This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Cassidy, D. M. Articles by Josephson, M. E. Search for Related Content PubMed PubMed Citation Articles by Cassidy, D. M. Articles by Josephson, M. E.

Circulation, Vol 73, 645-652, Copyright © 1986 by American Heart Association

ARTICLES

Endocardial catheter mapping in patients in sinus rhythm: relationship to underlying heart disease and ventricular arrhythmias

DM Cassidy, JA Vassallo, JM Miller, DS Poll, AE Buxton, FE Marchlinski and ME Josephson

Catheter mapping during sinus rhythm was performed in 132 patients with coronary artery disease and 26 patients with congestive noncoronary cardiomyopathy. Each of the patients had a clinical history of one of the following: no ventricular arrhythmia, nonsustained ventricular tachycardia, cardiac arrest, or sustained ventricular tachycardia. The characteristics of the endocardial electrogram and other measured indexes of slow endocardial conduction were compared between patients with different types of disease and in different arrhythmia groups to determine if differences existed. The cardiomyopathic group had a higher percent of normal endocardial electrograms than the coronary artery disease group, with no evidence of slow endocardial conduction. The sustained ventricular tachycardia group exhibited a greater percent of abnormal endocardial electrograms and more evidence of slow endocardial conduction, distinguishing this group from the three other arrhythmia groups. We conclude the following: The underlying electrophysiologic substrate varies in patients with different ventricular arrhythmias. It is therefore inappropriate to analyze all patients with ventricular arrhythmias as a single group. Patients with congestive noncoronary cardiomyopathy, regardless of the type of their arrhythmia, have a relatively normal endocardium. Those patients with serious ventricular arrhythmias should not be considered candidates for surgery directed at removing abnormal endocardium.

This article has been cited by other articles:

				H. M. Haqqani, J. M. Kalman, K. C. Roberts-Thomson, R. N. Balasubramaniam, R. Rosso, R. L. Snowdon, P. B. Sparks, J. K. Vohra, and J. B. Morton Fundamental Differences in Electrophysiologic and Electroanatomic Substrate Between Ischemic Cardiomyopathy Patients With and Without Clinical Ventricular Tachycardia J. Am. Coll. Cardiol., July 7, 2009; 54(2): 166 - 173. [Abstract] [Full Text] [PDF]

				J. P. Daubert Why Are (Only) Some Infarcted Hearts Arrhythmogenic? J. Am. Coll. Cardiol., July 7, 2009; 54(2): 174 - 175. [Full Text] [PDF]

				D. Corrado, C. Basso, L. Leoni, B. Tokajuk, P. Turrini, B. Bauce, F. Migliore, A. Pavei, G. Tarantini, M. Napodano, et al. Three-Dimensional Electroanatomical Voltage Mapping and Histologic Evaluation of Myocardial Substrate in Right Ventricular Outflow Tract Tachycardia. J. Am. Coll. Cardiol., February 19, 2008; 51(7): 731 - 739. [Abstract] [Full Text] [PDF]

				F. E. Marchlinski Perivalvular Fibrosis and Monomorphic Ventricular Tachycardia: Toward a Unifying Hypothesis in Nonischemic Cardiomyopathy Circulation, October 30, 2007; 116(18): 1998 - 2001. [Full Text] [PDF]

				D. Corrado, C. Basso, L. Leoni, B. Tokajuk, B. Bauce, G. Frigo, G. Tarantini, M. Napodano, P. Turrini, A. Ramondo, et al. Three-Dimensional Electroanatomic Voltage Mapping Increases Accuracy of Diagnosing Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia Circulation, June 14, 2005; 111(23): 3042 - 3050. [Abstract] [Full Text] [PDF]

				H. H. Hsia, D. J. Callans, and F. E. Marchlinski Characterization of Endocardial Electrophysiological Substrate in Patients With Nonischemic Cardiomyopathy and Monomorphic Ventricular Tachycardia Circulation, August 12, 2003; 108(6): 704 - 710. [Abstract] [Full Text] [PDF]

				A. Arenal, E. Glez-Torrecilla, M. Ortiz, J. Villacastin, J. Fdez-Portales, E. Sousa, S. del Castillo, L. Perez de Isla, J. Jimenez, and J. Almendral Ablation of electrograms with an isolated, delayed component as treatment of unmappable monomorphic ventricular tachycardias in patients with structural heart disease J. Am. Coll. Cardiol., January 1, 2003; 41(1): 81 - 92. [Abstract] [Full Text] [PDF]

				M. Boulos, I. Lashevsky, S. Reisner, and L. Gepstein Electroanatomic mapping of arrhythmogenic right ventricular dysplasia J. Am. Coll. Cardiol., December 1, 2001; 38(7): 2020 - 2027. [Abstract] [Full Text] [PDF]

				F. E. Marchlinski, D. J. Callans, C. D. Gottlieb, and E. Zado Linear Ablation Lesions for Control of Unmappable Ventricular Tachycardia in Patients With Ischemic and Nonischemic Cardiomyopathy Circulation, March 21, 2000; 101(11): 1288 - 1296. [Abstract] [Full Text] [PDF]

				L. Gepstein, A. Goldin, J. Lessick, G. Hayam, S. Shpun, Y. Schwartz, G. Hakim, R. Shofty, A. Turgeman, D. Kirshenbaum, et al. Electromechanical Characterization of Chronic Myocardial Infarction in the Canine Coronary Occlusion Model Circulation, November 10, 1998; 98(19): 2055 - 2064. [Abstract] [Full Text] [PDF]

				P. T. Vaitkus, M. A. Capeless, M. S. Stanton, B. I. Gersh, S. C. Hammill, G. Steinbeck, and D. Andresen Electrophysiologically Guided Antiarrhythmic Therapy versus Beta-Blocker Therapy in Patients with Ventricular Tachyarrhythmias N. Engl. J. Med., February 4, 1993; 328(5): 357 - 358. [Full Text]