(Circulation. 1995;92:107-112.)
© 1995 American Heart Association, Inc.
Articles |
From the Division of Cardiovascular Surgery (M. Kato, H.-z.B., M. Kaneko, T.U., D.K., K.O.), Division of Diagnostic Imaging (K.S., S.K.), Osaka Prefectural Hospital, Osaka, Japan.
Correspondence to Masaaki Kato, MD, Division of Cardiovascular Surgery, Osaka Prefectural Hospital, 3-1-56 Mandai-higashi, Sumiyoshiku, Osaka 558, Japan.
Background In patients with Stanford type B dissection who have been treated successfully with medical hypotensive therapy during the acute phase, a large number have incurred the risk of surgery during their chronic phases because of enlargement of the dissected aorta. The purpose of this study was to determine the indications for surgical treatment of acute type B dissection by studying chronic-phase enlargements of aortic dissections in patients treated successfully with medical hypotensive therapy during the acute phase.
Methods and Results In 41 patients with type B dissection who had
been treated medically during the acute phase, univariate
and multivariate factor analyses were made to
determine the predominant predictors for chronic-phase enlargement
(
60 mm) of the dissected aorta. Computed tomography was performed
every 4 to 14 months to observe whether there was enlargement of the
maximum aortic diameter. The predominant predictors for aortic
enlargement in the chronic phase were the existence of a maximum aortic
diameter of
40 mm during the acute phase (P<.001) and a
patent primary entry site in the thoracic aorta (P=.001).
The values of actuarial freedom from aortic enlargement for the
patients with a large aortic diameter (
40 mm) during the acute phase
and a patent primary entry site in the thorax at 1, 3, and 5 years were
70%, 29%, and 22%, respectively. No aortic enlargement was observed
in the other patients throughout the entire follow-up period.
Conclusions These data suggest that patients with acute type B
dissection who have a large aortic diameter (
40 mm) and a patent
primary entry site in the thorax should be treated surgically during
the acute phase on the condition that the surgical risk in this phase
is limited.
Key Words: surgery aorta follow-up studies risk factors
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