Donate Help Contact The AHA Sign In Home
American Heart Association
Circulation
Search: search_blue_button Advanced Search
Circulation. 1995;92:2226-2235

This Article
Right arrow Full Text
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Wernovsky, G.
Right arrow Articles by Wessel, D. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wernovsky, G.
Right arrow Articles by Wessel, D. L.

(Circulation. 1995;92:2226-2235.)
© 1995 American Heart Association, Inc.


Articles

Postoperative Course and Hemodynamic Profile After the Arterial Switch Operation in Neonates and Infants

A Comparison of Low-Flow Cardiopulmonary Bypass and Circulatory Arrest

Presented in part at the 65th Scientific Sessions of the American Heart Association, November 16-19, 1992, New Orleans, La.

Gil Wernovsky, MD; David Wypij, PhD; Richard A. Jonas, MD; John E. Mayer, Jr, MD; Frank L. Hanley, MD; Paul R. Hickey, MD; Amy Z. Walsh, RN; Anthony C. Chang, MD; Aldo R. Castañeda, MD, PhD; Jane W. Newburger, MD, MPH; David L. Wessel, MD

From the Departments of Cardiology (G.W., A.Z.W., A.C.C., J.W.N., D.L.W.), Cardiac Surgery (R.A.J., J.E.M., F.L.H., A.R.C.), and Anesthesia (P.R.H.), Children's Hospital; the Departments of Pediatrics (G.W., A.C.C., J.W.N., D.L.W.), Surgery (R.A.J., J.E.M., F.L.H., A.R.C.), and Anesthesia (P.R.H.), Harvard Medical School; and the Department of Biostatistics (D.W.), Harvard School of Public Health, Boston, Mass.

Background The neurological morbidity associated with prolonged periods of circulatory arrest has led some cardiac surgical teams to promote continuous low-flow cardiopulmonary bypass as an alternative strategy. The nonneurological postoperative effects of both techniques have been previously studied only in a limited fashion.

Methods and Results We compared the hemodynamic profile (cardiac index and systemic and pulmonary vascular resistances), intraoperative and postoperative fluid balance, and perioperative course after deep hypothermia and support consisting predominantly of total circulatory arrest or low-flow cardiopulmonary bypass in a randomized, single-center trial. Eligibility criteria included a diagnosis of transposition of the great arteries and a planned arterial switch operation before the age of 3 months. Of the 171 patients, 129 (66 assigned to circulatory arrest and 63 to low-flow bypass) had an intact ventricular septum and 42 (21 assigned to circulatory arrest and 21 to low-flow bypass) had an associated ventricular septal defect. There were 3 (1.8%) hospital deaths. Patients assigned to low-flow bypass had significantly greater weight gain and positive fluid balance compared with patients assigned to circulatory arrest. Despite the increased weight gain in the infants assigned to low-flow bypass, the duration of mechanical ventilation, stay in the intensive care unit, and hospital stay were similar in both groups. Hemodynamic measurements were made in 122 patients. During the first postoperative night, the cardiac index decreased (32.1±15.4%, mean±SD), while pulmonary and systemic vascular resistance increased. The measured cardiac index was <2.0 L · min-1 · m-2 in 23.8% of the patients, with the lowest measurement typically occurring 9 to 12 hours after surgery. Perfusion strategy assignment was not associated with postoperative hemodynamics or other nonneurological postoperative events.

Conclusions After heart surgery in neonates and infants, both low-flow bypass and circulatory arrest perfusion strategies have comparable effects on the nonneurological postoperative course and hemodynamic profile.


Key Words: cardiopulmonary bypass • circulatory arrest • transposition of great vessels • cardiac output • edema




This article has been cited by other articles:


Home page
Ann. Thorac. Surg.Home page
D. L.S. Morales, K. E. Carberry, J. S. Heinle, E. D. McKenzie, C. D. Fraser Jr, and L. K. Diaz
Extubation in the operating room after Fontan's procedure: effect on practice and outcomes.
Ann. Thorac. Surg., August 1, 2008; 86(2): 576 - 581.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
M. A. Scheurer, J. W. Salvin, V. L. Vida, F. Fynn-Thompson, E. A. Bacha, F. A. Pigula, J. E. Mayer Jr, P. J. del Nido, D. L. Wessel, P. C. Laussen, et al.
Survival and clinical course at fontan after stage one palliation with either a modified blalock-taussig shunt or a right ventricle to pulmonary artery conduit.
J. Am. Coll. Cardiol., July 1, 2008; 52(1): 52 - 59.
[Abstract] [Full Text] [PDF]


Home page
Eur. J. Cardiothorac. Surg.Home page
A. J. Rastan, T. Walther, N. A. Alam, I. Daehnert, M. A. Borger, F. W. Mohr, J. Janousek, and M. Kostelka
Moderate versus deep hypothermia for the arterial switch operation -- experience with 100 consecutive patients
Eur. J. Cardiothorac. Surg., April 1, 2008; 33(4): 619 - 625.
[Abstract] [Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
J.-H. Hsu, P. E. Oishi, R. L. Keller, O. Chikovani, T. R. Karl, A. Azakie, I. Adatia, and J. R. Fineman
Perioperative B-type natriuretic peptide levels predict outcome after bidirectional cavopulmonary anastomosis and total cavopulmonary connection.
J. Thorac. Cardiovasc. Surg., April 1, 2008; 135(4): 746 - 753.
[Abstract] [Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
J. W. Newburger, R. A. Jonas, J. Soul, B. D. Kussman, D. C. Bellinger, P. C. Laussen, R. Robertson, J. E. Mayer Jr, P. J. del Nido, E. A. Bacha, et al.
Randomized trial of hematocrit 25% versus 35% during hypothermic cardiopulmonary bypass in infant heart surgery
J. Thorac. Cardiovasc. Surg., February 1, 2008; 135(2): 347 - 354.
[Abstract] [Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
R. Walsh, C. Boyer, J. LaCorte, V. Parnell, C. Sison, D. Chowdhury, and K. Ojamaa
N-terminal B-type natriuretic peptide levels in pediatric patients with congestive heart failure undergoing cardiac surgery
J. Thorac. Cardiovasc. Surg., January 1, 2008; 135(1): 98 - 105.
[Abstract] [Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
O. Chikovani, J.-H. Hsu, R. Keller, T. R. Karl, A. Azakie, I. Adatia, P. Oishi, and J. R. Fineman
B-type natriuretic peptide levels predict outcomes for children on extracorporeal life support after cardiac surgery.
J. Thorac. Cardiovasc. Surg., November 1, 2007; 134(5): 1179 - 1187.
[Abstract] [Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
J.-H. Hsu, R. L. Keller, O. Chikovani, H. Cheng, S. A. Hollander, T. R. Karl, A. Azakie, I. Adatia, P. Oishi, and J. R. Fineman
B-type natriuretic peptide levels predict outcome after neonatal cardiac surgery.
J. Thorac. Cardiovasc. Surg., October 1, 2007; 134(4): 939 - 945.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
J. Li, G. Zhang, L. Benson, H. Holtby, S. Cai, T. Humpl, G. S. Van Arsdell, A. N. Redington, and C. A. Caldarone
Comparison of the Profiles of Postoperative Systemic Hemodynamics and Oxygen Transport in Neonates After the Hybrid or the Norwood Procedure: A Pilot Study
Circulation, September 11, 2007; 116(11_suppl): I-179 - I-187.
[Abstract] [Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
K. D. Bakshi, B. Vaidyanathan, K. R. Sundaram, S. J. Roth, K. Shivaprakasha, S. G. Rao, S. G. Nair, S. Chengode, and R. K. Kumar
Determinants of early outcome after neonatal cardiac surgery in a developing country
J. Thorac. Cardiovasc. Surg., September 1, 2007; 134(3): 765 - 771.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
Z.-X. Jin, J.-J. Zhou, M. Xin, D.-R. Peng, X.-M. Wang, S.-H. Bi, X.-F. Wei, and D.-H. Yi
Postconditioning the Human Heart with Adenosine in Heart Valve Replacement Surgery
Ann. Thorac. Surg., June 1, 2007; 83(6): 2066 - 2072.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
L. Lai, P. C. Laussen, C. L. Cua, D. L. Wessel, J. M. Costello, P. J. del Nido, J. E. Mayer, and R. R. Thiagarajan
Outcomes After Bidirectional Glenn Operation: Blalock-Taussig Shunt Versus Right Ventricle-to-Pulmonary Artery Conduit
Ann. Thorac. Surg., May 1, 2007; 83(5): 1768 - 1773.
[Abstract] [Full Text] [PDF]


Home page
Anesth. Analg.Home page
M. Cannesson, C. Bionda, B. Gostoli, O. Raisky, S. di Filippo, D. Bompard, C. Vedrinne, R. Rousson, J. Ninet, J. Neidecker, et al.
Time Course and Prognostic Value of Plasma B-type Natriuretic Peptide Concentration in Neonates Undergoing the Arterial Switch Operation
Anesth. Analg., May 1, 2007; 104(5): 1059 - 1065.
[Abstract] [Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
J. Li, G. Zhang, B. W. McCrindle, H. Holtby, T. Humpl, S. Cai, C. A. Caldarone, A. N. Redington, and G. S. Van Arsdell
Profiles of hemodynamics and oxygen transport derived by using continuous measured oxygen consumption after the Norwood procedure
J. Thorac. Cardiovasc. Surg., February 1, 2007; 133(2): 441 - 448.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
J. Li, G. Zhang, H. Holtby, T. Humpl, C. A. Caldarone, G. S. Van Arsdell, and A. N. Redington
Adverse Effects of Dopamine on Systemic Hemodynamic Status and Oxygen Transport in Neonates After the Norwood Procedure
J. Am. Coll. Cardiol., November 7, 2006; 48(9): 1859 - 1864.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
A. Laudito, E. M. Graham, M. R. Stroud, V. Bandisode, A. N. Bhat, F. A. Crawford Jr, A. M. Atz, and S. M. Bradley
Complete repair of conotruncal defects with an interatrial communication: oxygenation, hemodynamic status, and early outcome.
Ann. Thorac. Surg., October 1, 2006; 82(4): 1286 - 1291.
[Abstract] [Full Text] [PDF]


Home page
PediatricsHome page
H. G. Piper, J. L. Alexander, A. Shukla, F. Pigula, J. M. Costello, P. C. Laussen, T. Jaksic, and M. S.D. Agus
Real-Time Continuous Glucose Monitoring in Pediatric Patients During and After Cardiac Surgery
Pediatrics, September 1, 2006; 118(3): 1176 - 1184.
[Abstract] [Full Text] [PDF]


Home page
PerfusionHome page
T. Jones and M. Elliott
Paediatric CPB: Bypass in a High Risk Group
Perfusion, July 1, 2006; 21(4): 229 - 233.
[Abstract] [PDF]


Home page
J Am Coll CardiolHome page
M. M.H. Cheung, R. K. Kharbanda, I. E. Konstantinov, M. Shimizu, H. Frndova, J. Li, H. M. Holtby, P. N. Cox, J. F. Smallhorn, G. S. Van Arsdell, et al.
Randomized Controlled Trial of the Effects of Remote Ischemic Preconditioning on Children Undergoing Cardiac Surgery: First Clinical Application in Humans
J. Am. Coll. Cardiol., June 6, 2006; 47(11): 2277 - 2282.
[Abstract] [Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
J. Li, G. Zhang, H. M. Holtby, B. W. McCrindle, S. Cai, T. Humpl, C. A. Caldarone, W. G. Williams, A. N. Redington, and G. S. Van Arsdell
Inclusion of oxygen consumption improves the accuracy of arterial and venous oxygen saturation interpretation after the Norwood procedure
J. Thorac. Cardiovasc. Surg., May 1, 2006; 131(5): 1099 - 1107.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
H. E. Jeffries, W. J. Wells, V. A. Starnes, R. C. Wetzel, and D. Y. Moromisato
Gastrointestinal Morbidity After Norwood Palliation for Hypoplastic Left Heart Syndrome.
Ann. Thorac. Surg., March 1, 2006; 81(3): 982 - 987.
[Abstract] [Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
Disruption of the ventricular myocardial force-frequency relationship after cardiac surgery in children: noninvasive assessment by means of tissue Doppler imaging.
J. Thorac. Cardiovasc. Surg., March 1, 2006; 131(3): 625 - 631.



Home page
J. Thorac. Cardiovasc. Surg.Home page
Alterations in plasma B-type natriuretic peptide levels after repair of congenital heart defects: a potential perioperative marker.
J. Thorac. Cardiovasc. Surg., March 1, 2006; 131(3): 632 - 638.



Home page
PediatricsHome page
S. J. Roth, I. Adatia, G. D. Pearson, and and Members of the Cardiology Group
Summary proceedings from the cardiology group on postoperative cardiac dysfunction.
Pediatrics, March 1, 2006; 117(3 Pt 2): S40 - S46.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
J. M. Schultz, T. Karamlou, J. Swanson, I. Shen, and R. M. Ungerleider
Hypothermic Low-Flow Cardiopulmonary Bypass Impairs Pulmonary and Right Ventricular Function More Than Circulatory Arrest
Ann. Thorac. Surg., February 1, 2006; 81(2): 474 - 480.
[Abstract] [Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
A. S. Mackie, S. J. Roth, and J. W. Newburger
Reply to the Editor
J. Thorac. Cardiovasc. Surg., February 1, 2006; 131(2): 506 - 506.
[Full Text] [PDF]


Home page
J Intensive Care MedHome page
J. M. Simsic, M. Scheurer, J. D. Tobias, J. Berkenbosch, W. Schechter, F. Madera, S. Weinstein, and R. E. Michler
Perioperative effects and safety of nesiritide following cardiac surgery in children.
J Intensive Care Med, January 1, 2006; 21(1): 22 - 26.
[Abstract] [PDF]


Home page
Ann. Thorac. Surg.Home page
C. D. Myers, K. Mattix, R. G. Presson Jr, P. Vijay, D. Maynes, K. N. Litwak, J. W. Brown, and M. D. Rodefeld
Twenty-Four Hour Cardiopulmonary Stability in a Model of Assisted Newborn Fontan Circulation
Ann. Thorac. Surg., January 1, 2006; 81(1): 264 - 271.
[Abstract] [Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
C. L. Dent, J. P. Spaeth, B. V. Jones, S. M. Schwartz, T. A. Glauser, B. Hallinan, J. M. Pearl, P. R. Khoury, and C. D. Kurth
Brain magnetic resonance imaging abnormalities after the Norwood procedure using regional cerebral perfusion
J. Thorac. Cardiovasc. Surg., January 1, 2006; 131(1): 190 - 197.
[Abstract] [Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
C. L. Dent, J. P. Spaeth, B. V. Jones, S. M. Schwartz, T. A. Glauser, B. Hallinan, J. M. Pearl, P. R. Khoury, and C. D. Kurth
Brain magnetic resonance imaging abnormalities after the Norwood procedure using regional cerebral perfusion
J. Thorac. Cardiovasc. Surg., December 1, 2005; 130(6): 1523 - 1530.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
M. Ando, I.-S. Park, N. Wada, and Y. Takahashi
Steroid Supplementation: A Legitimate Pharmacotherapy After Neonatal Open Heart Surgery
Ann. Thorac. Surg., November 1, 2005; 80(5): 1672 - 1678.
[Abstract] [Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
A. S. Mackie, K. L. Booth, J. W. Newburger, K. Gauvreau, S. A. Huang, P. C. Laussen, J. A. DiNardo, P. J. del Nido, J. E. Mayer Jr, R. A. Jonas, et al.
A randomized, double-blind, placebo-controlled pilot trial of triiodothyronine in neonatal heart surgery
J. Thorac. Cardiovasc. Surg., September 1, 2005; 130(3): 810 - 816.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
S. Riphagen, M. McDougall, S. M. Tibby, N. Alphonso, D. Anderson, C. Austin, A. Durward, and I. A. Murdoch
"Early" Delayed Sternal Closure Following Pediatric Cardiac Surgery
Ann. Thorac. Surg., August 1, 2005; 80(2): 678 - 684.
[Abstract] [Full Text] [PDF]


Home page
Br J AnaesthHome page
I. Malagon, K. Hogenbirk, J. van Pelt, M. G. Hazekamp, and J. G. Bovill
Effect of three different anaesthetic agents on the postoperative production of cardiac troponin T in paediatric cardiac surgery
Br. J. Anaesth., June 1, 2005; 94(6): 805 - 809.
[Abstract] [Full Text] [PDF]


Home page
Br J AnaesthHome page
I. Malagon, W. Onkenhout, G. Klok, P. F. H. van der Poel, J. G. Bovill, and M. G. Hazekamp
Gut permeability in paediatric cardiac surgery
Br. J. Anaesth., February 1, 2005; 94(2): 181 - 185.
[Abstract] [Full Text] [PDF]


Home page
Eur. J. Cardiothorac. Surg.Home page
M. Ruel, T. A. Khan, P. Voisine, C. Bianchi, and F. W. Sellke
Vasomotor dysfunction after cardiac surgery
Eur. J. Cardiothorac. Surg., November 1, 2004; 26(5): 1002 - 1014.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
J. Li, A. Hoschtitzky, M. L. Allen, M. J. Elliott, and A. N. Redington
An Analysis of Oxygen Consumption and Oxygen Delivery in Euthermic Infants After Cardiopulmonary Bypass With Modified Ultrafiltration
Ann. Thorac. Surg., October 1, 2004; 78(4): 1389 - 1396.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
S. M. Bradley, J. M. Simsic, T. C. McQuinn, D. M. Habib, G. S. Shirali, and A. M. Atz
Hemodynamic status after the Norwood procedure: A comparison of right ventricle-to-pulmonary artery connection versus modified blalock-taussig shunt
Ann. Thorac. Surg., September 1, 2004; 78(3): 933 - 941.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
C. A. Caldarone, E. W. Barner, L. Wang, M. Karimi, C. E. Mascio, J. M. Hammel, J. L. Segar, C. Du, and T. D. Scholz
Apoptosis-related mitochondrial dysfunction in the early postoperative neonatal lamb heart
Ann. Thorac. Surg., September 1, 2004; 78(3): 948 - 955.
[Abstract] [Full Text] [PDF]


Home page
PerfusionHome page
C. L Cua, T. M Hoffman, R. Taeed, S. Weinstein, D. Gomez, V. F Olshove, and J. M Craenen
Cerebral saturations trend with mixed venous saturations in patients undergoing extracorporeal life support
Perfusion, May 1, 2004; 19(3): 171 - 176.
[Abstract] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
J. Li, E. Stenbog, A. Bush, T. Grofte, A. N. Redington, and D. J. Penny
Insulin-like growth factor 1 improves the relationship between systemic oxygen consumption and delivery in piglets after cardiopulmonary bypass
J. Thorac. Cardiovasc. Surg., May 1, 2004; 127(5): 1436 - 1441.
[Abstract] [Full Text] [PDF]


Home page
HeartHome page
R R Chaturvedi, D Macrae, K L Brown, M Schindler, E C Smith, K B Davis, G Cohen, V Tsang, M Elliott, M de Leval, et al.
Cardiac ECMO for biventricular hearts after paediatric open heart surgery
Heart, May 1, 2004; 90(5): 545 - 551.
[Abstract] [Full Text] [PDF]


Home page
PediatricsHome page
J. M. Bartlett, D. Wypij, D. C. Bellinger, L. A. Rappaport, L. J. Heffner, R. A. Jonas, and J. W. Newburger
Effect of Prenatal Diagnosis on Outcomes in D-Transposition of the Great Arteries
Pediatrics, April 1, 2004; 113(4): e335 - e340.
[Abstract] [Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
M. Karimi, L. X. Wang, J. M. Hammel, C. E. Mascio, M. Abdulhamid, E. W. Barner, T. D. Scholz, J. L. Segar, W. G. Li, S. D. Niles, et al.
Neonatal vulnerability to ischemia and reperfusion: Cardioplegic arrest causes greater myocardial apoptosis in neonatal lambs than in mature lambs
J. Thorac. Cardiovasc. Surg., February 1, 2004; 127(2): 490 - 497.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
S. M. Cottrell, K. P. Morris, P. Davies, D. C. Bellinger, R. A. Jonas, and J. W. Newburger
Early postoperative body temperature and developmental outcome after open heart surgery in infants
Ann. Thorac. Surg., January 1, 2004; 77(1): 66 - 71.
[Abstract] [Full Text] [PDF]


Home page
ChestHome page
C.-H. Yeh, J.-H. S. Pang, Y.-C. Wu, Y.-C. Wang, J.-J. Chu, and P. J. Lin
Differential-Display Polymerase Chain Reaction Identifies Nicotinamide Adenine Dinucleotide-Ubiquinone Oxidoreductase as an Ischemia/Reperfusion-Regulated Gene in Cardiomyocytes
Chest, January 1, 2004; 125(1): 228 - 235.
[Abstract] [Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
D. C. Bellinger, D. Wypij, A. J. duPlessis, L. A. Rappaport, R. A. Jonas, G. Wernovsky, and J. W. Newburger
Neurodevelopmental status at eight years in children with dextro-transposition of the great arteries: The Boston Circulatory Arrest Trial
J. Thorac. Cardiovasc. Surg., November 1, 2003; 126(5): 1385 - 1396.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
V. A. Schroeder, J. M. Pearl, S. M. Schwartz, T. P. Shanley, P. B. Manning, and D. P. Nelson
Combined Steroid Treatment for Congenital Heart Surgery Improves Oxygen Delivery and Reduces Postbypass Inflammatory Mediator Expression
Circulation, June 10, 2003; 107(22): 2823 - 2828.
[Abstract] [Full Text] [PDF]


Home page
Asian Cardiovasc. Thorac. Ann.Home page
M. Wojtalik, G. Sharma, W. Mrowczynski, A. Siwinska, J. Henschke, R. Bartkowski, M. Pawelec-Wojtalik, and M. Piaszczynski
Arterial Switch Operation in Neonates With Complex Congenital Heart Defects
Asian Cardiovasc Thorac Ann, March 1, 2003; 11(1): 14 - 17.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
T. M. Hoffman, G. Wernovsky, A. M. Atz, T. J. Kulik, D. P. Nelson, A. C. Chang, J. M. Bailey, A. Akbary, J. F. Kocsis, R. Kaczmarek, et al.
Efficacy and Safety of Milrinone in Preventing Low Cardiac Output Syndrome in Infants and Children After Corrective Surgery for Congenital Heart Disease
Circulation, February 25, 2003; 107(7): 996 - 1002.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
I. Shen, C. Giacomuzzi, and R. M. Ungerleider
Current strategies for optimizing the use of cardiopulmonary bypass in neonates and infants
Ann. Thorac. Surg., February 1, 2003; 75(2): S729 - 734.
[Abstract] [Full Text] [PDF]


Home page
Arch. Dis. Child.Home page
S M Tibby and I A Murdoch
Monitoring cardiac function in intensive care
Arch. Dis. Child., January 1, 2003; 88(1): 46 - 52.
[Abstract] [Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
H. H. Hovels-Gurich, J. F. Vazquez-Jimenez, A. Silvestri, K. Schumacher, R. Minkenberg, J. Duchateau, B. J. Messmer, G. von Bernuth, and M.-C. Seghaye
Production of proinflammatory cytokines and myocardial dysfunction after arterial switch operation in neonates with transposition of the great arteries
J. Thorac. Cardiovasc. Surg., October 1, 2002; 124(4): 811 - 820.
[Abstract] [Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
P. Tassani, A. Barankay, F. Haas, S. U. Paek, M. Heilmaier, J. Hess, R. Lange, and J. A. Richter
Cardiac surgery with deep hypothermic circulatory arrest produces less systemic inflammatory response than low-flow cardiopulmonary bypass in newborns
J. Thorac. Cardiovasc. Surg., April 1, 2002; 123(4): 648 - 654.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
D. P. Nelson, S. Burns Wechsler, T. Miura, A. Stagg, J. W. Newburger, J. E. Mayer Jr, and E. J. Neufeld
Myocardial immediate early gene activation after cardiopulmonary bypass with cardiac ischemia-reperfusion
Ann. Thorac. Surg., January 1, 2002; 73(1): 156 - 162.
[Abstract] [Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page