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(Circulation. 2009;120:1843-1844.)
© 2009 American Heart Association, Inc.

Clinical Summaries

An extract of the first 250 words of the full text is provided, because this article has no abstract.

	Anthropometry, Body Fat, and Venous Thromboembolism: A Danish Follow-Up Study

 
The distribution of body fat predicts the risk of coronary heart disease, and central obesity consistently has been shown to be a risk factor for coronary heart disease, whereas peripheral obesity (measured as high hip circumference) appears to protect against coronary heart disease. The importance of fat distribution with regard to the risk of venous thromboembolism (VTE), ie, deep venous thrombosis and pulmonary embolism, has not been evaluated. In a 10-year follow-up study of 56 014 middle-aged men and women, which included 641 verified incident events of VTE, we evaluated the risk of VTE according to different measurements of fat distribution in the body. Our results show that all measurements of obesity are positively associated with VTE in both sexes. We also showed that a higher hip circumference in normal-weight persons was associated with a higher risk for VTE, which is in contrast to studies on coronary heart disease. We found statistically significant positive associations between idiopathic (unprovoked) VTE and all measurements of obesity. The associations between VTE and the anthropometric measurements persisted after adjustment for hypertension, diabetes mellitus, or hypercholesterolemia, which shows that the effect of obesity was not mediated solely by these factors. See p 1850.

	Cardiac Resynchronization Induces Major Structural and Functional Reverse Remodeling in Patients With New York Heart Association Class I/II Heart Failure

 
Cardiac resynchronization therapy (CRT) has proved efficacious in New York Heart Association (NYHA) class III/IV heart failure (HF). This key echocardiographic study assessed the impact of CRT on structural and functional reverse remodeling in patients with NYHA class I/II HF. The REsynchronization reVErses Remodeling in Systolic left vEntricular dysfunction (REVERSE) trial . . . [Full Text of this Article]

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