Circulation, Vol 68, 50-58, Copyright © 1983 by American Heart Association
AP Avolio, SG Chen, RP Wang, CL Zhang, MF Li and MF O'Rourke
Pulse wave velocity (PWV) was measured by means of transcutaneous Doppler
techniques in the aorta, right arm, and right leg of 480 normal subjects of
both sexes in urban Beijing, China (age range 3 to 89 years, mean age 41
+/- 20.8 SD); supine blood pressure was recorded in the brachial artery of
each subject with standard sphygmomanometric procedures. Serum cholesterol
was determined in a subgroup of 79 subjects (age 17 to 85 years, mean 47
+/- 26 SD). PWV (y in cm/sec) was found to vary with age (x, years) at each
of the three locations according to the following regression equations:
aorta, y = 9.2x + 615, r = .673 (p less than .001); right arm, y = 4.8x +
998, r = .453 (p less than .001); right leg, y = 5.6x + 791, r = .630 (p
less than .001). Systolic, diastolic, mean, and pulse pressures were found
to increase with age. PWV also increased with mean supine blood pressure
but was not related to serum cholesterol (average 4.49 +/- 0.11 [SEM],
mmol/l). Compared with that of Western populations, serum cholesterol
tended to be lower at all age groups, systolic pressure higher at ages over
35 years, and PWV higher at all ages. Because change in PWV is directly
related to change in arterial compliance, these results indicate that aging
and not concomitant atherosclerosis (known to be rare in Asian populations)
is the dominant factor associated with reduced arterial compliance and
increased left ventricular load in these subjects.
ARTICLES
Effects of aging on changing arterial compliance and left ventricular load in a northern Chinese urban community
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C.-H. Chen, M. Nakayama, M. Talbot, E. Nevo, B. Fetics, G. Gerstenblith, L. C. Becker, and D. A. Kass Verapamil acutely reduces ventricular-vascular stiffening and improves aerobic exercise performance in elderly individuals J. Am. Coll. Cardiol., May 1, 1999; 33(6): 1602 - 1609. [Abstract] [Full Text] [PDF] |
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J. Blacher, R. Asmar, S. Djane, G. M. London, and M. E. Safar Aortic Pulse Wave Velocity as a Marker of Cardiovascular Risk in Hypertensive Patients Hypertension, May 1, 1999; 33(5): 1111 - 1117. [Abstract] [Full Text] [PDF] |
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C.-H. Chen, M. Nakayama, E. Nevo, B. J. Fetics, W. L. Maughan, and D. A. Kass Coupled systolic-ventricular and vascular stiffening with age: Implications for pressure regulation and cardiac reserve in the elderly J. Am. Coll. Cardiol., November 1, 1998; 32(5): 1221 - 1227. [Abstract] [Full Text] [PDF] |
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J. Blacher, B. Pannier, A. P. Guerin, S. J. Marchais, M. E. Safar, and G. M. London Carotid Arterial Stiffness as a Predictor of Cardiovascular and All-Cause Mortality in End-Stage Renal Disease Hypertension, September 1, 1998; 32(3): 570 - 574. [Abstract] [Full Text] [PDF] |
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J. Blacher, K. Demuth, A. P. Guerin, M. E. Safar, N. Moatti, and G. M. London Influence of Biochemical Alterations on Arterial Stiffness in Patients With End-stage Renal Disease Arterioscler Thromb Vasc Biol, April 1, 1998; 18(4): 535 - 541. [Abstract] [Full Text] [PDF] |
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G. F. Mitchell, L. A. Moye, E. Braunwald, J.-L. Rouleau, V. Bernstein, E. M. Geltman, G. C. Flaker, M. A. Pfeffer, and f. t. S. Investigators Sphygmomanometrically Determined Pulse Pressure Is a Powerful Independent Predictor of Recurrent Events After Myocardial Infarction in Patients With Impaired Left Ventricular Function Circulation, December 16, 1997; 96(12): 4254 - 4260. [Abstract] [Full Text] |
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G. F. Mitchell, M. A. Pfeffer, P. V. Finn, and J. M. Pfeffer Comparison of techniques for measuring pulse-wave velocity in the rat J Appl Physiol, January 1, 1997; 82(1): 203 - 210. [Abstract] [Full Text] [PDF] |
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K.-S. Hsieh, P.-L. Chen, and S.-E. Fu A Simple, Noninvasive Method to Investigate Vascular Characteristics in Children Angiology, April 1, 1996; 47(4): 361 - 367. [Abstract] [PDF] |
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C. Bonithon-Kopp, P. J. Touboul, C. Berr, C. Magne, and P. Ducimetiere Factors of Carotid Arterial Enlargement in a Population Aged 59 to 71 Years : The EVA Study Stroke, April 1, 1996; 27(4): 654 - 660. [Abstract] [Full Text] |
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Y. Matsumoto, T. Honda, M. Hamada, H. Matsuoka, and K. Hiwada Evaluation of Aortic Distensibility in Patients with Coronary Artery Disease by Use of Cine Magnetic Resonance Angiology, February 1, 1996; 47(2): 149 - 155. [Abstract] [PDF] |
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M.W. Ramsey, J. Goodfellow, C.J.H. Jones, L.A. Luddington, M.J. Lewis, and A.H. Henderson Endothelial Control of Arterial Distensibility Is Impaired in Chronic Heart Failure Circulation, December 1, 1995; 92(11): 3212 - 3219. [Abstract] [Full Text] |
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C. Stefanadis, C. Stratos, C. Vlachopoulos, S. Marakas, H. Boudoulas, I. Kallikazaros, E. Tsiamis, K. Toutouzas, L. Sioros, and P. Toutouzas Pressure-Diameter Relation of the Human Aorta : A New Method of Determination by the Application of a Special Ultrasonic Dimension Catheter Circulation, October 15, 1995; 92(8): 2210 - 2219. [Abstract] [Full Text] |
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G. M. London, A. P. Guerin, B. Pannier, S. J. Marchais, and M. Stimpel Influence of Sex on Arterial Hemodynamics and Blood Pressure : Role of Body Height Hypertension, September 1, 1995; 26(3): 514 - 519. [Abstract] [Full Text] |
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M. O'Rourke Mechanical Principles in Arterial Disease Hypertension, July 1, 1995; 26(1): 2 - 9. [Full Text] |
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A. Avolio Genetic and Environmental Factors in the Function and Structure of the Arterial Wall Hypertension, July 1, 1995; 26(1): 34 - 37. [Abstract] [Full Text] |
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R. Reghunandanan, S. Sood, V. Reghunandanan, R. Nagpaul, P.S. Suresh, and P. I. B. Singh Pulse Wave Velocity and Lipid Profile in Varicose Vein Patients Angiology, May 1, 1995; 46(5): 409 - 412. [Abstract] [PDF] |
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H. Shimamoto and Y. Shimamoto Lisinopril Improves Aortic Compliance and Renal Flow : Comparison With Nifedipine Hypertension, March 1, 1995; 25(3): 327 - 334. [Abstract] [Full Text] |
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G. I. Barbash, H. D. White, M. Modan, R. Diaz, J. R. Hampton, J. Heikkila, A. Kristinsson, S. Moulopoulos, E. A. C. Paolasso, T. Van der Werf, et al. Outcome of Thrombolytic Therapy in Relation to Hospital Size and Invasive Cardiac Services Arch Intern Med, October 10, 1994; 154(19): 2237 - 2242. [Abstract] [PDF] |
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T. Sumimoto, M. Hamada, H. Kawakami, M. Suzuki, M. Abe, H. Matsuoka, Y. Shigematsu, and K. Hiwada Effects of Glyceryl Trinitrate on Blood Pressure and Arterial Compliance Angiology, December 1, 1993; 44(12): 951 - 957. [Abstract] [PDF] |
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R. J. Cody, S. Torre, M. Clark, and K. Pondolfino Age-Related Hemodynamic, Renal, and Hormonal Differences Among Patients With Congestive Heart Failure Arch Intern Med, May 1, 1989; 149(5): 1023 - 1028. [Abstract] [PDF] |
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B.M. Pannier, M.E. Safar, S. Laurent, and G.M. London Indirect, Noninvasive Evaluation of Pressure Wave Transmission in Essential Hypertension Angiology, January 1, 1989; 40(1): 29 - 35. [Abstract] [PDF] |
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