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Circulation. 1984;69:1190-1194

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Circulation, Vol 69, 1190-1194, Copyright © 1984 by American Heart Association


ARTICLES

Molecular genetics of lipoprotein disorders

JL Breslow

These types of studies lay the foundation for understanding the human apolipoproteins at the genetic level. In addition, through a few specific examples, we have already shown evidence at the DNA level that lesions in apolipoprotein genes can play a role in human atherosclerosis. This work is in its infancy, but we hope it will have a major impact on our ability to understand genetic susceptibility to atherosclerosis in the general population.