From the Framingham Heart Study, National Heart, Lung, and Blood
Institute, Framingham, Mass (P.W.F.W., D.L.); Boston University Mathematics
Department, Boston, Mass (R.B.D., A.M.B., H.S.); and Framingham Heart Study,
Boston University School of Medicine, Framingham, Mass (W.B.K.).
Background—The objective of this
study was to examine the association of Joint National Committee
(JNC-V) blood pressure and National Cholesterol Education
Program (NCEP) cholesterol categories with coronary
heart disease (CHD) risk, to incorporate them into coronary
prediction algorithms, and to compare the discrimination properties of
this approach with other noncategorical prediction functions.
Methods and Results—This work was designed as a prospective,
single-center study in the setting of a community-based cohort. The
patients were 2489 men and 2856 women 30 to 74 years old at baseline
with 12 years of follow-up. During the 12 years of follow-up, a total
of 383 men and 227 women developed CHD, which was significantly
associated with categories of blood pressure, total
cholesterol, LDL cholesterol, and HDL
cholesterol (all P<.001). Sex-specific
prediction equations were formulated to predict CHD risk according to
age, diabetes, smoking, JNC-V blood pressure categories, and NCEP total
cholesterol and LDL cholesterol categories. The
accuracy of this categorical approach was found to be comparable to CHD
prediction when the continuous variables themselves were used.
After adjustment for other factors,
Conclusions—Recommended guidelines of blood pressure, total
cholesterol, and LDL cholesterol effectively
predict CHD risk in a middle-aged white population sample. A simple
coronary disease prediction algorithm was developed using
categorical variables, which allows physicians to predict
multivariate CHD risk in patients without overt CHD.
© 1998 American Heart Association, Inc.
Special Reports
Prediction of Coronary Heart Disease Using Risk Factor Categories
28% of CHD events in men and
29% in women were attributable to blood pressure levels that exceeded
high normal (
130/85). The corresponding multivariable-adjusted
attributable risk percent associated with elevated total
cholesterol (200 mg/dL) was 27% in men and 34% in
women.
Key Words: coronary disease • prediction • hypertension • cholesterol
This article has been cited by other articles:
 |
|
 |
|
  G. Silbernagel, G. Fauler, M. M. Hoffmann, D. Lutjohann, B. R. Winkelmann, B. O. Boehm, and W. Marz The associations of cholesterol metabolism and plasma plant sterols with all-cause and cardiovascular mortality J. Lipid Res., August 1, 2010; 51(8): 2384 - 2393. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Murray, S. Saxena, C. Millett, V. Curcin, S. de Lusignan, and A. Majeed Reductions in risk factors for secondary prevention of coronary heart disease by ethnic group in south-west London: 10-year longitudinal study (1998-2007) Fam. Pract., August 1, 2010; 27(4): 430 - 438. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. G. Schneider, Z. Yang, M. V. Chakravarthy, I. J. Lodhi, X. Wei, J. Turk, and C. F. Semenkovich Macrophage Fatty-acid Synthase Deficiency Decreases Diet-induced Atherosclerosis J. Biol. Chem., July 23, 2010; 285(30): 23398 - 23409. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. G. Le Couteur and E. G. Lakatta A Vascular Theory of Aging J Gerontol A Biol Sci Med Sci, July 22, 2010; (2010) glq135v1. [Full Text] [PDF]
|
|
|
|
 |
|
 M. T. Cooney, A. Dudina, R. D'Agostino, and I. M. Graham Cardiovascular Risk-Estimation Systems in Primary Prevention: Do They Differ? Do They Make a Difference? Can We See the Future? Circulation, July 20, 2010; 122(3): 300 - 310. [Full Text] [PDF]
|
|
|
|
|
|
M. Gulati, L. J. Shaw, R. A. Thisted, H. R. Black, C. N. Bairey Merz, and M. F. Arnsdorf Heart Rate Response to Exercise Stress Testing in Asymptomatic Women: The St. James Women Take Heart Project Circulation, July 13, 2010; 122(2): 130 - 137. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. Seyahi, A. Kahveci, D. Cebi, M. R. Altiparmak, C. Akman, I. Uslu, R. Ataman, H. Tasci, and K. Serdengecti Coronary artery calcification and coronary ischaemia in renal transplant recipients Nephrol. Dial. Transplant., July 9, 2010; (2010) gfq413v1. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. A. Szczech, D. B. Bregman, R. A. Harrington, D. Morris, A. Butcher, T. A. Koch, L. T. Goodnough, M. Wolf, and J. E. Onken Randomized Evaluation of efficacy and safety of ferric carboxymaltose in Patients with iron deficiency Anaemia and Impaired Renal function (REPAIR-IDA): rationale and study design Nephrol. Dial. Transplant., July 1, 2010; 25(7): 2368 - 2375. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Sala-Vila, M. Cofan, A. Perez-Heras, I. Nunez, R. Gilabert, M. Junyent, R. Mateo-Gallego, A. Cenarro, F. Civeira, and E. Ros Fatty acids in serum phospholipids and carotid intima-media thickness in Spanish subjects with primary dyslipidemia Am. J. Clinical Nutrition, July 1, 2010; 92(1): 186 - 193. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Kalogeropoulos, B. M. Psaty, R. S. Vasan, V. Georgiopoulou, A. L. Smith, N. L. Smith, S. B. Kritchevsky, P. W. F. Wilson, A. B. Newman, T. B. Harris, et al. Validation of the Health ABC Heart Failure Model for Incident Heart Failure Risk Prediction: The Cardiovascular Health Study Circ Heart Fail, July 1, 2010; 3(4): 495 - 502. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. L. Sheridan, J. M. Griffith, L. Behrend, Z. Gizlice, Jianwen Cai, and M. P. Pignone Effect of Adding a Values Clarification Exercise to a Decision Aid on Heart Disease Prevention: A Randomized Trial Med Decis Making, July 1, 2010; 30(4): E28 - E39. [Abstract] [PDF]
|
|
|
|
 |
|
 L. Bunting and J. Boivin Development and preliminary validation of the fertility status awareness tool: FertiSTAT Hum. Reprod., July 1, 2010; 25(7): 1722 - 1733. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Dai, R. Lampert, P. W. Wilson, J. Goldberg, T. R. Ziegler, and V. Vaccarino Mediterranean Dietary Pattern Is Associated With Improved Cardiac Autonomic Function Among Middle-Aged Men: A Twin Study Circ Cardiovasc Qual Outcomes, July 1, 2010; 3(4): 366 - 373. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. M. Perrin and W. Serino Ischaemic heart disease - a new issue in cystic fibrosis? J R Soc Med, July 1, 2010; 103(Supplement_1): S44 - S48. [Full Text] [PDF]
|
|
|
|
 |
|
 L. B. Travis, C. Beard, J. M. Allan, A. A. Dahl, D. R. Feldman, J. Oldenburg, G. Daugaard, J. L. Kelly, M. E. Dolan, R. Hannigan, et al. Testicular Cancer Survivorship: Research Strategies and Recommendations J Natl Cancer Inst, June 28, 2010; (2010) djq216v1. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. B. Mark, D. S. Berman, M. J. Budoff, J. J. Carr, T. C. Gerber, H. S. Hecht, M. A. Hlatky, J. M. Hodgson, M. S. Lauer, J. M. Miller, et al. ACCF/ACR/AHA/NASCI/SAIP/SCAI/SCCT 2010 Expert Consensus Document on Coronary Computed Tomographic Angiography: A Report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents J. Am. Coll. Cardiol., June 8, 2010; 55(23): 2663 - 2699. [Full Text] [PDF]
|
|
|
|
|
|
WRITING COMMITTEE MEMBERS, D. B. Mark, D. S. Berman, M. J. Budoff, J. J. Carr, T. C. Gerber, H. S. Hecht, M. A. Hlatky, J. M. Hodgson, M. S. Lauer, et al. ACCF/ACR/AHA/NASCI/SAIP/SCAI/SCCT 2010 Expert Consensus Document on Coronary Computed Tomographic Angiography: A Report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents Circulation, June 8, 2010; 121(22): 2509 - 2543. [Full Text] [PDF]
|
|
|
|
 |
|
 M. Kozakova, C. Palombo, C. Morizzo, J. J. Nolan, T. Konrad, B. Balkau, and the RISC Investigators Effect of sedentary behaviour and vigorous physical activity on segment-specific carotid wall thickness and its progression in a healthy population Eur. Heart J., June 2, 2010; 31(12): 1511 - 1519. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Thanassoulis, J. M. Massaro, R. Cury, E. Manders, E. J. Benjamin, R. S. Vasan, L. A. Cupple, U. Hoffmann, C. J. O'Donnell, and S. Kathiresan Associations of Long-Term and Early Adult Atherosclerosis Risk Factors With Aortic and Mitral Valve Calcium. J. Am. Coll. Cardiol., June 1, 2010; 55(22): 2491 - 2498. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Gupta, J. D. Berry, C. R. Ayers, R. M. Peshock, A. Khera, J. A. de Lemos, P. C. Patel, D. W. Markham, and M. H. Drazner Left Ventricular Hypertrophy, Aortic Wall Thickness, and Lifetime Predicted Risk of Cardiovascular Disease: The Dallas Heart Study J. Am. Coll. Cardiol. Img., June 1, 2010; 3(6): 605 - 613. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. H. Schindler, H. R. Schelbert, A. Quercioli, and V. Dilsizian Cardiac PET Imaging for the Detection and Monitoring of Coronary Artery Disease and Microvascular Health J. Am. Coll. Cardiol. Img., June 1, 2010; 3(6): 623 - 640. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Kitamura, T. Iwami, G. Nichol, T. Nishiuchi, Y. Hayashi, C. Nishiyama, T. Sakai, K. Kajino, A. Hiraide, H. Ikeuchi, et al. Reduction in incidence and fatality of out-of-hospital cardiac arrest in females of the reproductive age Eur. Heart J., June 1, 2010; 31(11): 1365 - 1372. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Hadamitzky, F. Hein, T. Meyer, B. Bischoff, S. Martinoff, A. Schomig, and J. Hausleiter Prognostic Value of Coronary Computed Tomographic Angiography in Diabetic Patients Without Known Coronary Artery Disease Diabetes Care, June 1, 2010; 33(6): 1358 - 1363. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Ai, S. Otokozawa, B. F. Asztalos, Y. Ito, K. Nakajima, C. C. White, L. A. Cupples, P. W. Wilson, and E. J. Schaefer Small Dense LDL Cholesterol and Coronary Heart Disease: Results from the Framingham Offspring Study Clin. Chem., June 1, 2010; 56(6): 967 - 976. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. J. Mukamal A 42-Year-Old Man Considering Whether to Drink Alcohol for His Health JAMA, May 26, 2010; 303(20): 2065 - 2073. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. E. Humphries, F. Drenos, G. Ken-Dror, and P. J. Talmud Coronary Heart Disease Risk Prediction in the Era of Genome-Wide Association Studies: Current Status and What the Future Holds Circulation, May 25, 2010; 121(20): 2235 - 2248. [Full Text] [PDF]
|
|
|
|
|
|
H. C. Kim, P. Greenland, J. E. Rossouw, J. E. Manson, B. B. Cochrane, N. L. Lasser, M. C. Limacher, D. M. Lloyd-Jones, K. L. Margolis, and J. G. Robinson Multimarker Prediction of Coronary Heart Disease Risk: The Women's Health Initiative J. Am. Coll. Cardiol., May 11, 2010; 55(19): 2080 - 2091. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. I. Yang, M. Sherman, J. Su, P. J. Chen, Y. F. Liaw, U. H. Iloeje, and C. J. Chen Nomograms for Risk of Hepatocellular Carcinoma in Patients With Chronic Hepatitis B Virus Infection J. Clin. Oncol., May 10, 2010; 28(14): 2437 - 2444. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. H. Solomon, J. Kremer, J. R. Curtis, M. C. Hochberg, G. Reed, P. Tsao, M. E. Farkouh, S. Setoguchi, and J. D. Greenberg Explaining the cardiovascular risk associated with rheumatoid arthritis: traditional risk factors versus markers of rheumatoid arthritis severity Ann Rheum Dis, May 5, 2010; (2010) ard.2009.122226v1. [Abstract] [Full Text]
|
|
|
|
|
|
E. Polisecki, I. Peter, J. S. Simon, R. A. Hegele, M. Robertson, I. Ford, J. Shepherd, C. Packard, J. W. Jukema, A. J. M. de Craen, et al. Genetic variation at the NPC1L1 gene locus, plasma lipoproteins, and heart disease risk in the elderly J. Lipid Res., May 1, 2010; 51(5): 1201 - 1207. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. W. Davidson, E. Mostofsky, and W. Whang Don't worry, be happy: positive affect and reduced 10-year incident coronary heart disease: The Canadian Nova Scotia Health Survey Eur. Heart J., May 1, 2010; 31(9): 1065 - 1070. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. EL-GABALAWY, L. C. GUENTHER, and C. N. BERNSTEIN Epidemiology of Immune-Mediated Inflammatory Diseases: Incidence, Prevalence, Natural History, and Comorbidities J Rheumatol Suppl, May 1, 2010; 85(0): 2 - 10. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Feigenbaum and L. Longstaff Management of the Metabolic Syndrome in Patients With Human Immunodeficiency Virus The Diabetes Educator, May 1, 2010; 36(3): 457 - 464. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. J. Homko, L. Zamora, W. P. Santamore, A. Kashem, T. McConnell, and A. A. Bove Gender Differences in Cardiovascular Risk Factors and Risk Perception Among Individuals With Diabetes The Diabetes Educator, May 1, 2010; 36(3): 483 - 488. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. M. Johnson and D. A. Dowe The Detection of Any Coronary Calcium Outperforms Framingham Risk Score as a First Step in Screening for Coronary Atherosclerosis Am. J. Roentgenol., May 1, 2010; 194(5): 1235 - 1243. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Maganti, V. H. Rigolin, M. E. Sarano, and R. O. Bonow Valvular Heart Disease: Diagnosis and Management Mayo Clin. Proc., May 1, 2010; 85(5): 483 - 500. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. S. Brown, I. C. Armstrong, A. Wang, J. R. Walker, R. J. Noveck, D. Swearingen, M. Allison, J. C. Kissling, J. Kisicki, and D. E. Salazar Effect of the Bile Acid Sequestrant Colesevelam on the Pharmacokinetics of Pioglitazone, Repaglinide, Estrogen Estradiol, Norethindrone, Levothyroxine, and Glyburide J. Clin. Pharmacol., May 1, 2010; 50(5): 554 - 565. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. M. Lloyd-Jones Cardiovascular Risk Prediction: Basic Concepts, Current Status, and Future Directions Circulation, April 20, 2010; 121(15): 1768 - 1777. [Full Text] [PDF]
|
|
|
|
|
|
D. Calvet, E. Touze, O. Varenne, J. L. Sablayrolles, S. Weber, and J. L. Mas Prevalence of Asymptomatic Coronary Artery Disease in Ischemic Stroke Patients: The PRECORIS Study Circulation, April 13, 2010; 121(14): 1623 - 1629. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Rubinshtein, E. H. Yang, C. S. Rihal, A. Prasad, R. J. Lennon, P. J. Best, L. O. Lerman, and A. Lerman Coronary microcirculatory vasodilator function in relation to risk factors among patients without obstructive coronary disease and low to intermediate Framingham score Eur. Heart J., April 2, 2010; 31(8): 936 - 942. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Y. Cheng, D. Dey, B. Tamarappoo, R. Nakazato, H. Gransar, R. Miranda-Peats, A. Ramesh, N. D. Wong, L. J. Shaw, P. J. Slomka, et al. Pericardial Fat Burden on ECG-Gated Noncontrast CT in Asymptomatic Patients Who Subsequently Experience Adverse Cardiovascular Events J. Am. Coll. Cardiol. Img., April 1, 2010; 3(4): 352 - 360. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. V. L. De Socio, C. Martinelli, E. Ricci, G. Orofino, L. Valsecchi, P. Vitiello, L. Martinelli, T. Quirino, P. Maggi, P. Bonfanti, et al. Relations between cardiovascular risk estimates and subclinical atherosclerosis in naive HIV patients: results from the HERMES study Int J STD AIDS, April 1, 2010; 21(4): 267 - 272. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. F. Dominiczak, S. Herget-Rosenthal, C. Delles, D. Fliser, I. Fournier, A. Graber, M. Girolami, E. Holmes, F. Lang, F. Molina, et al. Systems biology to battle vascular disease Nephrol. Dial. Transplant., April 1, 2010; 25(4): 1019 - 1022. [Full Text] [PDF]
|
|
|
|
|
|
B. G. Nordestgaard, A. S. Adourian, J. J. Freiberg, Y. Guo, P. Muntendam, and E. Falk Risk Factors for Near-Term Myocardial Infarction in Apparently Healthy Men and Women Clin. Chem., April 1, 2010; 56(4): 559 - 567. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. E. Toms, V. F. Panoulas, K. M. J. Douglas, H. Griffiths, N. Sattar, J. P. Smith, D. P. M. Symmons, P. Nightingale, G. S. Metsios, and G. D. Kitas Statin use in rheumatoid arthritis in relation to actual cardiovascular risk: evidence for substantial undertreatment of lipid-associated cardiovascular risk? Ann Rheum Dis, April 1, 2010; 69(4): 683 - 688. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. A. Eagle, G. S. Ginsburg, K. Musunuru, W. C. Aird, R. S. Balaban, S. K. Bennett, R. S. Blumenthal, S. R. Coughlin, K. W. Davidson, E. D. Frohlich, et al. Identifying Patients at High Risk of a Cardiovascular Event in the Near Future: Current Status and Future Directions: Report of a National Heart, Lung, and Blood Institute Working Group Circulation, March 30, 2010; 121(12): 1447 - 1454. [Full Text] [PDF]
|
|
|
|
|
|
J. S. Berger, C. O. Jordan, D. Lloyd-Jones, and R. S. Blumenthal Screening for Cardiovascular Risk in Asymptomatic Patients J. Am. Coll. Cardiol., March 23, 2010; 55(12): 1169 - 1177. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. E. Bowen Coronary Heart Disease From a Life-Course Approach: Findings From the Health and Retirement Study, 1998-2004 J Aging Health, March 1, 2010; 22(2): 219 - 241. [Abstract] [PDF]
|
|
|
|
|
|
J. Hsia, R. J. Rodabough, J. E. Manson, S. Liu, M. S. Freiberg, W. Graettinger, M. C. Rosal, B. Cochrane, D. Lloyd-Jones, J. G. Robinson, et al. Evaluation of the American Heart Association Cardiovascular Disease Prevention Guideline for Women Circ Cardiovasc Qual Outcomes, March 1, 2010; 3(2): 128 - 134. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. H.W. Rutten, F. U.S. Mattace-Raso, E. W. Steyerberg, J. Lindemans, A. Hofman, R. G. Wieberdink, M. M.B. Breteler, J. C.M. Witteman, and A. H. van den Meiracker Amino-Terminal Pro-B-Type Natriuretic Peptide Improves Cardiovascular and Cerebrovascular Risk Prediction in the Population: The Rotterdam Study Hypertension, March 1, 2010; 55(3): 785 - 791. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. M. Psaty Drug Therapies for the Primary Prevention of Cardiovascular Events: Trials and Errors: 2009 Ancel Keys Memorial Lecture Circulation, February 23, 2010; 121(7): 940 - 945. [Full Text] [PDF]
|
|
|
|
|
|
WRITING GROUP MEMBERS, D. Lloyd-Jones, R. J. Adams, T. M. Brown, M. Carnethon, S. Dai, G. De Simone, T. B. Ferguson, E. Ford, K. Furie, et al. Heart Disease and Stroke Statistics--2010 Update: A Report From the American Heart Association Circulation, February 23, 2010; 121(7): e46 - e215. [Full Text] [PDF]
|
|
|
|
|
|
G. E. Palomaki, S. Melillo, and L. A. Bradley Association Between 9p21 Genomic Markers and Heart Disease: A Meta-analysis JAMA, February 17, 2010; 303(7): 648 - 656. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Ahmad and S. Mora Providing Patients With Global Cardiovascular Risk Information: Is Knowledge Power? Arch Intern Med, February 8, 2010; 170(3): 227 - 228. [Full Text] [PDF]
|
|
|
|
 |
|
 T. Chimonas, V. G. Athyros, E. Ganotakis, V. Nicolaou, D. B. Panagiotakos, D. P. Mikhailidis, M. Elisaf, and Assessing the Treatment Effect in Metabolic Syndro Cardiovascular Risk Factors and Estimated 10-Year Risk of Fatal Cardiovascular Events Using Various Equations in Greeks With Metabolic Syndrome Angiology, February 1, 2010; 61(1): 49 - 57. [Abstract] [PDF]
|
|
|
|
 |
|
 J. H. Stengard, G. Dyson, R. Frikke-Schmidt, A. Tybjaerg-Hansen, B. G. Nordestgaard, and C. F. Sing Context-Dependent Associations Between Variation in Risk of Ischemic Heart Disease and Variation in the 5' Promoter Region of the Apolipoprotein E Gene in Danish Women Circ Cardiovasc Genet, February 1, 2010; 3(1): 22 - 30. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. D. Almeida, E. B. Loucks, L. Kubzansky, J. Pruessner, J. Maselko, M. J. Meaney, and S. L. Buka Quality of Parental Emotional Care and Calculated Risk for Coronary Heart Disease Psychosom Med, February 1, 2010; 72(2): 148 - 155. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. E. Haley, D. L. Roth, G. Howard, and M. M. Safford Caregiving Strain and Estimated Risk for Stroke and Coronary Heart Disease Among Spouse Caregivers: Differential Effects by Race and Sex Stroke, February 1, 2010; 41(2): 331 - 336. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M J L Peters, D P M Symmons, D McCarey, B A C Dijkmans, P Nicola, T K Kvien, I B McInnes, H Haentzschel, M A Gonzalez-Gay, S Provan, et al. EULAR evidence-based recommendations for cardiovascular risk management in patients with rheumatoid arthritis and other forms of inflammatory arthritis Ann Rheum Dis, February 1, 2010; 69(2): 325 - 331. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. B. Araujo, S. A. Hall, P. Ganz, G. R. Chiu, R. C. Rosen, V. Kupelian, T. G. Travison, and J. B. McKinlay Does Erectile Dysfunction Contribute to Cardiovascular Disease Risk Prediction Beyond the Framingham Risk Score? J. Am. Coll. Cardiol., January 26, 2010; 55(4): 350 - 356. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. Kemmler, S. von Stengel, K. Engelke, L. Haberle, and W. A. Kalender Exercise Effects on Bone Mineral Density, Falls, Coronary Risk Factors, and Health Care Costs in Older Women: The Randomized Controlled Senior Fitness and Prevention (SEFIP) Study Arch Intern Med, January 25, 2010; 170(2): 179 - 185. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. J Talmud, A. D Hingorani, J. A Cooper, M. G Marmot, E. J Brunner, M. Kumari, M. Kivimaki, and S. E Humphries Utility of genetic and non-genetic risk factors in prediction of type 2 diabetes: Whitehall II prospective cohort study BMJ, January 14, 2010; 340(jan14_1): b4838 - b4838. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 I. Tabas, A. Tall, and D. Accili The Impact of Macrophage Insulin Resistance on Advanced Atherosclerotic Plaque Progression Circ. Res., January 8, 2010; 106(1): 58 - 67. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Thambisetty, L. Beason-Held, Y. An, M. A. Kraut, and S. M. Resnick APOE {varepsilon}4 Genotype and Longitudinal Changes in Cerebral Blood Flow in Normal Aging Arch Neurol, January 1, 2010; 67(1): 93 - 98. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Z. Metcalfe, A. Cattamanchi, E. Vittinghoff, C. Ho, J. Grinsdale, P. C. Hopewell, L. M. Kawamura, and P. Nahid Evaluation of Quantitative IFN-{gamma} Response for Risk Stratification of Active Tuberculosis Suspects Am. J. Respir. Crit. Care Med., January 1, 2010; 181(1): 87 - 93. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Z. Molnar, A. S. Lazar, A. Lindner, K. Fornadi, M. E. Czira, A. Dunai, R. Zoller, A. Szentkiralyi, L. Rosivall, C. M. Shapiro, et al. Sleep Apnea Is Associated with Cardiovascular Risk Factors among Kidney Transplant Patients Clin. J. Am. Soc. Nephrol., January 1, 2010; 5(1): 125 - 132. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Sydow, S. P. Fortmann, J. M. Fair, A. Varady, M. A. Hlatky, A. S. Go, C. Iribarren, P. S. Tsao, and for the ADVANCE Investigators Distribution of Asymmetric Dimethylarginine among 980 Healthy, Older Adults of Different Ethnicities Clin. Chem., January 1, 2010; 56(1): 111 - 120. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H G Raterman, I C van Eijk, A E Voskuyl, M J L Peters, B A C Dijkmans, V P van Halm, S Simsek, W F Lems, and M T Nurmohamed The metabolic syndrome is amplified in hypothyroid rheumatoid arthritis patients: a cross-sectional study Ann Rheum Dis, January 1, 2010; 69(01): 39 - 42. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Ayer, J. Chhatwal, O. Alagoz, C. E. Kahn Jr, R. W. Woods, and E. S. Burnside Informatics in Radiology: Comparison of Logistic Regression and Artificial Neural Network Models in Breast Cancer Risk Estimation RadioGraphics, January 1, 2010; 30(1): 13 - 22. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Y. Yang, V. Nambi, Z. Tang, S. S. Virani, E. Boerwinkle, R. C. Hoogeveen, B. C. Astor, T. H. Mosley, J. Coresh, L. Chambless, et al. Clinical Implications of JUPITER (Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin) in a U.S. Population Insights From the ARIC (Atherosclerosis Risk in Communities) Study. J. Am. Coll. Cardiol., December 15, 2009; 54(25): 2388 - 2395. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Ladapo, F. A. Jaffer, U. Hoffmann, C. C. Thomson, F. Bamberg, W. Dec, D. M. Cutler, M. C. Weinstein, and G. S. Gazelle Clinical outcomes and cost-effectiveness of coronary computed tomography angiography in the evaluation of patients with chest pain. J. Am. Coll. Cardiol., December 15, 2009; 54(25): 2409 - 2422. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. McGeachie, R. L. B. Ramoni, J. C. Mychaleckyj, K. L. Furie, J. M. Dreyfuss, Y. Liu, D. Herrington, X. Guo, J. A. Lima, W. Post, et al. Integrative Predictive Model of Coronary Artery Calcification in Atherosclerosis Circulation, December 15, 2009; 120(24): 2448 - 2454. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. L. Sacco, M. Khatri, T. Rundek, Q. Xu, H. Gardener, B. Boden-Albala, M. R. Di Tullio, S. Homma, M. S.V. Elkind, and M. C. Paik Improving Global Vascular Risk Prediction With Behavioral and Anthropometric Factors The Multiethnic NOMAS (Northern Manhattan Cohort Study). J. Am. Coll. Cardiol., December 8, 2009; 54(24): 2303 - 2311. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. Tzoulaki, G. Liberopoulos, and J. P. A. Ioannidis Assessment of Claims of Improved Prediction Beyond the Framingham Risk Score JAMA, December 2, 2009; 302(21): 2345 - 2352. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. W. F. Wilson Challenges to Improve Coronary Heart Disease Risk Assessment JAMA, December 2, 2009; 302(21): 2369 - 2370. [Full Text] [PDF]
|
|
|
|
|
|
F. Saab, D. Mukherjee, H. Gurm, A. Motivala, D. Montgomery, E. Kline-Rogers, M. Rubenfire, and K. Eagle Risk Factors in First Presentation Acute Coronary Syndromes (ACS): How Do We Move From Population to Individualized Risk Prediction? Angiology, December 1, 2009; 60(6): 663 - 667. [Abstract] [PDF]
|
|
|
|
|
|
S. Su, J. Zhao, J. D. Bremner, A. H. Miller, W. Tang, M. Bouzyk, H. Snieder, O. Novik, N. Afzal, J. Goldberg, et al. Serotonin Transporter Gene, Depressive Symptoms, and Interleukin-6 Circ Cardiovasc Genet, December 1, 2009; 2(6): 614 - 620. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Ketlogetswe and R. S. Blumenthal Thirty-Year Multivariate Risk Assessment Is a Stronger Predictor of Cardiovascular Disease than the 10-Year Model Clin. Chem., December 1, 2009; 55(12): 2085 - 2087. [Full Text] [PDF]
|
|
|
|
|
|
J. Ma, K. Berra, W. L. Haskell, L. Klieman, S. Hyde, M. W. Smith, L. Xiao, and R. S. Stafford Case Management to Reduce Risk of Cardiovascular Disease in a County Health Care System Arch Intern Med, November 23, 2009; 169(21): 1988 - 1995. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Steenland, S. Tinker, S. Frisbee, A. Ducatman, and V. Vaccarino Association of Perfluorooctanoic Acid and Perfluorooctane Sulfonate With Serum Lipids Among Adults Living Near a Chemical Plant Am. J. Epidemiol., November 15, 2009; 170(10): 1268 - 1278. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. M. Chang, F. Nabi, J. Xu, L. E. Peterson, A. Achari, C. M. Pratt, and J. J. Mahmarian The coronary artery calcium score and stress myocardial perfusion imaging provide independent and complementary prediction of cardiac risk. J. Am. Coll. Cardiol., November 10, 2009; 54(20): 1872 - 1882. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. B. Chen, R. S. Punglia, K. M. Kuntz, P. M. Mauch, and A. K. Ng Cost Effectiveness and Screening Interval of Lipid Screening in Hodgkin's Lymphoma Survivors J. Clin. Oncol., November 10, 2009; 27(32): 5383 - 5389. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Stolzmann, C. Phan, L. Desbiolles, M. Lachat, T. Pfammatter, B. Marincek, M. Prokop, and H. Alkadhi The heart of patients with aortic aneurysms: evidence from cardiac computed tomography Interactive CardioVascular and Thoracic Surgery, November 1, 2009; 9(5): 769 - 773. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. J. Lehman, C. L. Schlett, F. Bamberg, H. Lee, P. Donnelly, L. Shturman, M. F. Kriegel, T. J. Brady, and U. Hoffmann Assessment of Coronary Plaque Progression in Coronary Computed Tomography Angiography Using a Semiquantitative Score J. Am. Coll. Cardiol. Img., November 1, 2009; 2(11): 1262 - 1270. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Suarthana, E. Meijer, D. E Grobbee, and D. Heederik Predicting occupational diseases Occup. Environ. Med., November 1, 2009; 66(11): 713 - 714. [Full Text] [PDF]
|
|