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(Circulation. 2006;113:e924-e929.)
© 2006 American Heart Association, Inc.

Clinician Update

South Asians and Cardiovascular Risk

What Clinicians Should Know

Milan Gupta, MD; Narendra Singh, MD; Subodh Verma, MD, PhD

From the Division of Cardiology, William Osler Health Centre (M.G.), McMaster University, Hamilton, Canada; Division of Cardiology, Northside Hospital (N.S.), Emory University, Atlanta, Ga; and Division of Cardiac Surgery, St. Michael’s Hospital (S.V.), University of Toronto, Toronto, Canada.

Correspondence to Milan Gupta, MD, 164 Queen St E, Suite 211, Brampton, ON L6V1B4 Canada. E-mail mkgupta@rogers.com

An extract of the first 250 words of the full text is provided, because this article has no abstract.

	Introduction

 
Case presentation: A 36-year-old nonsmoking, normotensive South Asian man presented to the emergency department of a community hospital with retrosternal chest pain of &60 minutes’ duration. His 12-lead ECG demonstrated 10 mm of ST-segment elevation in leads V₂ through V₆, and he received fibrinolytic therapy within 90 minutes of symptom onset. His pain resolved, but his ST segments only partially normalized; he had a peak creatine kinase of 4564 IU/L, and he showed signs of early heart failure. LDL cholesterol was 135 mg/dL, HDL 32 mg/dL, triglycerides 20 mg/dL, and total cholesterol 206 mg/dL; his body mass index (BMI) was 24 kg/m². Cardiac catheterization demonstrated severe and diffuse triple-vessel disease, including occlusion of the proximal left anterior descending artery, as well as moderate left ventricular dysfunction. While in the hospital, he was diagnosed with new-onset type 2 diabetes mellitus and subsequently underwent uncomplicated coronary bypass surgery.

	South Asians and Cardiovascular Disease

 
South Asians are individuals whose ethnic roots originate from the Indian subcontinent, a large geographic area that includes India, Pakistan, Sri Lanka, Nepal, and Bangladesh. Collectively, South Asians represent one fifth of the global population. In North America, more than 2 million South Asians reside in the United States and almost 1 million in Canada. It is important to recognize that the term "South Asian" refers to a heterogeneous population, with important differences in diet, culture, and lifestyle among different South Asian populations and religions. Multiple studies of migrant South Asian populations have, however, confirmed a 3- to 5-fold increase in the . . . [Full Text of this Article]

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