Circulation, Vol 85, 123-129, Copyright © 1992 by American Heart Association
RG Grifka, MP O'Laughlin, MR Nihill and CE Mullins
BACKGROUND. Eight patients with severe congenital mitral stenosis underwent
double transseptal, double-balloon valvuloplasty; two had isolated
congenital mitral stenosis, six had additional cardiac defects, and one had
previous surgical valvotomy. Ages ranged from 0.6 to 36 years (median, 9
years). METHODS AND RESULTS. All procedures were tolerated well. After
valvuloplasty, the left atrial a wave minus the left ventricular
end-diastolic pressure (LVEDP) gradient was reduced from 25 +/- 6 mm Hg to
9 +/- 3 mm Hg (p less than 0.001), the mitral valve mean gradient was
reduced from 18 +/- 7 mm Hg to 8 +/- 3 mm Hg (p = 0.003), and the LVEDP was
unchanged. All patients had marked clinical improvement. Only one patient
developed significant mitral regurgitation. Two of the first four patients
underwent repeat balloon valvuloplasty 7 months later. Follow-up evaluation
on six patients from 4 to 54 months revealed no recurrence of symptoms or
increased mitral regurgitation. CONCLUSIONS. Double transseptal,
double-balloon valvuloplasty is an effective treatment for many forms of
congenital mitral stenosis. Mitral regurgitation is uncommon after this
procedure. The double transseptal approach results in less trauma to the
atrial septum and femoral veins and allows easy assessment of any residual
postvalvuloplasty gradient.
ARTICLES
Double-transseptal, double-balloon valvuloplasty for congenital mitral stenosis
Lillie Frank Abercrombie Section of Pediatric Cardiology, Department of Pediatrics, Baylor College of Medicine, Houston, TX.
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