Files in this Data Supplement:

• Table 1 - (MS Word) (24 kb). Patient Data. Clinical data of patients who had both a measurement of arterial stiffness and a punch biopsy of the ascending aorta is presented. Patients were classified according to tertiles of adjusted PWV.
• Table 2 - (MS Excel) (26 kb). Differential expression of genes involved in arterial mechanics. Filtering was performed as indicated in Figure 1A. The top section of the table includes genes chosen based on correlation coefficient, the mid region of the table included genes exhibiting an all-or-none pattern of expression (comparing distensible to stiff), and the bottom section includes genes with a P>0.05. The Description, Locus Name, Map Position and GO Annotations are from the Affymetrix web site (http://www.affymetrix.com). Gene Descriptions in boldfaced type indicate genes present in more than one group.
• Table 3 - (MS Excel) (51 kb). Differential expression of genes. Filtering was performed as indicated in Figure 1B. The top section of the table includes genes chosen based on correlation coefficient, the mid region of the table included genes exhibiting an all-or-none pattern of expression (comparing distensible to stiff), and the bottom section includes genes with a P>0.05. The Description, Locus Name, Map Position and GO Annotations are from the Affymetrix web site (http://www.affymetrix.com). Gene Descriptions in boldfaced type indicate genes present in more than one group.