Circulation, Vol 67, 1129-1138, Copyright © 1983 by American Heart Association
P Denes, P Santarelli, RG Hauser and EF Uretz
Quantitative analysis of the high-frequency components of the terminal
portion of the surface QRS was performed in 42 normal subjects (group 1,
ages 18-67 years, mean +/- SEM 34.7 +/- 2.2 years) and in 12 patients with
symptomatic, sustained ventricular tachycardia (VT) (group 2, ages 48-76
years, mean 59 +/- 2.3 years). Signal averaging and high-pass,
bidirectional digital filtering were used for analysis. The total duration
of the QRS, the duration of the low-amplitude signals (less than 40 microV)
in the terminal portion of the QRS and the amplitude of the signals in the
last 40 and 50 msec of the QRS were measured at filter settings of 25 and
40 Hz. Reproducibility of the measurements was tested in 15 normal subjects
by comparing results obtained from two consecutive recordings. Significant
differences were found between normal subjects and VT patients for all four
indexes at both 25- and 40-Hz filters. Specific values for each of the
indexes were identified at the 40-Hz filtering, which could separate normal
subjects from VT patients (20 microV for the amplitude of last 40 msec; 30
microV for the amplitude of last 50 msec; 120 msec for the total duration;
and 39 msec for the low-amplitude signal of the filtered QRS). Using these
values for the four indexes, respectively, 90%, 98%, 100% and 90% of the
normal subjects and 83%, 83%, 58% and 83% for the VT group were correctly
classified. The results show that the high- frequency analysis of the
signal-averaged body surface QRS is a reliable, reproducible, noninvasive
method for distinguishing patients with VT from normal subjects.
ARTICLES
Quantitative analysis of the high-frequency components of the terminal portion of the body surface QRS in normal subjects and in patients with ventricular tachycardia
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