Circulation. 2000;102:e17
(Circulation. 2000;102:e17.)
© 2000 American Heart Association, Inc.
Circulation Electronic Pages |
Risk of Cocaine-Induced Myocardial Infarction During Sport
Arthur J. Siegel, MD
Department of Internal Medicine McLean Hospital,
115 Mill Street,
Admissions Building,
Belmont, MA 02478-9106,
ajsiegel@mclean.harvard.edu
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Introduction
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To the Editor:
In the Determinants of Myocardial Infarction Onset Study, Mittleman et
al1 2 demonstrated triggering effects of myocardial
infarction in the hour immediately after cocaine use and strenuous
exercise, with 23.7- and 5.9-fold increases over baseline,
respectively.
Given the widespread use of cocaine among recreational and competitive
athletes, can an estimate be rendered from their data regarding the
cumulative risk of cocaine use during sport?
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References
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Mittleman MA, Mintzer D, Maclure M, et
al. Triggering of myocardial infarction by cocaine.
Circulation. 1999;99:27372741.[Abstract/Free Full Text]
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Mittleman MA, Maclure M, Tofler GH, et al, for the
Determinants of Myocardial Infarction Onset Study Investigators.
Triggering of acute myocardial infarction by heavy exertion: protection
against triggering by regular exertion. N Engl J
Med. 1993;329:16771683.[Abstract/Free Full Text]