Circulation, Vol 74, 469-476, Copyright © 1986 by American Heart Association
M Cohen and KP Rentrop
We have shown improvement in collateral filling immediately after sudden
controlled coronary occlusion in human subjects undergoing elective
coronary angioplasty. It has been suggested but not proved that collateral
circulation can limit myocardial ischemia. We prospectively studied 23
patients with isolated left anterior descending (n = 14) or right coronary
(n = 9) disease and normal left ventriculograms during elective coronary
angioplasty. A second arterial catheter was used for injection of the
contralateral artery to assess collateral filling before balloon placement
and during coronary occlusion by balloon inflation. Left ventriculography
was performed during another inflation. Grading of collateral filling was
as follows: 0 = none, 1 = filling of side branches only, 2 = partial
filling of the epicardial segment, 3 = complete filling of the epicardial
segment. Indexes of myocardial ischemia included percent of the left
ventricular perimeter showing new hypocontractility and the sum of ST
segment elevation measured on a simultaneous 12-lead electrocardiogram
recorded during each inflation. Collateral filling during balloon occlusion
and indexes of ischemia were assessed at 30 to 40 sec into inflation.
Aortic pressure and heart rate did not correlate with the percent
hypocontractile perimeter nor the sum of ST segment elevation. There was a
significant correlation between the grade of collateral filling during
inflation and both percent hypocontractile perimeter (r = -.85) and the sum
of ST segment elevation (r = -.87). Anginal pain occurred in all patients
with grade 0 or 1 collateral filling but in only 36% of patients with grade
2 or 3 collaterals. In conclusion, collateral circulation limits myocardial
ischemia as assessed by the extent of new ventricular asynergy and
electrocardiographic changes during coronary occlusion in patients.
ARTICLES
Limitation of myocardial ischemia by collateral circulation during sudden controlled coronary artery occlusion in human subjects: a prospective study
This article has been cited by other articles:
 |
|
 |
|
  K. Ishii, T. Suyama, M. Imai, M. Maenaka, A. Yamanaka, Y. Makino, Y. Seino, K. Shimada, and J. Yoshikawa Abnormal regional left ventricular systolic and diastolic function in patients with coronary artery disease undergoing percutaneous coronary intervention: clinical significance of post-ischemic diastolic stunning. J. Am. Coll. Cardiol., October 20, 2009; 54(17): 1589 - 1597. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Dieleman, A.-M. Sauer, C. Klijn, H. Nathoe, K. Moons, C. Kalkman, J. Kappelle, and D. Van Dijk Presence of coronary collaterals is associated with a decreased incidence of cognitive decline after coronary artery bypass surgery Eur. J. Cardiothorac. Surg., January 1, 2009; 35(1): 48 - 53. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Kumbasar, O. Akyurek, I. Dincer, Y. Atmaca, M. Kilickap, C. Erol, and D. Oral Good Collaterals Predict Viable Myocardium Angiology, November 1, 2007; 58(5): 550 - 555. [Abstract] [PDF]
|
|
|
|
|
|
I. Kusama, K. Hibi, M. Kosuge, N. Nozawa, H. Ozaki, H. Yano, S. Sumita, K. Tsukahara, J. Okuda, T. Ebina, et al. Impact of Plaque Rupture on Infarct Size in ST-Segment Elevation Anterior Acute Myocardial Infarction J. Am. Coll. Cardiol., September 25, 2007; 50(13): 1230 - 1237. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Lu, X. Xu, M. Zhang, R. Cao, E. Brakenhielm, C. Li, H. Lin, G. Yao, H. Sun, L. Qi, et al. Combinatorial protein therapy of angiogenic and arteriogenic factors remarkably improves collaterogenesis and cardiac function in pigs PNAS, July 17, 2007; 104(29): 12140 - 12145. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Takami and H. Masumoto Angiographic Fate of Collateral Vessels After Surgical Revascularization of the Totally Occluded Left Anterior Descending Artery Ann. Thorac. Surg., January 1, 2007; 83(1): 120 - 125. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Nakashima, T. Katayama, C. Takagi, K. Amenomori, M. Ishizaki, Y. Honda, and S. Suzuki Obstructive sleep apnoea inhibits the recovery of left ventricular function in patients with acute myocardial infarction Eur. Heart J., October 1, 2006; 27(19): 2317 - 2322. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Zimarino, A. Ausiello, G. Contegiacomo, I. Riccardi, G. Renda, C. Di Iorio, and R. De Caterina Rapid Decline of Collateral Circulation Increases Susceptibility to Myocardial Ischemia: The Trade-Off of Successful Percutaneous Recanalization of Chronic Total Occlusions J. Am. Coll. Cardiol., July 4, 2006; 48(1): 59 - 65. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. F. De Marchi, P. Meier, P. Oswald, and C. Seiler Variable ECG signs of ischemia during controlled occlusion of the left and right coronary artery in humans Am J Physiol Heart Circ Physiol, July 1, 2006; 291(1): H351 - H356. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Wei, K. L. Tong, T. Belcik, P. Rafter, M. Ragosta, X.-Q. Wang, and S. Kaul Detection of Coronary Stenoses at Rest With Myocardial Contrast Echocardiography Circulation, August 23, 2005; 112(8): 1154 - 1160. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C.-W. Cheng, M.-J. Hung, L.-T. Kuo, and W.-J. Cherng Appearance of Collateral Circulation in the Absence of Total Occlusive Spastic Coronary Artery: A Case Report Angiology, May 1, 2005; 56(3): 331 - 334. [Abstract] [PDF]
|
|
|
|
 |
|
 R I Williams, N Payne, T Phillips, J D'hooge, and A G Fraser Strain rate imaging after dynamic stress provides objective evidence of persistent regional myocardial dysfunction in ischaemic myocardium: regional stunning identified? Heart, February 1, 2005; 91(2): 152 - 160. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. M. Nathoe, E. Buskens, E. W.L. Jansen, W. J.L. Suyker, P. R. Stella, J. R. Lahpor, W.-J. van Boven, D. van Dijk, J. C. Diephuis, C. Borst, et al. Role of Coronary Collaterals in Off-Pump and On-Pump Coronary Bypass Surgery Circulation, September 28, 2004; 110(13): 1738 - 1742. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 V. van Weel, M. M.L. Deckers, J. M. Grimbergen, K. J.M. van Leuven, J. H.P. Lardenoye, R. O. Schlingemann, G. P. van Nieuw Amerongen, J. H. van Bockel, V. W.M. van Hinsbergh, and P. H.A. Quax Vascular Endothelial Growth Factor Overexpression in Ischemic Skeletal Muscle Enhances Myoglobin Expression In Vivo Circ. Res., July 9, 2004; 95(1): 58 - 66. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. Aboul-Enein, S. Kar, S. W. Hayes, M. Sciammarella, A. Abidov, R. Makkar, J. D. Friedman, N. Eigler, and D. S. Berman Influence of Angiographic Collateral Circulation on Myocardial Perfusion in Patients with Chronic Total Occlusion of a Single Coronary Artery and No Prior Myocardial Infarction J. Nucl. Med., June 1, 2004; 45(6): 950 - 955. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. S. Werner, U. Emig, O. Mutschke, G. Schwarz, P. Bahrmann, and H. R. Figulla Regression of Collateral Function After Recanalization of Chronic Total Coronary Occlusions: A Serial Assessment by Intracoronary Pressure and Doppler Recordings Circulation, December 9, 2003; 108(23): 2877 - 2882. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y Birnbaum and B J Drew The electrocardiogram in ST elevation acute myocardial infarction: correlation with coronary anatomy and prognosis Postgrad. Med. J., September 1, 2003; 79(935): 490 - 504. [Abstract] [Full Text]
|
|
|
|
|
|
J. Koerselman, Y. van der Graaf, P. P.Th. de Jaegere, and D. E. Grobbee Coronary Collaterals: An Important and Underexposed Aspect of Coronary Artery Disease Circulation, May 20, 2003; 107(19): 2507 - 2511. [Full Text] [PDF]
|
|
|
|
|
|
T. Kukulski, F. Jamal, L. Herbots, J. D'hooge, B. Bijnens, L. Hatle, I. De Scheerder, and G. R. Sutherland Identification of acutely ischemic myocardium using ultrasonic strain measurements: A clinical study in patients undergoing coronary angioplasty J. Am. Coll. Cardiol., March 5, 2003; 41(5): 810 - 819. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N Noto, K Karasawa, H Kanamaru, M Ayusawa, N Sumitomo, T Okada, and K Harada Non-invasive measurement of coronary flow reserve in children with Kawasaki disease Heart, June 1, 2002; 87(6): 559 - 565. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. S. Werner, B. M. Richartz, O. Gastmann, M. Ferrari, and H. R. Figulla Immediate Changes of Collateral Function After Successful Recanalization of Chronic Total Coronary Occlusions Circulation, December 12, 2000; 102(24): 2959 - 2965. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P.W Serruys, J.N Hamburger, J Fajadet, M Haude, H Klues, R Seabra-Gomes, T Corcos, C Hamm, L Pizzuli, B Meier, et al. Total occlusion trial with angioplasty by using laser guidewire. The TOTAL trial Eur. Heart J., November 1, 2000; 21(21): 1797 - 1805. [Abstract] [PDF]
|
|
|
|
|
|
K. Kodama, G. Hiasa, T. Ohtsuka, S. Ikeda, H. Hashida, T. Kuwahara, Y. Hara, Y. Shigematsu, M. Hamada, and K. Hiwada Transient U Wave Inversion During Treadmill Exercise Testing in Patients with Left Anterior Descending Coronary Artery Disease Angiology, July 1, 2000; 51(7): 581 - 589. [Abstract] [PDF]
|
|
|
|
 |
|
 P. R. Sensky, A. Jivan, N. M. Hudson, R. P. Keal, B. Morgan, J. L. Tranter, D. de Bono, N. J. Samani, and G. R. Cherryman Coronary Artery Disease: Combined Stress MR Imaging Protocol-One-Stop Evaluation of Myocardial Perfusion and Function Radiology, May 1, 2000; 215(2): 608 - 614. [Abstract] [Full Text]
|
|
|
|
|
|
N. P. R.o. Sand, M. Rehling, J. P. Bagger, L. Thuesen, C. Flo, and T. T. Nielsen Functional significance of recruitable collaterals during temporary coronary occlusion evaluated by 99mTc-sestamibi single-photon emission computerized tomography J. Am. Coll. Cardiol., March 1, 2000; 35(3): 624 - 632. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Miwa, K. Nakagawa, T. Hirai, and H. Inoue Exercise-induced U-wave alterations as a marker of well-developed and well-functioning collateral vessels in patients with effort angina J. Am. Coll. Cardiol., March 1, 2000; 35(3): 757 - 763. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Tommasi, E. Carluccio, M. Bentivoglio, L. Corea, and E. Picano Low-dose dipyridamole infusion acutely increases exercise capacity in angina pectoris: A double-blind, placebo controlled crossover stress echocardiographic study J. Am. Coll. Cardiol., January 1, 2000; 35(1): 83 - 88. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. A. Remah, H. Asanoi, S. Joho, A. Igawa, T. Kameyama, T. Nozawa, and H. Inoue Modulation of left ventricular diastolic distensibility by collateral flow recruitment during balloon coronary occlusion J. Am. Coll. Cardiol., August 1, 1999; 34(2): 500 - 506. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F Leclercq, P Messner-Pellenc, Q Descours, J-P Daures, J-L Pasquie, F-X Hager, J-M Davy, and R Grolleau-Raoux Combined assessment of reflow and collateral blood flow by myocardial contrast echocardiography after acute reperfused myocardial infarction Heart, July 1, 1999; 82(1): 62 - 67. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Billinger, M. Fleisch, F. R. Eberli, A. Garachemani, B. Meier, and C. Seiler Is the development of myocardial tolerance to repeated ischemia in humans due to preconditioning or to collateral recruitment? J. Am. Coll. Cardiol., March 15, 1999; 33(4): 1027 - 1035. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Nakano, J.-D. Lee, H. Shimizu, T. Tsuchida, Y. Yonekura, Y. Ishii, and T. Ueda Reciprocal ST-segment depression associated with exercise-induced ST-segment elevation indicates residual viability after myocardial infarction J. Am. Coll. Cardiol., March 1, 1999; 33(3): 620 - 626. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Ito, Y. Taniyama, K. Iwakura, N. Nishikawa, T. Masuyama, T. Kuzuya, M. Hori, Y. Higashino, K. Fujii, and T. Minamino Intravenous nicorandil can preserve microvascular integrity and myocardial viability in patients with reperfused anterior wall myocardial infarction J. Am. Coll. Cardiol., March 1, 1999; 33(3): 654 - 660. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. A. M. van Liebergen, J. J. Piek, K. T. Koch, R. J. de Winter, C. E. Schotborgh, and K. I. Lie Quantification of collateral flow in humans: a comparison of angiographic, electrocardiographic and hemodynamic variables J. Am. Coll. Cardiol., March 1, 1999; 33(3): 670 - 677. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T W Koh, G S Carr-White, A C DeSouza, F D Ferdinand, J R Pepper, and D G Gibson Effect of coronary occlusion on left ventricular function with and without collateral supply during beating heart coronary artery surgery Heart, March 1, 1999; 81(3): 285 - 291. [Abstract] [Full Text]
|
|
|
|
|
|
H Yamagishi, K Akioka, M Takagi, A Tanaka, K Takeuchi, J Yoshikawa, and H Ochi Exercise four hour redistribution thallium-201 single photon emission computed tomography and exercise induced ST segment elevation in detecting the viable myocardium in patients with acute myocardial infarction Heart, January 1, 1999; 81(1): 17 - 24. [Abstract] [Full Text]
|
|
|
|
|
|
K. E. J. Airaksinen, K. U. O. Tahvanainen, D. L. Eckberg, M. J. Niemela, A. Ylitalo, and H. V. Huikuri Arterial baroreflex impairment in patients during acute coronary occlusion J. Am. Coll. Cardiol., November 15, 1998; 32(6): 1641 - 1647. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Sakuma, Y. Hayashi, K. Sumii, M. Imazu, and M. Yamakido Prediction of short- and intermediate-term prognoses of patients with acute myocardial infarction using myocardial contrast echocardiography one day after recanalization J. Am. Coll. Cardiol., October 1, 1998; 32(4): 890 - 897. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. K. Kaukoranta, M. V.K. Lepojarvi, K. T. Kiviluoma, K. V. Ylitalo, and K. J. Peuhkurinen Myocardial protection during antegrade versus retrograde cardioplegia Ann. Thorac. Surg., September 1, 1998; 66(3): 755 - 761. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Pamir, N. Caglar, D. Oral, S. M. Aslan, and D. Kumbasar Effect of Coronary Collateral Circulation on Exercise Stress Test Angiology, August 1, 1998; 49(8): 619 - 624. [Abstract] [PDF]
|
|
|
|
|
|
T. Bombardini, E. Picano, and T. Bombardini The Coronary Angiogenetic Effect of Heparin: Experimental Basis and Clinical Evidence Angiology, November 1, 1997; 48(11): 969 - 976. [Abstract] [PDF]
|
|
|
|
|
|
F. Tomai, F. Crea, A. Gaspardone, F. Versaci, A. S. Ghini, R. De Paulis, L. Chiariello, and P. A. Gioffre Phentolamine Prevents Adaptation to Ischemia During Coronary Angioplasty : Role of {alpha}-Adrenergic Receptors in Ischemic Preconditioning Circulation, October 7, 1997; 96(7): 2171 - 2177. [Abstract] [Full Text]
|
|
|
|
|
|
M. Rosseel, P. Dendale, C. De Sadeleer, D. Schoors, P. Block, P.R. Franken, and M. Rosseel Dipyridamole-Induced Angina Pectoris During Sestamibi Stress Test in Patients with Significant Coronary Artery Disease: Clinical, Angiographic, and Nuclear Determinants Angiology, April 1, 1997; 48(4): 301 - 307. [Abstract] [PDF]
|
|
|
|
|
|
H. Matsuo, S. Watanabe, T. Kadosaki, T. Yamaki, S. Tanaka, S. Miyata, T. Segawa, Y. Matsuno, M. Tomita, and H. Fujiwara Validation of Collateral Fractional Flow Reserve by Myocardial Perfusion Imaging Circulation, March 5, 2002; 105(9): 1060 - 1065. [Abstract] [Full Text] [PDF]
|
|