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(Circulation. 2006;113:2031.)
© 2006 American Heart Association, Inc.

Issue Highlights

An extract of the first 250 words of the full text is provided, because this article has no abstract.

	PHYSIOLOGICAL AND CLINICAL CONSEQUENCES OF RELIEF OF RIGHT VENTRICULAR OUTFLOW TRACT OBSTRUCTION LATE AFTER REPAIR OF CONGENITAL HEART DEFECTS, by Coats et al.

 
Right ventricular outflow tract obstruction is a common problem in patients with repaired congenital heart disease. Percutaneous pulmonary valve implantation (PPVI) can treat this condition without consequent pulmonary regurgitation or cardiopulmonary bypass. Coats and colleagues studied the clinical and physiological response to relieving right ventricular outflow tract obstruction, without pulmonary regurgitation, with use of PPVI in 18 patients with complex congenital heart defects. They found improvement in symptoms, exercise tolerance, and ventricular function. The use of PPVI permits, for the first time, investigation of the early direct effects of relief of chronic right ventricular pressure overload on cardiac function. Longer-term follow-up is needed before PPVI can be recommended as a treatment for right ventricular outflow tract obstruction. See p 2037.

	COFFEE CONSUMPTION AND CORONARY HEART DISEASE IN MEN AND WOMEN: A PROSPECTIVE COHORT STUDY, by Lopez-Garcia et al.

 
The relation of coffee consumption to cardiovascular disease has been the focus of intensive study, due in part to the ubiquitous nature of coffee consumption and shops in Europe and North America. In the present issue of Circulation, Lopez-Garcia and colleagues provide analyses of 2 large epidemiological data sets, the Health Professionals Follow-up Study of 44 005 men and the Nurse’s Health Study of 84 488 women, to shed further light on the topic. With caffeine consumption habits updated periodically, the ability to account for important confounders such as smoking, 1 to 2 decades of follow-up, and over 4000 cases of incident coronary heart disease, the investigators found that caffeine was not associated with increased risk of coronary heart disease. Similarly, they found no association between decaffeinated coffee . . . [Full Text of this Article]

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