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(Circulation. 2006;113:2783.)
© 2006 American Heart Association, Inc.

Issue Highlights

An extract of the first 250 words of the full text is provided, because this article has no abstract.

	COGNITIVE OUTCOMES IN ELDERLY HIGH-RISK PATIENTS AFTER OFF-PUMP VERSUS CONVENTIONAL CORONARY ARTERY BYPASS GRAFTING: A RANDOMIZED TRIAL, by Jensen et al.

 
Understanding neurocognitive outcomes after coronary bypass surgery has been the focus of many recent investigations, few of which were randomized studies. The incidence of stroke is a perioperative event, but postoperative cognitive dysfunction is a condition characterized by impairment of memory or concentration. The article "Cognitive Outcomes in Elderly High-Risk Patients After Off-Pump Versus Conventional Coronary Artery Bypass Grafting: A Randomized Trial," by Jensen et al, addresses these issues in a substudy of the randomized Best Bypass Surgery (BBS) Trial that compared off-pump coronary artery bypass grafting to conventional coronary artery bypass grafting treatment, with respect to preoperative and postoperative morbidity in patients with a moderate to high predicted preoperative risk. The outcome was cognitive function in 120 elderly patients (mean age 76 years) who underwent psychometric testing before surgery and at a mean of 103 (standard deviation, 15) days postoperatively, using a neuropsychological test battery with 7 parameters from 4 tests. Cognitive dysfunction was defined as the occurrence of at least 2 deficits out of a possible 7. The authors found no difference in the incidence of cognitive dysfunction between the groups regardless of the definition applied. The search for techniques and strategies to enhance the safety of coronary surgery will continue. See p 2790.

	CAUSES AND CONSEQUENCES OF HEART FAILURE AFTER PROPHYLACTIC IMPLANTATION OF A DEFIBRILLATOR IN THE MULTICENTER AUTOMATIC DEFIBRILLATOR IMPLANTATION TRIAL II, by Goldenberg et al.

 
Depressed left ventricular function is a marker for both arrhythmias and heart failure. Implantable cardioverter defibrillators (ICDs) reduce sudden arrhythmic death and prolong survival in selected patient populations. Goldenberg and colleagues examined the relationship between ICD therapy, survival and heart failure hospitalizations in . . . [Full Text of this Article]

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