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Circulation. 2009;120:1847-1849
Published online before print October 26, 2009, doi: 10.1161/CIRCULATIONAHA.109.904458
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(Circulation. 2009;120:1847-1849.)
© 2009 American Heart Association, Inc.


Editorial

Radiation Risk From Pediatric Cardiac Catheterization

Friendly Fire on Children With Congenital Heart Disease

Maria Grazia Andreassi, BSc, PhD

From the CNR Institute of Clinical Physiology, Pisa, Italy, and G. Monasterio Foundation, Massa, Italy.

Correspondence to Dr Maria Grazia Andreassi, CNR Institute of Clinical Physiology, G. Monasterio Foundation, Via Aurelia Sud-Montepepe, 54100 Massa, Italy. E-mail andreas@ifc.cnr.it


Key Words: Editorials • heart defects, congenital • radiation • pediatrics


An extract of the first 250 words of the full text is provided, because this article has no abstract.
 


*    Introduction
 
Congenital heart disease (CHD) is the most prevalent and fatal of all birth defects, occurring in nearly 1 in 100 live births.1 Before the advent of cardiac surgery for congenital cardiac malformations, less than one fifth of children born with such lesions reached adulthood. The progress of surgical management and, more recently, interventional catheterization has allowed an increasing number of congenital heart defects to be corrected surgically so that an increasing number of patients reach adolescence and adult life, even those with complex defects.2,3

Article see p 1903

Indeed, grown-up patients with surgically repaired CHD are a large and growing population, estimated to be 1 million in United States in the year 2000 compared with an estimated 300 000 in 1980, and 1.4 million cases are anticipated in 2020.2 Numbers are likely to be similar in the European Union, although no hard figures are available.3

One worrisome social and medical problem in the management of patients with CHD is certainly the long-term effects of intensive medical exposure to ionizing radiation received during childhood, especially for interventional catheterization procedures.4–7 Pediatric cardiac catheterizations are undoubtedly an essential diagnostic and therapeutic tool for the diagnosis and the treatment of CHD; however, they also deliver one of the highest radiation doses to patients.4–7

Ionizing radiation exposure is a definite risk factor for cancer development. Children are especially vulnerable to the oncogenic effects of radiation. Tissues and organs that are growing and developing are more sensitive to radiation effects than those that are fully mature. . . . [Full Text of this Article]