Circulation, Vol 76, 262-265, Copyright © 1987 by American Heart Association
T Akasaka, J Yoshikawa, K Yoshida, F Okumachi, K Koizumi, K Shiratori, S Takao, M Shakudo and H Kato
To assess the prevalence of valvular regurgitation in the aged, we studied
176 apparently healthy volunteers with no history or physical evidence of
cardiac abnormality. Their ages ranged from 40 to 90 (66 +/- 14, mean +/-
SD) years. We examined these subjects by pulsed Doppler echocardiography
combined with two-dimensional echocardiography to determine the prevalence
of valvular regurgitation. Regurgitation began to appear in subjects in
their fifties, increasing in prevalence with advancing age (r = .81, p less
than .001), and was documented in all over age 80. Similarly, regurgitation
involving more than one valve appeared in those 60 years and older, and was
very common (89%) in subjects in their eighties. With each type of valvular
regurgitation, the prevalence of each type of regurgitation increased with
aging, but this tendency was most prominent for aortic regurgitation. We
conclude that (1) single or multivalvular regurgitation as detected by
pulsed Doppler echocardiography is very common in the aged and may be
considered a normal finding in the absence of other evidence of heart
disease, and (2) the high prevalence of regurgitation in the aged must be
taken into account when Doppler examinations are being performed.
ARTICLES
Age-related valvular regurgitation: a study by pulsed Doppler echocardiography
This article has been cited by other articles:
![]() |
M. Sandrock, A. Schmidt-Trucksass, D. Schmitz, A. Niess, and H.-H. Dickhuth Influence of Physiologic Cardiac Hypertrophy on the Prevalence of Heart Valve Regurgitation J. Ultrasound Med., January 1, 2008; 27(1): 85 - 93. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. A. Waller, J. Kaplan, and M. G. Heckman Valvular Heart Disease in Patients Taking Pergolide Mayo Clin. Proc., August 1, 2005; 80(8): 1016 - 1020. [Abstract] [PDF] |
||||
![]() |
C. N. Foroulis, C. S. Kotoulas, S. Kakouros, G. Evangelatos, C. Chassapis, M. Konstantinou, and A. G. Lioulias Study on the late effect of pneumonectomy on right heart pressures using Doppler echocardiography Eur. J. Cardiothorac. Surg., September 1, 2004; 26(3): 508 - 514. [Abstract] [Full Text] [PDF] |
||||
![]() |
J D R Thomson Management of valvar aortic stenosis in children Heart, January 1, 2004; 90(1): 5 - 6. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. S. Borer and R. O. Bonow Contemporary Approach to Aortic and Mitral Regurgitation Circulation, November 18, 2003; 108(20): 2432 - 2438. [Full Text] [PDF] |
||||
![]() |
C. DAVIES and D. SAHN Detection and significance of subclinical mitral regurgitation by colour Doppler techniques Heart, April 1, 2001; 85(4): 369 - 370. [Full Text] |
||||
![]() |
J Allen, J D R Thomson, I J Lewis, and J L Gibbs Mitral regurgitation after anthracycline treatment for childhood malignancy Heart, April 1, 2001; 85(4): 430 - 432. [Abstract] [Full Text] |
||||
![]() |
N. E. Lebowitz, J. N. Bella, M. J. Roman, J. E. Liu, D. P. Fishman, M. Paranicas, E. T. Lee, R. R. Fabsitz, T. K. Welty, B. V. Howard, et al. Prevalence and correlates of aortic regurgitation in american indians: the Strong Heart Study J. Am. Coll. Cardiol., August 1, 2000; 36(2): 461 - 467. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. M. Gardin, D. Schumacher, G. Constantine, K. D. Davis, C. Leung, and C. L. Reid Valvular Abnormalities and Cardiovascular Status Following Exposure to Dexfenfluramine or Phentermine/Fenfluramine JAMA, April 5, 2000; 283(13): 1703 - 1709. [Abstract] [Full Text] [PDF] |
||||
![]() |
J D R Thomson, J Allen, and J L Gibbs Left sided valvar regurgitation in normal children and adolescents Heart, February 1, 2000; 83(2): 185 - 187. [Abstract] [Full Text] |
||||
![]() |
R. J. Henning, J. Silva, V. Reddy, S. Kamat, M. B. Morgan, Yong Xiang Li, and S. Chiou Cocaine Increases {beta}-Myosin Heavy-Chain Protein Expression in Cardiac Myocytes Journal of Cardiovascular Pharmacology and Therapeutics, January 1, 2000; 5(4): 313 - 322. [Abstract] [PDF] |
||||
![]() |
M. A. Khan, C. A. Herzog, J. V. St. Peter, G. G. Hartley, R. Madlon-Kay, C. D. Dick, R. W. Asinger, and J. T. Vessey The Prevalence of Cardiac Valvular Insufficiency Assessed by Transthoracic Echocardiography in Obese Patients Treated with Appetite-Suppressant Drugs N. Engl. J. Med., September 10, 1998; 339(11): 713 - 718. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. B. Moisa, S. M. Zeldis, S. A. Alper, and W. C. Scott Aortic Regurgitation in Coronary Artery Bypass Grafting: Implications for Cardioplegia Administration Ann. Thorac. Surg., September 1, 1995; 60(3): 665 - 668. [Abstract] [Full Text] |
||||
![]() |
D. C. Sutton, R. Kluger, S. U. Ahmed, S. C. Reimold, and J. B. Mark Flow reversal in the descending aorta: A guide to intraoperative assessment of aortic regurgitation with transesophageal echocardiography J. Thorac. Cardiovasc. Surg., September 1, 1994; 108(3): 576 - 582. [Abstract] [Full Text] |
||||
![]() |
P. S. Rahko Prevalence of Regurgitant Murmurs in Patients with Valvular Regurgitation Detected by Doppler Echocardiography Ann Intern Med, September 15, 1989; 111(6): 466 - 472. [Abstract] [PDF] |
||||
|
Circulation Home | Subscriptions | Archives | Feedback | Authors | Help | AHA Journals Home | Search Copyright © 1987 American Heart Association, Inc. All rights reserved. Unauthorized use prohibited. |