Functional Integration of Electrically Active Cardiac Derivatives From Genetically Engineered Human Embryonic Stem Cells With Quiescent Recipient Ventricular Cardiomyocytes: Insights Into the Development of Cell-Based Pacemakers
Circulation Xue et al.
111: 11
Data Supplement
Files in this Data Supplement:
- Movie II
-
(AVI) (30.5). By varying the focus, Cx43 expression (red) could be observed throughout the 3-dimensional preparation of hESC-CM-NRVM coculture.
- Movie III
-
(MPG) (524 kb). Optical mapping of the left ventricle of a guinea pig heart pretransplanted with electrically active hESC-CMs before cryoablation.
- Movie IV
-
(MPG) (811 kb). Optical mapping of the left ventricle of a guinea pig heart pretransplanted with electrically active hESC-CMs after cryoablation.
- Movie I
-
(zipped AVI) (55 MB). Video of electrically active and spontaneously beating hESC-derived cardiomyocytes synchronously driving otherwise quiescent and noncontracting neonatal rat ventricular cardiomyocytes in an in vitro transplantation model.