Circulation, Vol 74, 1365-1370, Copyright © 1986 by American Heart Association
PJ de Feyter, PW Serruys, A Soward, M van den Brand, E Bos and PG Hugenholtz
Coronary angioplasty was performed in 53 patients in whom unstable angina
had reoccurred after 48 hr and within 30 days after sustained myocardial
infarction. Single-vessel disease was present in 64% of the patients and
multivessel disease in 36%. The preceding myocardial infarction had been
small to moderate in size in the majority of the patients. The left
ventricular ejection fraction was more than 50% in 80% of the patients.
Forty-five patients were refractory to pharmacologic treatment; eight were
initially stabilized but once again became symptomatic with light exertion.
Angioplasty was performed in 35 patients 2 to 14 days and in 18 patients 15
to 30 days after infarction (average 12 +/- 7 days after infarction). The
initial success rate was 89% (47/53). The success rate of the patients
treated at 2 to 14 days was lower (29/35, 83%) than that of patients
treated at 14 to 30 days (18/18, 100%) but did not reach statistical
significance (p less than .06). There were no deaths related to the
procedure. In four of the six failures, emergency bypass surgery was
performed and two patients sustained a myocardial infarction. Furthermore,
a myocardial infarction complicated the angioplasty procedure in two other
patients; thus the overall procedure-related myocardial infarction rate was
8% (4/53). At 6 months follow-up 26% (14/53) of all the patients who
underwent angioplasty had recurrence of angina, which was successfully
treated with repeat angioplasty, bypass surgery, or medical therapy. There
were no late deaths. Late myocardial infarction occurred in two patients.
Thus the total myocardial infarction rate after angioplasty at 6 months was
11% (6/53 patients).(ABSTRACT TRUNCATED AT 250 WORDS)
ARTICLES
Coronary angioplasty for early postinfarction unstable angina
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