Circulation, Vol 82, 1106-1116, Copyright © 1990 by American Heart Association
SE Coplen, EM Antman, JA Berlin, P Hewitt and TC Chalmers
Because individual studies evaluating the role of quinidine in the
maintenance of sinus rhythm after cardioversion from chronic atrial
fibrillation have involved relatively few patients, a meta-analysis of
randomized control trials was performed. Six trials published between 1970
and 1984 were selected by two blinded reviewers based on study design and
statistical analysis. Data from these six trials involving 808 patients
were pooled after testing for homogeneity of treatment effects across
trials. Life table estimates of the percent of patients still in sinus
rhythm at 3, 6, and 12 months after cardioversion were constructed for
quinidine and control groups. The proportion of patients remaining in sinus
rhythm in the quinidine group was 69%, 58%, and 50% at 3, 6, and 12 months
postcardioversion respectively. The proportion of patients remaining in
sinus rhythm in the control group was 45%, 33%, and 25% at the same time
intervals. The pooled rate difference, or difference in proportion of
patients in sinus rhythm between quinidine and control groups, was 24%,
23%, and 24% at 3, 6, and 12 months of follow-up (p less than 0.001 at all
time intervals). The unadjusted total mortality rate in the
quinidine-treated patients was 2.9% and in the control group was 0.8%. The
odds of dying in the quinidine-treated group were approximately three times
that of the control group ("typical" odds ratio = 2.98, p less than 0.05).
Thus, quinidine treatment is more effective than no antiarrhythmic therapy
in suppressing recurrences of atrial fibrillation but appears to be
associated with increased total mortality.
ARTICLES
Efficacy and safety of quinidine therapy for maintenance of sinus rhythm after cardioversion. A meta-analysis of randomized control trials [published erratum appears in Circulation 1991 Feb;83(2):714]
Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
This article has been cited by other articles:
 |
|
 |
|
  J.-Y. Le Heuzey The risk of antiarrhythmic drugs in atrial fibrillation: 20 years of controversies Europace, July 1, 2009; 11(7): 840 - 841. [Full Text] [PDF]
|
|
|
|
 |
|
 A. S. Barth and G. F. Tomaselli Cardiac Metabolism and Arrhythmias Circ Arrhythm Electrophysiol, June 1, 2009; 2(3): 327 - 335. [Full Text] [PDF]
|
|
|
|
 |
|
 S. A. Hunt, W. T. Abraham, M. H. Chin, A. M. Feldman, G. S. Francis, T. G. Ganiats, M. Jessup, M. A. Konstam, D. M. Mancini, K. Michl, et al. 2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines Developed in Collaboration With the International Society for Heart and Lung Transplantation J. Am. Coll. Cardiol., April 14, 2009; 53(15): e1 - e90. [Full Text] [PDF]
|
|
|
|
|
|
M. Jessup, W. T. Abraham, D. E. Casey, A. M. Feldman, G. S. Francis, T. G. Ganiats, M. A. Konstam, D. M. Mancini, P. S. Rahko, M. A. Silver, et al. 2009 Focused Update: ACCF/AHA Guidelines for the Diagnosis and Management of Heart Failure in Adults: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines Developed in Collaboration With the International Society for Heart and Lung Transplantation J. Am. Coll. Cardiol., April 14, 2009; 53(15): 1343 - 1382. [Full Text] [PDF]
|
|
|
|
 |
|
 2009 WRITING GROUP TO REVIEW NEW EVIDENCE AND UPDA, M. Jessup, W. T. Abraham, D. E. Casey, A. M. Feldman, G. S. Francis, T. G. Ganiats, M. A. Konstam, D. M. Mancini, P. S. Rahko, et al. 2009 Focused Update: ACCF/AHA Guidelines for the Diagnosis and Management of Heart Failure in Adults: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines: Developed in Collaboration With the International Society for Heart and Lung Transplantation Circulation, April 14, 2009; 119(14): 1977 - 2016. [Full Text] [PDF]
|
|
|
|
|
|
2005 WRITING COMMITTEE MEMBERS, S. A. Hunt, W. T. Abraham, M. H. Chin, A. M. Feldman, G. S. Francis, T. G. Ganiats, M. Jessup, M. A. Konstam, D. M. Mancini, et al. 2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines: Developed in Collaboration With the International Society for Heart and Lung Transplantation Circulation, April 14, 2009; 119(14): e391 - e479. [Full Text] [PDF]
|
|
|
|
 |
|
 D. Roy, M. Talajic, S. Nattel, D. G. Wyse, P. Dorian, K. L. Lee, M. G. Bourassa, J. M. O. Arnold, A. E. Buxton, A. J. Camm, et al. Rhythm Control versus Rate Control for Atrial Fibrillation and Heart Failure N. Engl. J. Med., June 19, 2008; 358(25): 2667 - 2677. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Koistinen, M. Valtonen, J. Savola, and J. Airaksinen Thoracoscopic microwave ablation of atrial fibrillation Interactive CardioVascular and Thoracic Surgery, December 1, 2007; 6(6): 695 - 698. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. N. Singh, S. J. Connolly, H. J.G.M. Crijns, D. Roy, P. R. Kowey, A. Capucci, D. Radzik, E. M. Aliot, S. H. Hohnloser, and the EURIDIS and ADONIS Investigators Dronedarone for Maintenance of Sinus Rhythm in Atrial Fibrillation or Flutter N. Engl. J. Med., September 6, 2007; 357(10): 987 - 999. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. H. Hohnloser and E. N. Prystowsky CRT-D use in heart failure: too little or too much? Eur. Heart J. Suppl., September 1, 2007; 9(suppl_G): G9 - G16. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. M. Roden, P. Kannankeril, and D. Darbar On the relationship among QT interval, atrial fibrillation, and torsade de pointes Europace, September 1, 2007; 9(suppl_4): iv1 - iv3. [Full Text] [PDF]
|
|
|
|
|
|
E. Shantsila, T. Watson, and G. Y. Lip Drug-induced QT-interval prolongation and proarrhythmic risk in the treatment of atrial arrhythmias Europace, September 1, 2007; 9(suppl_4): iv37 - iv44. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. K Nergardh, M. Rosenqvist, R. Nordlander, and M. Frick Maintenance of sinus rhythm with metoprolol CR initiated before cardioversion and repeated cardioversion of atrial fibrillation: a randomized double-blind placebo-controlled study Eur. Heart J., June 1, 2007; 28(11): 1351 - 1357. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Gupta, M. J Earley, G. A Haywood, L. Richmond, M. Fitzgerald, P. Kojodjojo, S. C Sporton, N. S Peters, P. Broadhurst, R. J Schilling, et al. Can atrial fibrillation with a coarse electrocardiographic appearance be treated with catheter ablation of the tricuspid valve-inferior vena cava isthmus? Results of a multicentre randomised controlled trial Heart, June 1, 2007; 93(6): 688 - 693. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Writing Committee Members, V. Fuster, L. E. Ryden, D. S. Cannom, H. J. Crijns, A. B. Curtis, K. A. Ellenbogen, J. L. Halperin, J.-Y. Le Heuzey, G. N. Kay, et al. ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation: full text: A report of the American College of Cardiology/American Heart Association Task Force on practice guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Revise the 2001 Guidelines for the Management of Patients With Atrial Fibrillation) Developed in collaboration with the European Heart Rhythm Association and the Heart Rhythm Society Europace, September 1, 2006; 8(9): 651 - 745. [Full Text] [PDF]
|
|
|
|
|
|
V. Fuster, L. E. Ryden, D. S. Cannom, H. J. Crijns, A. B. Curtis, K. A. Ellenbogen, J. L. Halperin, J.-Y. Le Heuzey, G. N. Kay, J. E. Lowe, et al. ACC/AHA/ESC 2006 Guidelines for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Revise the 2001 Guidelines for the Management of Patients With Atrial Fibrillation) Developed in Collaboration With the European Heart Rhythm Association and the Heart Rhythm Society J. Am. Coll. Cardiol., August 15, 2006; 48(4): e149 - e246. [Full Text] [PDF]
|
|
|
|
|
|
V. Fuster, L. E. Ryden, D. S. Cannom, H. J. Crijns, A. B. Curtis, K. A. Ellenbogen, J. L. Halperin, J.-Y. Le Heuzey, G. N. Kay, J. E. Lowe, et al. ACC/AHA/ESC 2006 Guidelines for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Revise the 2001 Guidelines for the Management of Patients With Atrial Fibrillation): Developed in Collaboration With the European Heart Rhythm Association and the Heart Rhythm Society Circulation, August 15, 2006; 114(7): e257 - e354. [Full Text] [PDF]
|
|
|
|
 |
|
 C. Lafuente-Lafuente, S. Mouly, M. A. Longas-Tejero, I. Mahe, and J.-F. Bergmann Antiarrhythmic drugs for maintaining sinus rhythm after cardioversion of atrial fibrillation: a systematic review of randomized controlled trials. Arch Intern Med, April 10, 2006; 166(7): 719 - 728. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Z. Goldberger and R. Lampert Implantable Cardioverter-Defibrillators: Expanding Indications and Technologies JAMA, February 15, 2006; 295(7): 809 - 818. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M C S Hall and D M Todd Modern management of arrhythmias Postgrad. Med. J., February 1, 2006; 82(964): 117 - 125. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. P. Roose and M. Miyazaki Pharmacologic Treatment of Depression in Patients With Heart Disease Psychosom Med, May 1, 2005; 67(Supplement_1): S54 - S57. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Shelton Prevention of atrial fibrillation after cardioversion: results of the PAFAC trial Eur. Heart J., December 1, 2004; 25(23): 2174 - 2174. [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Kang, B. J. Daly, and J.-S. Kim Uncertainty and Its Antecedents in Patients With A trial Fibrillation West J Nurs Res, November 1, 2004; 26(7): 770 - 783. [Abstract] [PDF]
|
|
|
|
|
|
E. S. Kaufman, P. A. Zimmermann, T. Wang, G. W. Dennish III, P. D. Barrell, M. L. Chandler, H. L. Greene, and AFFIRM Investigators Risk of proarrhythmic events in the atrial fibrillation follow-up investigation of rhythm management (AFFIRM) study: A multivariate analysis J. Am. Coll. Cardiol., September 15, 2004; 44(6): 1276 - 1282. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Fetsch, P. Bauer, R. Engberding, H. P. Koch, J. Lukl, T. Meinertz, M. Oeff, L. Seipel, H. J. Trappe, N. Treese, et al. Prevention of atrial fibrillation after cardioversion: results of the PAFAC trial Eur. Heart J., August 2, 2004; 25(16): 1385 - 1394. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Patten, R. Maas, P. Bauer, B. Luderitz, F. Sonntag, M. Dluzniewski, R. Hatala, G. Opolski, H.-W. Muller, T. Meinertz, et al. Suppression of paroxysmal atrial tachyarrhythmias -- results of the SOPAT trial Eur. Heart J., August 2, 2004; 25(16): 1395 - 1404. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Opolski, A. Torbicki, D. A. Kosior, M. Szulc, B. Wozakowska-Kaplon, P. Kolodziej, and P. Achremczyk Rate Control vs Rhythm Control in Patients With Nonvalvular Persistent Atrial Fibrillation: The Results of the Polish How to Treat Chronic Atrial Fibrillation (HOT CAFE) Study Chest, August 1, 2004; 126(2): 476 - 486. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. K Anthony and V. F Mauro Rate Versus Rhythm Control in Atrial Fibrillation Ann. Pharmacother., May 1, 2004; 38(5): 839 - 844. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Stellbrink, U. Nixdorff, T. Hofmann, W. Lehmacher, W. G. Daniel, P. Hanrath, C. Geller, A. Mugge, W. Sehnert, C. Schmidt-Lucke, et al. Safety and Efficacy of Enoxaparin Compared With Unfractionated Heparin and Oral Anticoagulants for Prevention of Thromboembolic Complications in Cardioversion of Nonvalvular Atrial Fibrillation: The Anticoagulation in Cardioversion using Enoxaparin (ACE) Trial Circulation, March 2, 2004; 109(8): 997 - 1003. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. E. Kochiadakis, N. E. Igoumenidis, M. I. Hamilos, P. G. Tzerakis, N. C. Klapsinos, E. A. Zacharis, and P. E. Vardas Long-term Maintenance of Normal Sinus Rhythm in Patients With Current Symptomatic Atrial Fibrillation: Amiodarone vs Propafenone, Both in Low Doses Chest, February 1, 2004; 125(2): 377 - 383. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. C. Fang, R. S. Stafford, J. N. Ruskin, and D. E. Singer National Trends in Antiarrhythmic and Antithrombotic Medication Use in Atrial Fibrillation Arch Intern Med, January 12, 2004; 164(1): 55 - 60. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. L. McNamara, L. J. Tamariz, J. B. Segal, and E. B. Bass Management of Atrial Fibrillation: Review of the Evidence for the Role of Pharmacologic Therapy, Electrical Cardioversion, and Echocardiography Ann Intern Med, December 16, 2003; 139(12): 1018 - 1033. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Schuetz, C.J. Schulze, K.K. Sarvanakis, H. Mair, H. Plazer, E. Kilger, B. Reichart, and S.M. Wildhirt Surgical treatment of permanent atrial fibrillation using microwave energy ablation: a prospective randomized clinical trial Eur. J. Cardiothorac. Surg., October 1, 2003; 24(4): 475 - 480. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. M. Prasad, H. S. Maniar, M. D. Diodato, R. B. Schuessler, and R. J. Damiano Jr Physiological consequences of bipolar radiofrequency energy on the atria and pulmonary veins: a chronic animal study Ann. Thorac. Surg., September 1, 2003; 76(3): 836 - 842. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Capucci and D. Aschieri Antiarrhythmic drug therapy: what is certain and what is to come Eur. Heart J. Suppl., September 1, 2003; 5(suppl_H): H8 - H18. [Abstract] [PDF]
|
|
|
|
|
|
S. M. Al-Khatib, N. M. A. LaPointe, J. M. Kramer, and R. M. Califf What Clinicians Should Know About the QT Interval JAMA, April 23, 2003; 289(16): 2120 - 2127. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Shinagawa, A. Shiroshita-Takeshita, G. Schram, and S. Nattel Effects of Antiarrhythmic Drugs on Fibrillation in the Remodeled Atrium: Insights Into the Mechanism of the Superior Efficacy of Amiodarone Circulation, March 18, 2003; 107(10): 1440 - 1446. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. lost, L. Virag, A. Varro, and J. Gy. Papp Comparison of the Effect of Class IA Antiarrhythmic Drugs on Transmembrane Potassium Currents in Rabbit Ventricular Myocytes Journal of Cardiovascular Pharmacology and Therapeutics, March 1, 2003; 8(1): 31 - 41. [Abstract] [PDF]
|
|
|
|
|
|
G. Gronefeld and S. H. Hohnloser Rhythm or Rate Control in Atrial Fibrillation: Insights from the Randomized Controlled Trials Journal of Cardiovascular Pharmacology and Therapeutics, March 1, 2003; 8(1_suppl): S39 - S44. [Abstract] [PDF]
|
|
|
|
|
|
I. F. Lozano, A. Vincent, J. Roda, M. Méndez, J. M. M. Ferrer, F. Andrade, J. J. Manzano, R. Ceres, J. Errejon, and J. Toquero Paroxysmal atrial fibrillation prevention by pacing in patients with pacemaker indication Europace, January 1, 2003; 5(3): 267 - 273. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. C. Van Gelder, V. E. Hagens, H. A. Bosker, J. H. Kingma, O. Kamp, T. Kingma, S. A. Said, J. I. Darmanata, A. J.M. Timmermans, J. G.P. Tijssen, et al. A Comparison of Rate Control and Rhythm Control in Patients with Recurrent Persistent Atrial Fibrillation N. Engl. J. Med., December 5, 2002; 347(23): 1834 - 1840. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Khairy and S. Nattel New insights into the mechanisms and management of atrial fibrillation Can. Med. Assoc. J., October 29, 2002; 167(9): 1012 - 1020. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C-K Wong, H D White, R G Wilcox, D A Criger, R M Califf, E J Topol, and E M Ohman Management and outcome of patients with atrial fibrillation during acute myocardial infarction: the GUSTO-III experience Heart, October 1, 2002; 88(4): 357 - 362. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y Blaauw, I C Van Gelder, and H J G M Crijns Treatment of atrial fibrillation Heart, October 1, 2002; 88(4): 432 - 437. [Full Text] [PDF]
|
|
|
|
|
|
B. N. Singh Antiarrhythmic Drugs in Cardiac Arrest Resuscitation: Intravenous Amiodarone or Intravenous Lidocaine? Journal of Cardiovascular Pharmacology and Therapeutics, June 1, 2002; 7(2): 61 - 64. [PDF]
|
|
|
|
 |
|
 W. S. Aronow Management of the Older Person With Atrial Fibrillation J. Gerontol. A Biol. Sci. Med. Sci., June 1, 2002; 57(6): M352 - 363. [Abstract] [Full Text]
|
|
|
|
|
|
G Nichol, F McAlister, B Pham, A Laupacis, B Shea, M Green, A Tang, and G Wells Meta-analysis of randomised controlled trials of the effectiveness of antiarrhythmic agents at promoting sinus rhythm in patients with atrial fibrillation Heart, June 1, 2002; 87(6): 535 - 543. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G Breithardt, H Kuhn, D Hammel, H.-H Scheld, L Seipel, and D. Bocker Cardiac resynchronization therapy into the next decade: from the past to morbidity/mortality trials Eur. Heart J. Suppl., April 1, 2002; 4(suppl_D): D102 - D110. [Abstract] [PDF]
|
|
|
|
 |
|
 E. MARBAN, H.B. NUSS, and J.K. DONAHUE Gene Therapy for Cardiac Arrhythmias Cold Spring Harb Symp Quant Biol, January 1, 2002; 67(0): 527 - 532. [Abstract] [PDF]
|
|
|
|
|
|
A. R. J. Mitchell, P. A. R. Spurrell, K. Kamalvand, M. Higson, R. Shanmuganathan, N. R. Patel, and N. Sulke What is the optimal electrode configuration for atrial defibrillators in man? Europace, January 1, 2002; 4(1): 41 - 44. [Full Text] [PDF]
|
|
|
|
|
|
J. Galperin, M. V. Elizari, P. A. Chiale, R. T. Molina, R. Ledesma, A. O. Scapin, and M. V. Blanco Efficacy of Amiodarone for the Termination of Chronic Atrial Fibrillation and Maintenance of Normal Sinus Rhythm: A Prospective, Multicenter, Randomized, Controlled, Double Blind Trial Journal of Cardiovascular Pharmacology and Therapeutics, December 1, 2001; 6(4): 341 - 350. [Abstract] [PDF]
|
|
|
|
 |
|
 G.Y.H. Lip and F.L. L. S. Hee Paroxysmal atrial fibrillation QJM, December 1, 2001; 94(12): 665 - 678. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Capucci, G.Q. Villani, N. Marrazzo, and M. Piepoli The complementary role of drug, ablation and device in the electrical therapy of atrial fibrillation Eur. Heart J. Suppl., November 1, 2001; 3(suppl_P): P47 - P52. [Abstract] [PDF]
|
|
|
|
|
|
R. C. Ziegelstein Depression in Patients Recovering From a Myocardial Infarction JAMA, October 3, 2001; 286(13): 1621 - 1627. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Guidelines for the management of patients with atrial fibrillation. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines and Policy Conferences (Committee to develop guidelines for the management of patients with atrial fibrillation) developed in collaboration with the North American Society of Pacing and Electrophysiology Eur. Heart J., October 2, 2001; 22(20): 1852 - 1923. [PDF]
|
|
|
|
|
|
V. Fuster, L. E. Ryden, R. W. Asinger, D. S. Cannom, H. J. Crijns, R. L. Frye, J. L. Halperin, G. N. Kay, W. W. Klein, S. Levy, et al. ACC/AHA/ESC guidelines for the management of patients with atrial fibrillation: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines and Policy Conferences (Committee to Develop Guidelines for the Management of Patients With Atrial Fibrillation) Developed in Collaboration With the North American Society of Pacing and Electrophysiology J. Am. Coll. Cardiol., October 1, 2001; 38(4): 1266 - 1266. [Full Text] [PDF]
|
|
|
|
|
|
B. Darpo Spectrum of drugs prolonging QT interval and the incidence of torsades de pointes Eur. Heart J. Suppl., September 1, 2001; 3(suppl_K): K70 - K80. [Abstract] [PDF]
|
|
|
|
|
|
A Plewan, G Lehmann, G Ndrepepa, J Schreieck, E.U Alt, A Schomig, and C Schmitt Maintenance of sinus rhythm after electrical cardioversion of persistent atrial fibrillation. Sotalol vs bisoprolol Eur. Heart J., August 2, 2001; 22(16): 1504 - 1510. [Abstract] [PDF]
|
|
|
|
|
|
J. A. Reiffel and G. Appel Importance of QT Interval Determination and Renal Function Assessment During Antiarrhythmic Drug Therapy Journal of Cardiovascular Pharmacology and Therapeutics, June 1, 2001; 6(2): 111 - 119. [Abstract] [PDF]
|
|
|
|
|
|
E. Raanani, A. Albage, T. E. David, T. M. Yau, and S. Armstrong The efficacy of the Cox/maze procedure combined with mitral valve surgery: a matched control study Eur. J. Cardiothorac. Surg., April 1, 2001; 19(4): 438 - 442. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. N. Singh and J. S. M. Sarma Mechanisms of Action of Antiarrhythmic Drugs Relative to the Origin and Perpetuation of Cardiac Arrhythmias Journal of Cardiovascular Pharmacology and Therapeutics, March 1, 2001; 6(1): 69 - 87. [PDF]
|
|
|
|
|
|
F. Lombardi, A. Colombo, B. Basilico, R. Ravaglia, M. Garbin, D. Vergani, P. M. Battezzati, and C. Fiorentini Heart rate variability and early recurrence of atrial fibrillation after electrical cardioversion J. Am. Coll. Cardiol., January 1, 2001; 37(1): 157 - 162. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X. Zheng, M. E. Benser, G. P. Walcott, S. D. Girouard, D. L. Rollins, W. M. Smith, and R. E. Ideker Reduction of Atrial Defibrillation Threshold With an Interatrial Septal Electrode Circulation, November 21, 2000; 102(21): 2659 - 2664. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Singh, R. G. Zoble, L. Yellen, M. A. Brodsky, G. K. Feld, M. Berk, and C. B. Billing Jr Efficacy and Safety of Oral Dofetilide in Converting to and Maintaining Sinus Rhythm in Patients With Chronic Atrial Fibrillation or Atrial Flutter : The Symptomatic Atrial Fibrillation Investigative Research on Dofetilide (SAFIRE-D) Study Circulation, November 7, 2000; 102(19): 2385 - 2390. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. M. Tracy, M. Akhtar, J. P. DiMarco, D. L. Packer, H. H. Weitz, W. L. Winters, J. L. Achord, A. W. Boone, J. W. Hirshfeld Jr, B. H. Lorell, et al. American College of Cardiology/American Heart Association Clinical Competence Statement on invasive electrophysiology studies, catheter ablation, and cardioversion: A report of the american college of cardiology/american heart association/american college of physicians-american society of internal medicine task force on clinical competence J. Am. Coll. Cardiol., November 1, 2000; 36(5): 1725 - 1736. [Full Text] [PDF]
|
|
|
|
|
|
P. Dorian, W. Jung, D. Newman, M. Paquette, K. Wood, G. M. Ayers, J. Camm, M. Akhtar, and B. Luderitz The impairment of health-related quality of life in patients with intermittent atrial fibrillation: implications for the assessment of investigational therapy J. Am. Coll. Cardiol., October 1, 2000; 36(4): 1303 - 1309. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Mathew, S. Hunsberger, J. Fleg, F. Mc Sherry, W. Williford, and S. Yusuf Incidence, Predictive Factors, and Prognostic Significance of Supraventricular Tachyarrhythmias in Congestive Heart Failure Chest, October 1, 2000; 118(4): 914 - 922. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G E Kochiadakis, N E Igoumenidis, M E Marketou, M D Kaleboubas, E N Simantirakis, and P E Vardas Low dose amiodarone and sotalol in the treatment of recurrent, symptomatic atrial fibrillation: a comparative, placebo controlled study Heart, September 1, 2000; 84(3): 251 - 257. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. M Roden ELECTROPHYSIOLOGY: Antiarrhythmic drugs: from mechanisms to clinical practice Heart, September 1, 2000; 84(3): 339 - 346. [Full Text] [PDF]
|
|
|
|
|
|
C. Torp-Pedersen, M. Moller, L. Kober, and A.J. Camm Dofetilide for the treatment of atrial fibrillation in patients with congestive heart failure Eur. Heart J., August 1, 2000; 21(15): 1204 - 1206. [PDF]
|
|
|
|
|
|
M. Frick, B. Darpo, J. Ostergren, and M. Rosenqvist The effect of oral magnesium, alone or as an adjuvant to sotalol, after cardioversion in patients with persistent atrial fibrillation Eur. Heart J., July 2, 2000; 21(14): 1177 - 1185. [Abstract] [PDF]
|
|
|
|
|
|
V. Kuhlkamp, A. Schirdewan, K. Stangl, M. Homberg, M. Ploch, and O. A. Beck Use of metoprolol CR/XL to maintain sinus rhythm after conversion from persistent atrial fibrillation: A randomized, double-blind, placebo-controlled study J. Am. Coll. Cardiol., July 1, 2000; 36(1): 139 - 146. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Zebe Atrial fibrillation in dialysis patients Nephrol. Dial. Transplant., June 1, 2000; 15(6): 765 - 768. [Full Text] [PDF]
|
|
|
|
|
|
D. Roy, M. Talajic, P. Dorian, S. Connolly, M. J. Eisenberg, M. Green, T. Kus, J. Lambert, M. Dubuc, P. Gagne, et al. Amiodarone to Prevent Recurrence of Atrial Fibrillation N. Engl. J. Med., March 30, 2000; 342(13): 913 - 920. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H Nakazawa, D.A Lythall, J Noh, N Ishikawa, K Sugino, K Ito, and S.M.C Hardman Is there a place for the late cardioversion of atrial fibrillation?. A long-term follow-up study of patients with post-thyrotoxic atrial fibrillation Eur. Heart J., February 2, 2000; 21(4): 327 - 333. [Abstract] [PDF]
|
|
|
|
|
|
A Capucci, G.Q Villani, D Aschieri, A Rosi, and M.F Piepoli Oral amiodarone increases the efficacy of direct-current cardioversion in restoration of sinus rhythm in patients with chronic atrial fibrillation Eur. Heart J., January 1, 2000; 21(1): 66 - 73. [Abstract] [PDF]
|
|
|
|
|
|
S. H. Hohnloser, Y.-G. Li, B. Bender, and G. Gronefeld Review : Pharmacological Management of Atrial Fibrillation: An Update Journal of Cardiovascular Pharmacology and Therapeutics, January 1, 2000; 5(1): 11 - 16. [Abstract] [PDF]
|
|
|
|
|
|
T. A. Burkart and A. B. Curtis Reviews: Atrial Fibrillation: Current and Future Strategies for Management Journal of Cardiovascular Pharmacology and Therapeutics, January 1, 2000; 5(3): 151 - 160. [PDF]
|
|
|
|
|
|
S. J. Connolly Evidence-Based Analysis of Amiodarone Efficacy and Safety Circulation, November 9, 1999; 100(19): 2025 - 2034. [Full Text] [PDF]
|
|
|
|
 |
|
 N. Handa, H. V. Schaff, J. J. Morris, B. J. Anderson, S. L. Kopecky, and M. Enriquez-Sarano OUTCOME OF VALVE REPAIR AND THE COX MAZE PROCEDURE FOR MITRAL REGURGITATION AND ASSOCIATED ATRIAL FIBRILLATION J. Thorac. Cardiovasc. Surg., October 1, 1999; 118(4): 628 - 635. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A E Tuinenburg, I C Van Gelder, M P V. Den Berg, J Brugemann, P J De Kam, and H J G M Crijns Lack of prevention of heart failure by serial electrical cardioversion in patients with persistent atrial fibrillation Heart, October 1, 1999; 82(4): 486 - 493. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Torp-Pedersen, M. Moller, P. E. Bloch-Thomsen, L. Kober, E. Sandoe, K. Egstrup, E. Agner, J. Carlsen, J. Videbak, B. Marchant, et al. Dofetilide in Patients with Congestive Heart Failure and Left Ventricular Dysfunction N. Engl. J. Med., September 16, 1999; 341(12): 857 - 865. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. G. Stevenson and L. W. Stevenson Atrial Fibrillation in Heart Failure N. Engl. J. Med., September 16, 1999; 341(12): 910 - 911. [Full Text]
|
|
|
|
|
|
K. Kamalvand, K. Tan, G. Lloyd, J. Gill, C. Bucknall, and N. Sulke Alterations in atrial electrophysiology associated with chronic atrial fibrillation in man Eur. Heart J., June 2, 1999; 20(12): 888 - 895. [Abstract] [PDF]
|
|
|
|
|
|
R. Lee, T. Nitta, R. B. Schuessler, D. C. Johnson, J. P. Boineau, and J. L. Cox The closed heart MAZE: a nonbypass surgical technique Ann. Thorac. Surg., June 1, 1999; 67(6): 1696 - 1702. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Catherwood, W. D. Fitzpatrick, M. L. Greenberg, P. T. Holzberger, D. J. Malenka, B. R. Gerling, and J. D. Birkmeyer Cost-Effectiveness of Cardioversion and Antiarrhythmic Therapy in Nonvalvular Atrial Fibrillation Ann Intern Med, April 20, 1999; 130(8): 625 - 636. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. G. Pauker and M. H. Eckman Finding What You Seek: Analyzing Therapies for Nonvalvular Atrial Fibrillation Ann Intern Med, April 20, 1999; 130(8): 690 - 691. [Full Text] [PDF]
|
|
|
|
|
|
C.-P. Lau, H.-F. Tse, and G. M. Ayers Defibrillation-guided radiofrequency ablation of atrial fibrillation secondary to an atrial focus J. Am. Coll. Cardiol., April 1, 1999; 33(5): 1217 - 1226. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I.A Paraskevaidis, G.N Theodorakis, D.G Katritsis, D.P Tsiapras, E.G Livanis, and D.T Kremastinos Pulmonary vein flow analysis by transoesophageal echocardiography in patients with chronic atrial fibrillation; 1 year follow-up after cardioversion Eur. Heart J., March 1, 1999; 20(5): 375 - 385. [Abstract] [PDF]
|
|
|
|
|
|
G. B. J. Mancini and M. Schulzer Reporting Risks and Benefits of Therapy by Use of the Concepts of Unqualified Success and Unmitigated Failure : Applications to Highly Cited Trials in Cardiovascular Medicine Circulation, January 26, 1999; 99(3): 377 - 383. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Valderrabano and B. N. Singh Review : Electrophysiologic and Antiarrhythmic Effects of Propafenone: Focus on Atrial Fibrillation Journal of Cardiovascular Pharmacology and Therapeutics, January 1, 1999; 4(3): 183 - 198. [PDF]
|
|
|
|
|
|
S. Riva, C. Tondo, C. Carbucicchio, P. Galimberti, G. Fassini, and P. Della Bella Incidence and clinical significance of transformation of atrial fibrillation to atrial flutter in patients undergoing long-term antiarrhythmic drug treatment Europace, January 1, 1999; 1(4): 242 - 247. [Abstract] [PDF]
|
|
|
|
|
|
C. Pandozi, L. Bianconi, M. Villani, G. Gentilucci, A. Castro, G. Altamura, A. P. Jesi, F. Lamberti, F. Ammirati, and M. Santini Electrophysiological Characteristics of the Human Atria After Cardioversion of Persistent Atrial Fibrillation Circulation, December 22, 1998; 98(25): 2860 - 2865. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. C. Deedwania, B. N. Singh, K. Ellenbogen, S. Fisher, R. Fletcher, and S. N. Singh Spontaneous Conversion and Maintenance of Sinus Rhythm by Amiodarone in Patients With Heart Failure and Atrial Fibrillation : Observations from the Veterans Affairs Congestive Heart Failure Survival Trial of Antiarrhythmic Therapy (CHF-STAT) Circulation, December 8, 1998; 98(23): 2574 - 2579. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Delfaut, S. Saksena, A. Prakash, and R. B. Krol Long-term outcome of patients with drug-refractory atrial flutter and fibrillation after single- and dual-site right atrial pacing for arrhythmia prevention J. Am. Coll. Cardiol., December 1, 1998; 32(7): 1900 - 1908. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. S. Stafford, D. C. Robson, B. Misra, J. Ruskin, and D. E. Singer Rate Control and Sinus Rhythm Maintenance in Atrial Fibrillation: National Trends in Medication Use, 1980-1996 Arch Intern Med, October 26, 1998; 158(19): 2144 - 2148. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Liebold, A. Wahba, and D. E. Birnbaum Low-Energy Cardioversion With Epicardial Wire Electrodes: New Treatment of Atrial Fibrillation After Open Heart Surgery Circulation, September 1, 1998; 98(9): 883 - 886. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. H. Eckman, R. H. Falk, and S. G. Pauker Cost-effectiveness of Therapies for Patients With Nonvalvular Atrial Fibrillation Arch Intern Med, August 10, 1998; 158(15): 1669 - 1677. [Abstract] [Full Text]
|
|