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(Circulation. 2007;116:1997.)
© 2007 American Heart Association, Inc.

Issue Highlights

An extract of the first 250 words of the full text is provided, because this article has no abstract.

	PREDICTION OF ATRIAL FIBRILLATION VIA ATRIAL ELECTROMECHANICAL INTERVAL AFTER CORONARY ARTERY BYPASS GRAFTING, by Roshanali et al

 
Atrial fibrillation (AF) is a common complication of cardiac surgery that is associated with increased morbidity, length of hospitalization, and costs. Yet, the risks and inconvenience of prophylactic therapies is such that many are not routinely used. Roshanali and coworkers prospectively evaluated the delay between the onset of the P wave and echocardiographically detected lateral left atrial contraction (atrial electromechanical interval), as a predictor of AF after coronary artery bypass surgery in 365 patients with no prior history of AF. AF occurred in 19.2% of patients and was associated with increased length of hospitalization. A long atrial electromechanical interval was an excellent predictor of postoperative AF. The atrial electromechanical interval is a simple convenient marker that could potentially be used in future studies to target strategies for preventing postoperative AF in high-risk patients. See p 2012.

	APOLIPOPROTEIN A-II IS INVERSELY ASSOCIATED WITH RISK OF FUTURE CORONARY ARTERY DISEASE, by Birjmohun et al

 
Controversy exists on whether apolipoprotein A-II (apoA-II), the primary high-density lipoprotein–associated protein, lowers risk, is neutral, or is proatherosclerotic. In one of the largest studies to date, Birjmohun and colleagues conducted a nested case control study of whether apoA-I and apoA-II predict incident coronary artery disease in the EPIC-Norfolk (European Prospective Investigation into Cancer and Nutrition--Norfolk) cohort. Middle-aged to elderly men and women were matched on age, sex, and enrollment time and followed up for an average of 6 years. The investigators observed that apoA-II concentrations were protective for risk of future coronary artery disease. Individuals in the highest quartile had about half the adjusted odds of incident coronary disease compared with those . . . [Full Text of this Article]

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