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Circulation. 1983;68:50-58

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Circulation, Vol 68, 50-58, Copyright © 1983 by American Heart Association


ARTICLES

Effects of aging on changing arterial compliance and left ventricular load in a northern Chinese urban community

AP Avolio, SG Chen, RP Wang, CL Zhang, MF Li and MF O'Rourke

Pulse wave velocity (PWV) was measured by means of transcutaneous Doppler techniques in the aorta, right arm, and right leg of 480 normal subjects of both sexes in urban Beijing, China (age range 3 to 89 years, mean age 41 +/- 20.8 SD); supine blood pressure was recorded in the brachial artery of each subject with standard sphygmomanometric procedures. Serum cholesterol was determined in a subgroup of 79 subjects (age 17 to 85 years, mean 47 +/- 26 SD). PWV (y in cm/sec) was found to vary with age (x, years) at each of the three locations according to the following regression equations: aorta, y = 9.2x + 615, r = .673 (p less than .001); right arm, y = 4.8x + 998, r = .453 (p less than .001); right leg, y = 5.6x + 791, r = .630 (p less than .001). Systolic, diastolic, mean, and pulse pressures were found to increase with age. PWV also increased with mean supine blood pressure but was not related to serum cholesterol (average 4.49 +/- 0.11 [SEM], mmol/l). Compared with that of Western populations, serum cholesterol tended to be lower at all age groups, systolic pressure higher at ages over 35 years, and PWV higher at all ages. Because change in PWV is directly related to change in arterial compliance, these results indicate that aging and not concomitant atherosclerosis (known to be rare in Asian populations) is the dominant factor associated with reduced arterial compliance and increased left ventricular load in these subjects.


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Hypertension, October 1, 2000; 36(4): 489 - 494.
[Abstract] [Full Text] [PDF]


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Nephrol Dial TransplantHome page
A. P. Guerin, G. M. London, S. J. Marchais, and F. Metivier
Arterial stiffening and vascular calcifications in end-stage renal disease
Nephrol. Dial. Transplant., July 1, 2000; 15(7): 1014 - 1021.
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HypertensionHome page
J. J. van der Heijden-Spek, J. A. Staessen, R. H. Fagard, A. P. Hoeks, H. A. S. Boudier, and L. M. Van Bortel
Effect of Age on Brachial Artery Wall Properties Differs From the Aorta and Is Gender Dependent : A Population Study
Hypertension, February 1, 2000; 35(2): 637 - 642.
[Abstract] [Full Text] [PDF]


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J Am Coll CardiolHome page
P. J. Chowienczyk, R. P. Kelly, H. MacCallum, S. C. Millasseau, T. L. G. Andersson, R. G. Gosling, J. M. Ritter, and E. E. Anggard
Photoplethysmographic assessment of pulse wave reflection: Blunted response to endothelium-dependent beta2-adrenergic vasodilation in type II diabetes mellitus
J. Am. Coll. Cardiol., December 1, 1999; 34(7): 2007 - 2014.
[Abstract] [Full Text] [PDF]


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Am. J. Physiol. Heart Circ. Physiol.Home page
A. Nussbacher, G. Gerstenblith, F. C. O'connor, L. C. Becker, D. A. Kass, S. P. Schulman, J. L. Fleg, and E. G. Lakatta
Hemodynamic effects of unloading the old heart
Am J Physiol Heart Circ Physiol, November 1, 1999; 277(5): H1863 - H1871.
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QJMHome page
Yasmin and M.J. Brown
Similarities and differences between augmentation index and pulse wave velocity in the assessment of arterial stiffness
QJM, October 1, 1999; 92(10): 595 - 600.
[Abstract] [Full Text] [PDF]


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Am. J. Physiol. Heart Circ. Physiol.Home page
M. Karamanoglu and M. P. Feneley
Late systolic pressure augmentation: role of left ventricular outflow patterns
Am J Physiol Heart Circ Physiol, August 1, 1999; 277(2): H481 - H487.
[Abstract] [Full Text] [PDF]


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HypertensionHome page
D. A. Bertovic, T. K. Waddell, C. D. Gatzka, J. D. Cameron, A. M. Dart, and B. A. Kingwell
Muscular Strength Training Is Associated With Low Arterial Compliance and High Pulse Pressure
Hypertension, June 1, 1999; 33(6): 1385 - 1391.
[Abstract] [Full Text] [PDF]


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HypertensionHome page
G. E. McVeigh, C. W. Bratteli, D. J. Morgan, C. M. Alinder, S. P. Glasser, S. M. Finkelstein, and J. N. Cohn
Age-Related Abnormalities in Arterial Compliance Identified by Pressure Pulse Contour Analysis : Aging and Arterial Compliance
Hypertension, June 1, 1999; 33(6): 1392 - 1398.
[Abstract] [Full Text] [PDF]


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CirculationHome page
J. Blacher, A. P. Guerin, B. Pannier, S. J. Marchais, M. E. Safar, and G. M. London
Impact of Aortic Stiffness on Survival in End-Stage Renal Disease
Circulation, May 11, 1999; 99(18): 2434 - 2439.
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J Am Coll CardiolHome page
C.-H. Chen, M. Nakayama, M. Talbot, E. Nevo, B. Fetics, G. Gerstenblith, L. C. Becker, and D. A. Kass
Verapamil acutely reduces ventricular-vascular stiffening and improves aerobic exercise performance in elderly individuals
J. Am. Coll. Cardiol., May 1, 1999; 33(6): 1602 - 1609.
[Abstract] [Full Text] [PDF]


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HypertensionHome page
J. Blacher, R. Asmar, S. Djane, G. M. London, and M. E. Safar
Aortic Pulse Wave Velocity as a Marker of Cardiovascular Risk in Hypertensive Patients
Hypertension, May 1, 1999; 33(5): 1111 - 1117.
[Abstract] [Full Text] [PDF]


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J Am Coll CardiolHome page
C.-H. Chen, M. Nakayama, E. Nevo, B. J. Fetics, W. L. Maughan, and D. A. Kass
Coupled systolic-ventricular and vascular stiffening with age: Implications for pressure regulation and cardiac reserve in the elderly
J. Am. Coll. Cardiol., November 1, 1998; 32(5): 1221 - 1227.
[Abstract] [Full Text] [PDF]


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HypertensionHome page
J. Blacher, B. Pannier, A. P. Guerin, S. J. Marchais, M. E. Safar, and G. M. London
Carotid Arterial Stiffness as a Predictor of Cardiovascular and All-Cause Mortality in End-Stage Renal Disease
Hypertension, September 1, 1998; 32(3): 570 - 574.
[Abstract] [Full Text] [PDF]


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Arterioscler. Thromb. Vasc. Bio.Home page
J. Blacher, K. Demuth, A. P. Guerin, M. E. Safar, N. Moatti, and G. M. London
Influence of Biochemical Alterations on Arterial Stiffness in Patients With End-stage Renal Disease
Arterioscler Thromb Vasc Biol, April 1, 1998; 18(4): 535 - 541.
[Abstract] [Full Text] [PDF]


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CirculationHome page
G. F. Mitchell, L. A. Moye, E. Braunwald, J.-L. Rouleau, V. Bernstein, E. M. Geltman, G. C. Flaker, M. A. Pfeffer, and f. t. S. Investigators
Sphygmomanometrically Determined Pulse Pressure Is a Powerful Independent Predictor of Recurrent Events After Myocardial Infarction in Patients With Impaired Left Ventricular Function
Circulation, December 16, 1997; 96(12): 4254 - 4260.
[Abstract] [Full Text]


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J. Appl. Physiol.Home page
G. F. Mitchell, M. A. Pfeffer, P. V. Finn, and J. M. Pfeffer
Comparison of techniques for measuring pulse-wave velocity in the rat
J Appl Physiol, January 1, 1997; 82(1): 203 - 210.
[Abstract] [Full Text] [PDF]


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ANGIOLOGYHome page
K.-S. Hsieh, P.-L. Chen, and S.-E. Fu
A Simple, Noninvasive Method to Investigate Vascular Characteristics in Children
Angiology, April 1, 1996; 47(4): 361 - 367.
[Abstract] [PDF]


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StrokeHome page
C. Bonithon-Kopp, P. J. Touboul, C. Berr, C. Magne, and P. Ducimetiere
Factors of Carotid Arterial Enlargement in a Population Aged 59 to 71 Years : The EVA Study
Stroke, April 1, 1996; 27(4): 654 - 660.
[Abstract] [Full Text]


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ANGIOLOGYHome page
Y. Matsumoto, T. Honda, M. Hamada, H. Matsuoka, and K. Hiwada
Evaluation of Aortic Distensibility in Patients with Coronary Artery Disease by Use of Cine Magnetic Resonance
Angiology, February 1, 1996; 47(2): 149 - 155.
[Abstract] [PDF]


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CirculationHome page
M.W. Ramsey, J. Goodfellow, C.J.H. Jones, L.A. Luddington, M.J. Lewis, and A.H. Henderson
Endothelial Control of Arterial Distensibility Is Impaired in Chronic Heart Failure
Circulation, December 1, 1995; 92(11): 3212 - 3219.
[Abstract] [Full Text]


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CirculationHome page
C. Stefanadis, C. Stratos, C. Vlachopoulos, S. Marakas, H. Boudoulas, I. Kallikazaros, E. Tsiamis, K. Toutouzas, L. Sioros, and P. Toutouzas
Pressure-Diameter Relation of the Human Aorta : A New Method of Determination by the Application of a Special Ultrasonic Dimension Catheter
Circulation, October 15, 1995; 92(8): 2210 - 2219.
[Abstract] [Full Text]


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HypertensionHome page
G. M. London, A. P. Guerin, B. Pannier, S. J. Marchais, and M. Stimpel
Influence of Sex on Arterial Hemodynamics and Blood Pressure : Role of Body Height
Hypertension, September 1, 1995; 26(3): 514 - 519.
[Abstract] [Full Text]


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HypertensionHome page
M. O'Rourke
Mechanical Principles in Arterial Disease
Hypertension, July 1, 1995; 26(1): 2 - 9.
[Full Text]


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HypertensionHome page
A. Avolio
Genetic and Environmental Factors in the Function and Structure of the Arterial Wall
Hypertension, July 1, 1995; 26(1): 34 - 37.
[Abstract] [Full Text]


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ANGIOLOGYHome page
R. Reghunandanan, S. Sood, V. Reghunandanan, R. Nagpaul, P.S. Suresh, and P. I. B. Singh
Pulse Wave Velocity and Lipid Profile in Varicose Vein Patients
Angiology, May 1, 1995; 46(5): 409 - 412.
[Abstract] [PDF]


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HypertensionHome page
H. Shimamoto and Y. Shimamoto
Lisinopril Improves Aortic Compliance and Renal Flow : Comparison With Nifedipine
Hypertension, March 1, 1995; 25(3): 327 - 334.
[Abstract] [Full Text]


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Arch Intern MedHome page
G. I. Barbash, H. D. White, M. Modan, R. Diaz, J. R. Hampton, J. Heikkila, A. Kristinsson, S. Moulopoulos, E. A. C. Paolasso, T. Van der Werf, et al.
Outcome of Thrombolytic Therapy in Relation to Hospital Size and Invasive Cardiac Services
Arch Intern Med, October 10, 1994; 154(19): 2237 - 2242.
[Abstract] [PDF]


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ANGIOLOGYHome page
T. Sumimoto, M. Hamada, H. Kawakami, M. Suzuki, M. Abe, H. Matsuoka, Y. Shigematsu, and K. Hiwada
Effects of Glyceryl Trinitrate on Blood Pressure and Arterial Compliance
Angiology, December 1, 1993; 44(12): 951 - 957.
[Abstract] [PDF]


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Arch Intern MedHome page
R. J. Cody, S. Torre, M. Clark, and K. Pondolfino
Age-Related Hemodynamic, Renal, and Hormonal Differences Among Patients With Congestive Heart Failure
Arch Intern Med, May 1, 1989; 149(5): 1023 - 1028.
[Abstract] [PDF]


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ANGIOLOGYHome page
B.M. Pannier, M.E. Safar, S. Laurent, and G.M. London
Indirect, Noninvasive Evaluation of Pressure Wave Transmission in Essential Hypertension
Angiology, January 1, 1989; 40(1): 29 - 35.
[Abstract] [PDF]