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Circulation. 1982;65:457-464

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*Heart Diseases

Circulation, Vol 65, 457-464, Copyright © 1982 by American Heart Association


ARTICLES

Clinical classification of cardiac deaths

LE Hinkle Jr and HT Thaler

One hundred forty-two deaths among 743 men ages 50 - 65 years who had been examined and followed 5 - 10 years were investigated and classified on the basis of clinical information from medical and non- medical observers, ECGs and autopsies. A classification based on the condition of the circulation immediately before death appears to be most relevant to studies of sudden death. In 58% of the cases, the subjects collapsed abruptly and his pulse ceased without prior circulatory collapse (arrhythmic death); in 42%, the pulse ceased only after the peripheral circulation had collapsed (deaths in circulatory failure). Thirty-three percent of arrhythmic deaths and 10% of deaths in circulatory failure occurred in a setting of clinical evidence of acute ischemic heart disease (p less than 0.005). Forty-five percent of arrhythmic deaths were preceded by chronic congestive heart failure without circulatory collapse. Ninety-three percent of final illnesses that lasted less than 1 hour ended in arrhythmic deaths; 74% lasted more than 1 day ended in deaths in circulatory failure (p less than 0.001). Eighty-eight percent of deaths that occurred outside of the hospital were arrhythmic; 71% of deaths that occurred in the hospital were deaths in circulatory failure (p less than 0.001). Ninety percent of deaths in which the primary cause of the final illness was heart disease were arrhythmic; 86% of deaths in which the primary cause was other than heart disease were deaths in circulatory failure (p less than 0.001). Ninety-one percent of deaths precipitated by an acute cardiac event were arrhythmic; 98% precipitated by acute respiratory obstruction, hemorrhage, infection, stroke or other noncardiac events were deaths in circulatory failure (p less than 0.001).


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Identification of Patients Most Likely to Benefit From Implantable Cardioverter-Defibrillator Therapy : The Canadian Implantable Defibrillator Study
Circulation, April 11, 2000; 101(14): 1660 - 1664.
[Abstract] [Full Text] [PDF]


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NEJMHome page
D. Roy, M. Talajic, P. Dorian, S. Connolly, M. J. Eisenberg, M. Green, T. Kus, J. Lambert, M. Dubuc, P. Gagne, et al.
Amiodarone to Prevent Recurrence of Atrial Fibrillation
N. Engl. J. Med., March 30, 2000; 342(13): 913 - 920.
[Abstract] [Full Text] [PDF]


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CirculationHome page
S. J. Connolly, M. Gent, R. S. Roberts, P. Dorian, D. Roy, R. S. Sheldon, L. B. Mitchell, M. S. Green, G. J. Klein, and B. O’Brien
Canadian Implantable Defibrillator Study (CIDS) : A Randomized Trial of the Implantable Cardioverter Defibrillator Against Amiodarone
Circulation, March 21, 2000; 101(11): 1297 - 1302.
[Abstract] [Full Text] [PDF]


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Eur Heart JHome page
L. Fauchier, D. Babuty, P. Poret, D. Casset-Senon, M.L. Autret, P. Cosnay, and J.P. Fauchier
Comparison of long-term outcome of alcoholic and idiopathic dilated cardiomyopathy
Eur. Heart J., February 2, 2000; 21(4): 306 - 314.
[Abstract] [PDF]


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CirculationHome page
J. R. Teerlink, M. Jalaluddin, S. Anderson, M. L. Kukin, E. J. Eichhorn, G. Francis, M. Packer, and B. M. Massie
Ambulatory Ventricular Arrhythmias in Patients With Heart Failure Do Not Specifically Predict an Increased Risk of Sudden Death
Circulation, January 4, 2000; 101(1): 40 - 46.
[Abstract] [Full Text] [PDF]


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NEJMHome page
A. E. Buxton, K. L. Lee, J. D. Fisher, M. E. Josephson, E. N. Prystowsky, G. Hafley, and The Multicenter Unsustained Tachycardia Trial Inve
A Randomized Study of the Prevention of Sudden Death in Patients with Coronary Artery Disease
N. Engl. J. Med., December 16, 1999; 341(25): 1882 - 1890.
[Abstract] [Full Text] [PDF]


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J Am Coll CardiolHome page
F. Grigioni, M. Enriquez-Sarano, L. H. Ling, K. R. Bailey, J. B. Seward, A. J. Tajik, and R. L. Frye
Sudden death in mitral regurgitation due to flail leaflet
J. Am. Coll. Cardiol., December 1, 1999; 34(7): 2078 - 2085.
[Abstract] [Full Text] [PDF]


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Eur Heart JHome page
C.M Pratt, A.J Camm, J.T Bigger Jr, G Breithardt, R.W.F Campbell, A.E Epstein, L.J Kappenberger, K.-H Kuck, S Pocock, S Saksena, et al.
Evaluation of antiarrhythmic drug efficacy in patients with an ICD. Unlimited potential or replete with complexity and problems?
Eur. Heart J., November 1, 1999; 20(21): 1538 - 1552.
[Abstract] [PDF]


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CirculationHome page
L. H. Ling, J. K. Oh, H. V. Schaff, G. K. Danielson, D. W. Mahoney, J. B. Seward, and A. J. Tajik
Constrictive Pericarditis in the Modern Era : Evolving Clinical Spectrum and Impact on Outcome After Pericardiectomy
Circulation, September 28, 1999; 100(13): 1380 - 1386.
[Abstract] [Full Text] [PDF]


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CirculationHome page
C. M. Albert, J. E. Manson, N. R. Cook, U. A. Ajani, J. M. Gaziano, and C. H. Hennekens
Moderate Alcohol Consumption and the Risk of Sudden Cardiac Death Among US Male Physicians
Circulation, August 31, 1999; 100(9): 944 - 950.
[Abstract] [Full Text] [PDF]


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CirculationHome page
A. J. Moss, R. E. Goldstein, V. J. Marder, C. E. Sparks, D. Oakes, H. Greenberg, H. J. Weiss, W. Zareba, M. W. Brown, C.-S. Liang, et al.
Thrombogenic Factors and Recurrent Coronary Events
Circulation, May 18, 1999; 99(19): 2517 - 2522.
[Abstract] [Full Text] [PDF]


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J Am Coll CardiolHome page
L. Fauchier, D. Babuty, P. Cosnay, and J. P. Fauchier
Prognostic value of heart rate variability for sudden death and major arrhythmic events in patients with idiopathic dilated cardiomyopathy
J. Am. Coll. Cardiol., April 1, 1999; 33(5): 1203 - 1207.
[Abstract] [Full Text] [PDF]


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CirculationHome page
J. T. Bigger Jr, W. Whang, J. N. Rottman, R. E. Kleiger, C. D. Gottlieb, P. B. Namerow, R. C. Steinman, and N. A. M. Estes III
Mechanisms of Death in the CABG Patch Trial : A Randomized Trial of Implantable Cardiac Defibrillator Prophylaxis in Patients at High Risk of Death After Coronary Artery Bypass Graft Surgery
Circulation, March 23, 1999; 99(11): 1416 - 1421.
[Abstract] [Full Text] [PDF]


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J Am Coll CardiolHome page
D. Andresen, G. Steinbeck, T. Bruggemann, D. Muller, R. Haberl, S. Behrens, E. Hoffmann, K. Wegscheider, R.u. Dissmann, and H.-C. Ehlers
Risk stratification following myocardial infarction in the thrombolytic era: a two-step strategy using noninvasive and invasive methods
J. Am. Coll. Cardiol., January 1, 1999; 33(1): 131 - 138.
[Abstract] [Full Text] [PDF]


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J Am Coll CardiolHome page
W. Grimm, J.u. Hoffmann, V. Menz, K. Luck, and B. Maisch
Programmed ventricular stimulation for arrhythmia risk prediction in patients with idiopathic dilated cardiomyopathy and nonsustained ventricular tachycardia
J. Am. Coll. Cardiol., September 1, 1998; 32(3): 739 - 745.
[Abstract] [Full Text] [PDF]


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PediatricsHome page
A. Arola, J. Tuominen, O. Ruuskanen, and E. Jokinen
Idiopathic Dilated Cardiomyopathy in Children: Prognostic Indicators and Outcome
Pediatrics, March 1, 1998; 101(3): 369 - 376.
[Abstract] [Full Text] [PDF]


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JAMAHome page
C. M. Albert, C. H. Hennekens, C. J. O'Donnell, U. A. Ajani, V. J. Carey, W. C. Willett, J. N. Ruskin, and J. E. Manson
Fish Consumption and Risk of Sudden Cardiac Death
JAMA, January 7, 1998; 279(1): 23 - 28.
[Abstract] [Full Text] [PDF]


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CirculationHome page
A. C. Caruso, F. I. Marcus, E. A. Hahn, V. L. Hartz, and J. W. Mason
Predictors of Arrhythmic Death and Cardiac Arrest in the ESVEM Trial
Circulation, September 16, 1997; 96(6): 1888 - 1892.
[Abstract] [Full Text]


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NEJMHome page
C. M. Albert, J. E. Manson, C. H. Hennekens, J. N. Ruskin, A. H. Lichtenstein, R. Bhopal, M. L. Daviglus, J. Stamler, and P. Greenland
Fish Consumption and the Risk of Myocardial Infarction
N. Engl. J. Med., August 14, 1997; 337(7): 497 - 499.
[Full Text]


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NEJMHome page
A. J. Moss, W. J. Hall, D. S. Cannom, J. P. Daubert, S. L. Higgins, H. Klein, J. H. Levine, S. Saksena, A. L. Waldo, D. Wilber, et al.
Improved Survival with an Implanted Defibrillator in Patients with Coronary Disease at High Risk for Ventricular Arrhythmia
N. Engl. J. Med., December 26, 1996; 335(26): 1933 - 1940.
[Abstract] [Full Text] [PDF]


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CirculationHome page
J. T. Bigger Jr, R. C. Steinman, L. M. Rolnitzky, J. L. Fleiss, P. Albrecht, and R. J. Cohen
Power Law Behavior of RR-Interval Variability in Healthy Middle-Aged Persons, Patients With Recent Acute Myocardial Infarction, and Patients With Heart Transplants
Circulation, June 15, 1996; 93(12): 2142 - 2151.
[Abstract] [Full Text]


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CirculationHome page
C. M. Pratt, P. S. Greenway, M. H. Schoenfeld, M. L. Hibben, and J. A. Reiffel
Exploration of the Precision of Classifying Sudden Cardiac Death : Implications for the Interpretation of Clinical Trials
Circulation, February 1, 1996; 93(3): 519 - 524.
[Abstract] [Full Text]


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CirculationHome page
A. R. R. Misier, T. Opthof, N. M. van Hemel, J. T. Vermeulen, J. M.T. de Bakker, J. J.A.M. Defauw, F. J.L. van Capelle, and M. J. Janse
Dispersion of `Refractoriness' in Noninfarcted Myocardium of Patients With Ventricular Tachycardia or Ventricular Fibrillation After Myocardial Infarction
Circulation, May 15, 1995; 91(10): 2566 - 2572.
[Abstract] [Full Text]


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CirculationHome page
J. D. Curb, B. L. Rodriguez, C. M. Burchfiel, R. D. Abbott, D. Chiu, and K. Yano
Sudden Death, Impaired Glucose Tolerance, and Diabetes in Japanese American Men
Circulation, May 15, 1995; 91(10): 2591 - 2595.
[Abstract] [Full Text]


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NEJMHome page
J. W. Mason and The Electrophysiologic Study versus Electrocardiog
A Comparison of Electrophysiologic Testing with Holter Monitoring to Predict Antiarrhythmic-Drug Efficacy for Ventricular Tachyarrhythmias
N. Engl. J. Med., August 12, 1993; 329(7): 445 - 451.
[Abstract] [Full Text]


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JAMAHome page
A. J. Moss, R. E. Goldstein, W. J. Hall, J. T. Bigger Jr, J. L. Fleiss, H. Greenberg, M. Bodenheimer, R. J. Krone, F. I. Marcus, F. J. Th. Wackers, et al.
Detection and Significance of Myocardial Ischemia in Stable Patients After Recovery From an Acute Coronary Event
JAMA, May 12, 1993; 269(18): 2379 - 2385.
[Abstract] [PDF]


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NEJMHome page
B. H. Lorell, P. Dorian, D. Newman, R. Muller, H. M. Steffen, W. Krone, C. D. Furberg, R. W.F. Campbell, B. Pitt, M. A. Pfeffer, et al.
ACE Inhibitors after Myocardial Infarction
N. Engl. J. Med., April 1, 1993; 328(13): 966 - 969.
[Full Text]


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JAMAHome page
R. C. Baron, S. B. Thacker, L. Gorelkin, A. A. Vernon, W. R. Taylor, and K. Choi
Sudden Death Among Southeast Asian Refugees: An Unexplained Nocturnal Phenomenon
JAMA, December 2, 1983; 250(21): 2947 - 2951.
[Abstract] [PDF]


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ANN INTERN MEDHome page
M. MIROWSKI, P. R. REID, R. A. WINKLE, M. M. MOWER, L. WATKINS Jr., E. B. STINSON, L. S. C. GRIFFITH, C. H. KALLMAN, and M. L. WEISFELDT
Mortality in Patients with Implanted Automatic Defibrillators
Ann Intern Med, May 1, 1983; 98(5_Part_1): 585 - 588.
[Abstract] [PDF]


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ANN INTERN MEDHome page
Cardiovascular Diseases: An Annotated Bibliography of Recent Literature: References to Journal Articles and Other Papers
Ann Intern Med, May 1, 1983; 98(5_Part_1): 679 - 685.
[Abstract] [PDF]