hospital Cardiac Arrest
Circulation, March 27, 2007; 115(12): 1511 - 1517.
[Abstract] [Full Text] [PDF]


Home page
NEJMHome page
E. C. Keeley and L. D. Hillis
Primary PCI for Myocardial Infarction with ST-Segment Elevation
N. Engl. J. Med., January 4, 2007; 356(1): 47 - 54.
[Full Text] [PDF]


Home page
Health Aff (Millwood)Home page
M. L. Weisfeldt and S. J. Zieman
Advances In The Prevention And Treatment Of Cardiovascular Disease
Health Aff., January 1, 2007; 26(1): 25 - 37.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
T. D. Rea, M. Helbock, S. Perry, M. Garcia, D. Cloyd, L. Becker, and M. Eisenberg
Increasing Use of Cardiopulmonary Resuscitation During Out-of-Hospital Ventricular Fibrillation Arrest: Survival Implications of Guideline Changes
Circulation, December 19, 2006; 114(25): 2760 - 2765.
[Abstract] [Full Text] [PDF]


Home page
Arch Intern MedHome page
H. Losert, F. Sterz, K. Kohler, G. Sodeck, R. Fleischhackl, P. Eisenburger, A. Kliegel, H. Herkner, H. Myklebust, J. Nysaether, et al.
Quality of Cardiopulmonary Resuscitation Among Highly Trained Staff in an Emergency Department Setting
Arch Intern Med, November 27, 2006; 166(21): 2375 - 2380.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
Developed in Collaboration With the European Heart, D. P. Zipes, A. J. Camm, M. Borggrefe, A. E. Buxton, B. Chaitman, M. Fromer, G. Gregoratos, G. Klein, A. J. Moss, et al.
ACC/AHA/ESC 2006 Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death--Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death)
J. Am. Coll. Cardiol., September 5, 2006; 48(5): 1064 - 1108.
[Full Text] [PDF]


Home page
J Am Coll CardiolHome page
Developed in Collaboration With the European Heart, D. P. Zipes, A. J. Camm, M. Borggrefe, A. E. Buxton, B. Chaitman, M. Fromer, G. Gregoratos, G. Klein, A. J. Moss, et al.
ACC/AHA/ESC 2006 Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: A Report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death)
J. Am. Coll. Cardiol., September 5, 2006; 48(5): e247 - e346.
[Full Text] [PDF]


Home page
Eur Heart JHome page
D. P. Zipes, D. P. Zipes, A. J. Camm, M. Borggrefe, A. E. Buxton, B. Chaitman, M. Fromer, G. Gregoratos, G. Klein, A. J. Moss, et al.
ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death--executive summary: A report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death) Developed in collaboration with the European Heart Rhythm Association and the Heart Rhythm Society.
Eur. Heart J., September 1, 2006; 27(17): 2099 - 2140.
[Full Text] [PDF]


Home page
EuropaceHome page
Writing Committee Members, D. P. Zipes, A. J. Camm, M. Borggrefe, A. E. Buxton, B. Chaitman, M. Fromer, G. Gregoratos, G. Klein, A. J. Moss, et al.
ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: A report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death) Developed in collaboration with the European Heart Rhythm Association and the Heart Rhythm Society
Europace, September 1, 2006; 8(9): 746 - 837.
[Full Text] [PDF]


Home page
JAMAHome page
M. E. H. Ong, J. P. Ornato, D. P. Edwards, H. S. Dhindsa, A. M. Best, C. S. Ines, S. Hickey, B. Clark, D. C. Williams, R. G. Powell, et al.
Use of an automated, load-distributing band chest compression device for out-of-hospital cardiac arrest resuscitation.
JAMA, June 14, 2006; 295(22): 2629 - 2637.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
Y. Gerber, S. J. Jacobsen, R. L. Frye, S. A. Weston, J. M. Killian, and V. L. Roger
Secular Trends in Deaths From Cardiovascular Diseases: A 25-Year Community Study
Circulation, May 16, 2006; 113(19): 2285 - 2292.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
D. A. Cesario and G. W. Dec
Implantable Cardioverter- Defibrillator Therapy in Clinical Practice
J. Am. Coll. Cardiol., April 18, 2006; 47(8): 1507 - 1517.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
N. Sotoodehnia, D. S. Siscovick, M. Vatta, B. M. Psaty, R. P. Tracy, J. A. Towbin, R. N. Lemaitre, T. D. Rea, J. P. Durda, J. M. Chang, et al.
{beta}2-Adrenergic Receptor Genetic Variants and Risk of Sudden Cardiac Death
Circulation, April 18, 2006; 113(15): 1842 - 1848.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
T. Aufderheide, M. F. Hazinski, G. Nichol, S. S. Steffens, A. Buroker, R. McCune, E. Stapleton, V. Nadkarni, J. Potts, R. R. Ramirez, et al.
Community Lay Rescuer Automated External Defibrillation Programs: Key State Legislative Components and Implementation Strategies: A Summary of a Decade of Experience for Healthcare Providers, Policymakers, Legislators, Employers, and Community Leaders From the American Heart Association Emergency Cardiovascular Care Committee, Council on Clinical Cardiology, and Office of State Advocacy
Circulation, March 7, 2006; 113(9): 1260 - 1270.
[Abstract] [Full Text] [PDF]


Home page
Journal of Renin-Angiotensin-Aldosterone SystemHome page
K. Anand, A. N Mooss, and S. M Mohiuddin
Review: Aldosterone Inhibition Reduces the Risk of Sudden Cardiac Death in Patients with Heart Failure
Journal of Renin-Angiotensin-Aldosterone System, March 1, 2006; 7(1): 15 - 19.
[Abstract] [PDF]


Home page
Eur Heart JHome page
C. W. Israel and S. H. Hohnloser
Automated external defibrillation in emergency medical systems: what has been achieved and where to go?
Eur. Heart J., March 1, 2006; 27(5): 508 - 509.
[Full Text] [PDF]


Home page
CirculationHome page
T. Thom, N. Haase, W. Rosamond, V. J. Howard, J. Rumsfeld, T. Manolio, Z.-J. Zheng, K. Flegal, C. O'Donnell, S. Kittner, et al.
Heart Disease and Stroke Statistics--2006 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
Circulation, February 14, 2006; 113(6): e85 - e151.
[Full Text] [PDF]


Home page
J Am Coll CardiolHome page
S. M. Narayan
T-Wave Alternans and the Susceptibility to Ventricular Arrhythmias
J. Am. Coll. Cardiol., January 17, 2006; 47(2): 269 - 281.
[Abstract] [Full Text] [PDF]


This Article
Right arrow Abstract Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Zheng, Z.-J.
Right arrow Articles by Mensah, G. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Zheng, Z.-J.
Right arrow Articles by Mensah, G. A.
Right arrowPubmed/NCBI databases
Medline Plus Health Information
*Cardiac Arrest
Related Collections
Right arrow Restenosis
Right arrow Catheter-based coronary interventions: stents