Circulation, Vol 74, 1399-1406, Copyright © 1986 by American Heart Association
P Pignoli, E Tremoli, A Poli, P Oreste and R Paoletti
A study in vitro of specimens of human aortic and common carotid arteries
was carried out to determine the feasibility of direct measurement (i.e.,
not from residual lumen) of arterial wall thickness with B mode real-time
imaging. Measurements in vivo by the same technique were also obtained from
common carotid arteries of 10 young normal male subjects. Aortic samples
were classified as class A (relatively normal) or class B (with one or more
atherosclerotic plaques). In all class A and 85% of class B arterial
samples a characteristic B mode image composed of two parallel echogenic
lines separated by a hypoechoic space was found. The distance between the
two lines (B mode image of intimal + medial thickness) was measured and
correlated with the thickness of different combinations of tunicae
evaluated by gross and microscopic examination. On the basis of these
findings and the results of dissection experiments on the intima and
adventitia we concluded that results of B mode imaging of intimal + medial
thickness did not differ significantly from the intimal + medial thickness
measured on pathologic examination. With respect to the accuracy of
measurements obtained by B mode imaging as compared with pathologic
findings, we found an error of less than 20% for measurements in 77% of
normal and pathologic aortic walls. In addition, no significant difference
was found between B mode-determined intimal + medial thickness in the
common carotid arteries evaluated in vitro and that determined by this
method in vivo in young subjects, indicating that B mode imaging represents
a useful approach for the measurement of intimal + medial thickness of
human arteries in vivo.
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Intimal plus medial thickness of the arterial wall: a direct measurement with ultrasound imaging
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S. Soljanlahti, T. Autti, K. Lauerma, R. Raininko, P. Keto, H. Turtola, and A. F. Vuorio Familial Hypercholesterolemia Patients Treated With Statins at No Increased Risk for Intracranial Vascular Lesions Despite Increased Cholesterol Burden and Extracranial Atherosclerosis Stroke, July 1, 2005; 36(7): 1572 - 1574. [Abstract] [Full Text] [PDF]
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B. Iglseder, P. Cip, L. Malaimare, G. Ladurner, and B. Paulweber The Metabolic Syndrome Is a Stronger Risk Factor for Early Carotid Atherosclerosis in Women Than in Men Stroke, June 1, 2005; 36(6): 1212 - 1217. [Abstract] [Full Text] [PDF]
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R. S. Reneman, J. M. Meinders, and A. P.G. Hoeks Non-invasive ultrasound in arterial wall dynamics in humans: what have we learned and what remains to be solved Eur. Heart J., May 2, 2005; 26(10): 960 - 966. [Abstract] [Full Text] [PDF]
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N. Gungor, T. Thompson, K. Sutton-Tyrrell, J. Janosky, and S. Arslanian Early Signs of Cardiovascular Disease in Youth With Obesity and Type 2 Diabetes Diabetes Care, May 1, 2005; 28(5): 1219 - 1221. [Full Text] [PDF]
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F. Piarulli, A. Lapolla, G. Sartore, C. Rossetti, G. Bax, M. Noale, N. Minicuci, C. Fiore, L. Marchioro, E. Manzato, et al. Autoantibodies Against Oxidized LDLs and Atherosclerosis in Type 2 Diabetes Diabetes Care, March 1, 2005; 28(3): 653 - 657. [Abstract] [Full Text] [PDF]
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S.-i. Kawachi, N. Takeda, A. Sasaki, Y. Kokubo, K. Takami, H. Sarui, M. Hayashi, N. Yamakita, and K. Yasuda Circulating Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 Are Associated With Early Carotid Atherosclerosis Arterioscler Thromb Vasc Biol, March 1, 2005; 25(3): 617 - 621. [Abstract] [Full Text] [PDF]
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E. D. Beishuizen, M. A. van de Ree, J. W. Jukema, J. T. Tamsma, J. C. M. van der Vijver, A. E. Meinders, H. Putter, and M. V. Huisman Two-Year Statin Therapy Does Not Alter the Progression of Intima-Media Thickness in Patients With Type 2 Diabetes Without Manifest Cardiovascular Disease Diabetes Care, December 1, 2004; 27(12): 2887 - 2892. [Abstract] [Full Text] [PDF]
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Y. Aso, K.-i. Okumura, S. Wakabayashi, K. Takebayashi, S. Taki, and T. Inukai Elevated Pregnancy-Associated Plasma Protein-A in Sera from Type 2 Diabetic Patients with Hypercholesterolemia: Associations with Carotid Atherosclerosis and Toe-Brachial Index J. Clin. Endocrinol. Metab., November 1, 2004; 89(11): 5713 - 5717. [Abstract] [Full Text] [PDF]
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G. K. Hovingh, A. Brownlie, R. J. Bisoendial, M. P. Dube, J. H.M. Levels, W. Petersen, R. P.F. Dullaart, E. S.G. Stroes, A. H. Zwinderman, E. de Groot, et al. A novel apoA-I mutation (L178P) leads to endothelial dysfunction, increased arterial wall thickness, and premature coronary artery disease J. Am. Coll. Cardiol., October 6, 2004; 44(7): 1429 - 1435. [Abstract] [Full Text] [PDF]
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T. Temelkova-Kurktschiev, M. Hanefeld, G. Chinetti, C. Zawadzki, S. Haulon, A. Kubaszek, C. Koehler, W. Leonhardt, B. Staels, and M. Laakso Ala12Ala Genotype of the Peroxisome Proliferator-Activated Receptor {gamma}2 Protects against Atherosclerosis J. Clin. Endocrinol. Metab., September 1, 2004; 89(9): 4238 - 4242. [Abstract] [Full Text] [PDF]
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F. Orio Jr., S. Palomba, T. Cascella, B. De Simone, S. Di Biase, T. Russo, D. Labella, F. Zullo, G. Lombardi, and A. Colao Early Impairment of Endothelial Structure and Function in Young Normal-Weight Women with Polycystic Ovary Syndrome J. Clin. Endocrinol. Metab., September 1, 2004; 89(9): 4588 - 4593. [Abstract] [Full Text] [PDF]
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L. E. Chambless, G. Heiss, E. Shahar, M. J. Earp, and J. Toole Prediction of Ischemic Stroke Risk in the Atherosclerosis Risk in Communities Study Am. J. Epidemiol., August 1, 2004; 160(3): 259 - 269. [Abstract] [Full Text] [PDF]
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M. Rema, V. Mohan, R. Deepa, and R. Ravikumar Association of Carotid Intima-Media Thickness and Arterial Stiffness With Diabetic Retinopathy: The Chennai Urban Rural Epidemiology Study (CURES-2) Diabetes Care, August 1, 2004; 27(8): 1962 - 1967. [Abstract] [Full Text] [PDF]
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G. B. J. Mancini, B. Dahlof, and J. Diez Surrogate Markers for Cardiovascular Disease: Structural Markers Circulation, June 29, 2004; 109(25_suppl_1): IV-22 - IV-30. [Full Text] [PDF]
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E. de Groot, G. K. Hovingh, A. Wiegman, P. Duriez, A. J. Smit, J.-C. Fruchart, and J. J.P. Kastelein Measurement of Arterial Wall Thickness as a Surrogate Marker for Atherosclerosis Circulation, June 15, 2004; 109(23_suppl_1): III-33 - III-38. [Abstract] [Full Text]
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K.-i. Aihara, H. Azuma, N. Takamori, Y. Kanagawa, M. Akaike, M. Fujimura, T. Yoshida, S. Hashizume, M. Kato, H. Yamaguchi, et al. Heparin Cofactor II Is a Novel Protective Factor Against Carotid Atherosclerosis in Elderly Individuals Circulation, June 8, 2004; 109(22): 2761 - 2765. [Abstract] [Full Text] [PDF]
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M. Hanefeld, J. L. Chiasson, C. Koehler, E. Henkel, F. Schaper, and T. Temelkova-Kurktschiev Acarbose Slows Progression of Intima-Media Thickness of the Carotid Arteries in Subjects With Impaired Glucose Tolerance Stroke, May 1, 2004; 35(5): 1073 - 1078. [Abstract] [Full Text] [PDF]
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S. A. Wickline Plaque characterization: surrogate markers or the real thing? J. Am. Coll. Cardiol., April 7, 2004; 43(7): 1185 - 1187. [Full Text] [PDF]
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P. Y. Hsue, J. C. Lo, A. Franklin, A. F. Bolger, J. N. Martin, S. G. Deeks, and D. D. Waters Progression of Atherosclerosis as Assessed by Carotid Intima-Media Thickness in Patients With HIV Infection Circulation, April 6, 2004; 109(13): 1603 - 1608. [Abstract] [Full Text] [PDF]
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A. Sramek, P. Bucciarelli, A.B. Federici, P.M. Mannucci, V. De Rosa, G. Castaman, M. Morfini, M.G. Mazzucconi, A. Rocino, M. Schiavoni, et al. Patients With Type 3 Severe von Willebrand Disease Are Not Protected Against Atherosclerosis: Results From a Multicenter Study in 47 Patients Circulation, February 17, 2004; 109(6): 740 - 744. [Abstract] [Full Text] [PDF]
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