Donate Help Contact The AHA Sign In Home
American Heart Association
Circulation
Search: search_blue_button Advanced Search
Circulation. 1995;92:3464-3472

This Article
Right arrow Full Text
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Vandervoort, P. M.
Right arrow Articles by Thomas, J. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Vandervoort, P. M.
Right arrow Articles by Thomas, J. D.

(Circulation. 1995;92:3464-3472.)
© 1995 American Heart Association, Inc.


Articles

Pressure Recovery in Bileaflet Heart Valve Prostheses

Localized High Velocities and Gradients in Central and Side Orifices With Implications for Doppler-Catheter Gradient Relation in Aortic and Mitral Position

Pieter M. Vandervoort, MD; Neil L. Greenberg, MSE; Min Pu, MD; Kimerly A. Powell, PhD; Delos M. Cosgrove, MD; James D. Thomas, MD

From the Cardiovascular Imaging Center, Departments of Cardiology (P.M.V., M.P., J.D.T.), Biomedical Engineering (N.L.G., K.A.P.), and Thoracic and Cardiovascular Surgery (D.M.C.), Cleveland Clinic Foundation, Cleveland, Ohio.

Correspondence to Pieter M. Vandervoort, MD, Department of Cardiology, Desk F15, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH.

Background We investigate pressure recovery in central and side orifices of St Jude valves and the effect of mitral versus aortic position on the relation between Doppler- and catheter-derived pressure gradients.

Methods and Results Maximum, transvalvular, and net pressure gradients are calculated and compared with Doppler-derived gradients in an in vitro model. Pressure recovery and pressure loss coefficients are calculated. Simultaneous Doppler and catheter gradients are obtained intraoperatively in five patients undergoing mitral valve replacement. Centerline Doppler gradients correspond closely with maximum catheter gradients but are higher than transvalvular and net pressure gradients. Thirty-six percent of the initial pressure drop is recovered between the valve leaflets and is independent of valve size or configuration. A variable amount of postvalvular pressure recovery is observed depending on aortic or mitral configuration. Side orifice velocities are 85±4% of the centerline velocities. Incorporation of the pressure loss coefficient in the simplified Bernoulli equation shows close agreement between centerline Doppler gradients and transvalvular gradients (r=.99, y=1.11x-0.19).

Conclusions Gradients across the St Jude valve measured by Doppler ultrasound are higher than transvalvular or net catheter gradients due to downstream pressure recovery. This is more marked for Doppler gradients based on centerline velocities than side orifice velocities and is more pronounced for valves in an aortic than a mitral configuration. Therefore, to be comparable with invasive transvalvular catheter gradients, either Doppler gradients should be calculated based on side orifice velocity measurements or the Doppler gradient calculation should include the pressure loss coefficient when based on central orifice velocities.


Key Words: prothesis • valves • pressure




This article has been cited by other articles:


Home page
J Am Coll CardiolHome page
J. D. Thomas and Z. B. Popovic
Assessment of Left Ventricular Function by Cardiac Ultrasound
J. Am. Coll. Cardiol., November 21, 2006; 48(10): 2012 - 2025.
[Abstract] [Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
M. Ruel, H. Al-Faleh, A. Kulik, K. L. Chan, T. G. Mesana, and I. G. Burwash
Prosthesis-patient mismatch after aortic valve replacement predominantly affects patients with preexisting left ventricular dysfunction: Effect on survival, freedom from heart failure, and left ventricular mass regression
J. Thorac. Cardiovasc. Surg., May 1, 2006; 131(5): 1036 - 1044.
[Abstract] [Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
C. Amarelli, A. Della Corte, G. Romano, G. Iasevoli, G. Dialetto, L. S. De Santo, M. De Feo, M. Torella, M. Scardone, and M. Cotrufo
Left ventricular mass regression after aortic valve replacement with 17-mm St Jude Medical mechanical prostheses in isolated aortic stenosis
J. Thorac. Cardiovasc. Surg., March 1, 2005; 129(3): 512 - 517.
[Abstract] [Full Text] [PDF]


Home page
ANGIOLOGYHome page
G. R. Rezaian, K. Aghasadeghi, and J. Kojuri
Evaluation of the Hemodynamic Performance of St.Jude Mitral Prostheses: A Pilot Study by Dobutamine-Stress Doppler Echocardiography
Angiology, January 1, 2005; 56(1): 81 - 86.
[Abstract] [PDF]


Home page
Am. J. Physiol. Heart Circ. Physiol.Home page
K. E. Richards, D. Deserranno, E. Donal, N. L. Greenberg, J. D. Thomas, and M. J. Garcia
Influence of structural geometry on the severity of bicuspid aortic stenosis
Am J Physiol Heart Circ Physiol, September 1, 2004; 287(3): H1410 - H1416.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
J. M. Albes, M. Hartrumpf, V. Rudolph, T. Krempl, E. Huttemann, R. Vollandt, and T. Wahlers
Are mechanical valves with enhanced inner diameter advantageous in the small sized aortic annulus?
Ann. Thorac. Surg., November 1, 2003; 76(5): 1564 - 1570.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
J. Teijeira
Omniscience valve results: letter 2
Ann. Thorac. Surg., August 1, 2003; 76(2): 659 - 659.
[Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
M. A. Vannan and K. Sarkar
Assessment of mechanical aortic valve prosthesis by means of Doppler echocardiography: what to measure and why?
J. Thorac. Cardiovasc. Surg., August 1, 2003; 126(2): 317 - 320.
[Full Text] [PDF]


Home page
J Am Coll CardiolHome page
D. Garcia, J. G. Dumesnil, L.-G. Durand, L. Kadem, and P. Pibarot
Discrepancies between catheter and Doppler estimates of valve effective orifice area can be predicted from the pressure recovery phenomenon: practical implications with regard to quantification of aortic stenosis severity
J. Am. Coll. Cardiol., February 5, 2003; 41(3): 435 - 442.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
R. A. Levine and E. Schwammenthal
Stenosis is in the eye of the observer: impact of pressure recovery on assessing aortic valve area
J. Am. Coll. Cardiol., February 5, 2003; 41(3): 443 - 445.
[Full Text] [PDF]


Home page
J Am Coll CardiolHome page
D. Gilon, E. G. Cape, M. D. Handschumacher, J.-K. Song, J. Solheim, M. VanAuker, M. E. E. King, and R. A. Levine
Effect of three-dimensional valve shape on the hemodynamics of aortic stenosis: Three-dimensional echocardiographic stereolithography and patient studies
J. Am. Coll. Cardiol., October 16, 2002; 40(8): 1479 - 1486.
[Abstract] [Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
O. Bech-Hanssen, K. Caidahl, I. Wallentin, P. Ask, and B. Wranne
Assessment of effective orifice area of prosthetic aortic valves with Doppler echocardiography: An in vivo and in vitro study
J. Thorac. Cardiovasc. Surg., August 1, 2001; 122(2): 287 - 295.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
M. S. Firstenberg, P. M. Vandervoort, N. L. Greenberg, N. G. Smedira, P. M. McCarthy, M. J. Garcia, and J. D. Thomas
Noninvasive estimation of transmitral pressure drop across the normal mitral valve in humans: importance of convective and inertial forces during left ventricular filling
J. Am. Coll. Cardiol., November 15, 2000; 36(6): 1942 - 1949.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
P. Pibarot and J. G. Dumesnil
Hemodynamic and clinical impact of prosthesis-patient mismatch in the aortic valve position and its prevention
J. Am. Coll. Cardiol., October 1, 2000; 36(4): 1131 - 1141.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
R. Shandas, J. Kwon, and L. Valdes-Cruz
A Method for Determining the Reference Effective Flow Areas for Mechanical Heart Valve Prostheses : In Vitro Validation Studies
Circulation, April 25, 2000; 101(16): 1953 - 1959.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
D. Y. Leung, J. Wong, L. Rodriguez, M. Pu, P. M. Vandervoort, and J. D. Thomas
Application of Color Doppler Flow Mapping to Calculate Orifice Area of St Jude Mitral Valve
Circulation, September 22, 1998; 98(12): 1205 - 1211.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
R. H. Marcus, R. S. Heinrich, J. Bednarz, S. Lupovitch, J. Abruzzo, R. Borok, B. Vandenberg, R. E. Kerber, W. Piccione, A. P. Yoganathan, et al.
Assessment of Small-Diameter Aortic Mechanical Prostheses : Physiological Relevance of the Doppler Gradient, Utility of Flow Augmentation, and Limitations of Orifice Area Estimation
Circulation, September 1, 1998; 98(9): 866 - 872.
[Abstract] [Full Text] [PDF]