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(Circulation. 2006;113:177.)
© 2006 American Heart Association, Inc.

Issue Highlights

An extract of the first 250 words of the full text is provided, because this article has no abstract.

	LONG-TERM ADHERENCE TO EVIDENCE-BASED SECONDARY PREVENTION THERAPIES IN CORONARY ARTERY DISEASE, by Newby et al.

 
Many studies have focused on the underuse of various secondary prevention treatments at hospital discharge and, as a result, performance is improving. However, our knowledge about the long-term use of these interventions is much more limited because of substantial challenges in the collection of outpatient data. To address this issue, Duke investigators have made use of the Duke Databank for Cardiovascular Disease, which has been augmented with follow-up information that includes self-reported medications. The study includes 31 750 patients with coronary artery disease confirmed by catheterization who were seen at Duke from 1995 through 2002. The findings reveal some remarkable insights about the consistent use rates of important secondary prevention therapies. See p 203.

	MYOCARDIAL VIABILITY TESTING AND THE EFFECT OF EARLY INTERVENTION IN PATIENTS WITH ADVANCED LEFT VENTRICULAR SYSTOLIC DYSFUNCTION, by Tarakji et al.

 
Controversy remains regarding the role of revascularization in patients with heart failure and left ventricular dysfunction. Observational studies suggest that such patients with preserved viability and ischemia benefit from revascularization, but definitive recommendations are constrained by limitations and biases inherent in cohort analyses. In this issue of Circulation, Tarakji and colleagues report on patients referred for positron-emission tomography imaging of viability during consideration of revascularization. Propensity scoring was used to match patients who underwent revascularization to a group that was treated medically. Revascularization was associated with a 48% reduction in the risk of mortality over 3 years. Of interest, the modeled outcomes suggested only minor influence of the extent of viability on the effect of revascularization. Short of a full randomized trial, these data provide the most robust analysis to date of the potential . . . [Full Text of this Article]

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