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(Circulation. 2007;115:1177.)
© 2007 American Heart Association, Inc.

Issue Highlights

An extract of the first 250 words of the full text is provided, because this article has no abstract.

	REMOTE MAGNETIC NAVIGATION TO GUIDE ENDOCARDIAL AND EPICARDIAL CATHETER MAPPING OF SCAR-RELATED VENTRICULAR TACHYCARDIA, by Aryana et al.

 
Catheter mapping of ventricular tachycardia is challenging because of tissue heterogeneity in diverse scar-related disease substrates as well as limitations in maneuverability and accessibility to critical regions of the ventricular endocardium and epicardium. In this issue of Circulation, Aryana and colleagues report their clinical results obtained by using a remote magnetic navigation system combined with electroanatomic mapping to identify areas of interest related to ventricular tachycardia, while using a limited amount of fluoroscopy exposure. Although the majority of epicardial and endocardial ventricular sites could be safely and effectively mapped remotely, because of current limitations of the magnetic navigation catheter, most patients required additional manual ablation using an irrigated catheter to ablate fully the ventricular tachycardia substrates. See p 1191.

	RENAL INSUFFICIENCY FOLLOWING CONTRAST MEDIA ADMINISTRATION TRIAL (REMEDIAL): A RANDOMIZED COMPARISON OF 3 PREVENTIVE STRATEGIES, by Briguori et al.

 
Exposure to radiocontrast media can lead to transient and permanent renal failure in high-risk patients such as those with preexisting moderate or severe renal failure. Current methods to prevent contrast-induced nephrotoxicity include volume expansion with saline and limitation of contrast volume. Other strategies have been proposed, including N-acetylcysteine (NAC), sodium bicarbonate infusion, and ascorbic acid. The study by Briguori et al was a 2-center, randomized, double-blind study of 3 strategies to prevent contrast-induced nephrotoxicity in 326 patients with moderate chronic renal disease undergoing coronary or peripheral angiography. Moderate renal failure was defined as a creatinine concentration of 2 to 8 mg/dL. Patients were randomized to saline plus NAC, sodium bicarbonate infusion plus NAC, or saline plus ascorbic acid plus NAC. Contrast-induced nephropathy defined as an increase in creatinine concentration . . . [Full Text of this Article]

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